Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   R8775_RS09220 Genome accession   NZ_AP026915
Coordinates   1771840..1772664 (-) Length   274 a.a.
NCBI ID   WP_001036783.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700005     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1766840..1777664
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8775_RS09215 (PC0005_18010) - 1770218..1771549 (-) 1332 WP_000390043.1 hemolysin family protein -
  R8775_RS09220 (PC0005_18020) endA 1771840..1772664 (-) 825 WP_001036783.1 DNA-entry nuclease EndA Machinery gene
  R8775_RS09225 (PC0005_18030) - 1772703..1772891 (-) 189 WP_001813390.1 DNA-directed RNA polymerase subunit beta -
  R8775_RS09230 (PC0005_18040) murA 1772884..1774167 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  R8775_RS09235 (PC0005_18050) - 1774191..1774421 (-) 231 WP_000250393.1 DUF1146 family protein -
  R8775_RS09240 (PC0005_18060) sepM 1774479..1775516 (-) 1038 WP_000727268.1 SepM family pheromone-processing serine protease Regulator
  R8775_RS09245 (PC0005_18070) coaD 1775500..1775988 (-) 489 WP_001280723.1 pantetheine-phosphate adenylyltransferase -
  R8775_RS09250 (PC0005_18080) rsmD 1775978..1776517 (-) 540 WP_000706960.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  R8775_RS09255 (PC0005_18090) asnA 1776582..1777574 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29935.66 Da        Isoelectric Point: 10.1700

>NTDB_id=97589 R8775_RS09220 WP_001036783.1 1771840..1772664(-) (endA) [Streptococcus pneumoniae strain PZ900700005]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTKLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=97589 R8775_RS09220 WP_001036783.1 1771840..1772664(-) (endA) [Streptococcus pneumoniae strain PZ900700005]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCCAAAACCAAGCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

99.27

100

0.993
  endA Streptococcus pneumoniae D39

99.27

100

0.993
  endA Streptococcus pneumoniae R6

99.27

100

0.993
  endA Streptococcus pneumoniae TIGR4

99.27

100

0.993

Multiple sequence alignment