Detailed information NTG0975912

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: ACM3HZ_RS04545
• Genome accession: NZ_CP180684
• Coordinates: 804387..805172 (+)
• Length: 261 a.a.
• NCBI ID: WP_000825431.1
• Uniprot ID: Q8E0P2
• Organism: Streptococcus agalactiae strain M18
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 799387..810172

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM3HZ_RS04515 (ACM3HZ_04515)	-	800504..800947 (+)	444	WP_001048166.1	hypothetical protein	-
ACM3HZ_RS04520 (ACM3HZ_04520)	-	801032..801298 (+)	267	WP_001865676.1	hypothetical protein	-
ACM3HZ_RS04525 (ACM3HZ_04525)	-	801399..801527 (+)	129	WP_000962057.1	hypothetical protein	-
ACM3HZ_RS04530 (ACM3HZ_04530)	-	801536..801856 (+)	321	WP_001865677.1	hypothetical protein	-
ACM3HZ_RS04535 (ACM3HZ_04535)	-	801953..802624 (+)	672	WP_000891268.1	ATP-binding cassette domain-containing protein	-
ACM3HZ_RS04540 (ACM3HZ_04540)	-	802681..804126 (-)	1446	WP_000750933.1	FAD/NAD(P)-binding protein	-
ACM3HZ_RS04545 (ACM3HZ_04545)	endA	804387..805172 (+)	786	WP_000825431.1	DNA/RNA non-specific endonuclease	Machinery gene
ACM3HZ_RS04550 (ACM3HZ_04550)	-	805250..805888 (-)	639	WP_000478529.1	VTT domain-containing protein	-
ACM3HZ_RS04555 (ACM3HZ_04555)	-	806105..806761 (+)	657	WP_000121094.1	ATP-binding cassette domain-containing protein	-
ACM3HZ_RS04560 (ACM3HZ_04560)	-	806758..807531 (+)	774	WP_000012390.1	ABC transporter permease	-
ACM3HZ_RS04565 (ACM3HZ_04565)	-	807695..808513 (+)	819	WP_000601007.1	hypothetical protein	-
ACM3HZ_RS04570 (ACM3HZ_04570)	-	808550..809434 (-)	885	WP_416055475.1	LysR family transcriptional regulator	-
ACM3HZ_RS04575 (ACM3HZ_04575)	-	809627..810133 (+)	507	Protein_821	PTS sugar transporter subunit IIC	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 29424.86 Da
• Isoelectric Point: 8.9989

>NTDB_id=975912 ACM3HZ_RS04545 WP_000825431.1 804387..805172(+) (endA) [Streptococcus agalactiae strain M18]
MKRLHKLFITVIATLGMLGVMTFGLPTQPQNVTPIVHADVNSSVDTSQEFQNNLKNAIGNLPFQYVNGIYELNNNQTNLN
ADVNVKAYVQNTIDNQQRLSTANAMLDRTIRQYQNRRDTTLPDANWKPLGWHQVATNDHYGHAVDKGHLIAYALAGNFKG
WDASVSNPQNVVTQTAHSNQSNQKINRGQNYYESLVRKAVDQNKRVRYRVTPLYRNDTDLVPFAMHLEAKSQDGTLEFNV
AIPNTQASYTMDYATGEITLN

Nucleotide

• Length: 786 bp

>NTDB_id=975912 ACM3HZ_RS04545 WP_000825431.1 804387..805172(+) (endA) [Streptococcus agalactiae strain M18]
ATGAAAAGATTACATAAACTGTTTATAACCGTAATTGCTACATTAGGTATGTTGGGGGTAATGACCTTTGGTCTTCCAAC
GCAGCCGCAAAACGTAACGCCGATAGTACATGCTGATGTCAATTCATCTGTTGATACGAGCCAGGAATTTCAAAATAATT
TAAAAAATGCTATTGGTAACCTACCATTTCAATATGTTAATGGTATTTATGAATTAAATAATAATCAGACAAATTTAAAT
GCTGATGTCAATGTTAAAGCGTATGTTCAAAATACAATTGACAATCAACAAAGACTATCAACTGCTAATGCAATGCTTGA
TAGAACCATTCGTCAATATCAAAATCGCAGAGATACCACTCTTCCCGATGCAAATTGGAAACCATTAGGTTGGCATCAAG
TAGCTACTAATGACCATTATGGACATGCAGTCGACAAGGGGCATTTAATTGCCTATGCTTTAGCTGGAAATTTCAAAGGT
TGGGATGCTTCCGTGTCAAATCCTCAAAATGTTGTCACACAAACAGCTCATTCCAACCAATCAAATCAAAAAATCAATCG
TGGACAAAATTATTATGAAAGCTTAGTTCGTAAGGCGGTTGACCAAAACAAACGTGTTCGTTACCGTGTAACTCCATTGT
ACCGTAATGATACTGATTTAGTTCCATTTGCAATGCACCTAGAAGCTAAATCACAAGATGGCACATTAGAATTTAATGTT
GCTATTCCAAACACACAAGCATCATACACTATGGATTATGCAACAGGAGAAATAACACTAAATTAA

Domains

Predicted by InterProScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (77-235)

3D structure

• AlphaFold DB: Q8E0P2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	51.515	75.862	0.391
endA	Streptococcus pneumoniae D39	51.515	75.862	0.391
endA	Streptococcus pneumoniae R6	51.515	75.862	0.391
endA	Streptococcus pneumoniae TIGR4	51.515	75.862	0.391