Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACL60T_RS11700 Genome accession   NZ_CP178659
Coordinates   2165153..2165809 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain VTB96933v     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2160153..2170809
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACL60T_RS11665 (ACL60T_11660) dcyD 2161032..2162018 (+) 987 WP_001128213.1 D-cysteine desulfhydrase -
  ACL60T_RS11670 (ACL60T_11665) tcyL 2162033..2162701 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ACL60T_RS11675 (ACL60T_11670) tcyN 2162698..2163450 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACL60T_RS11680 (ACL60T_11675) sdiA 2163680..2164402 (+) 723 WP_001154287.1 transcriptional regulator SdiA -
  ACL60T_RS11685 (ACL60T_11680) yecF 2164470..2164694 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACL60T_RS11690 (ACL60T_11685) yecU 2164681..2164857 (-) 177 WP_000590347.1 protein YecU -
  ACL60T_RS11695 (ACL60T_11690) - 2164895..2165011 (-) 117 WP_001302039.1 hypothetical protein -
  ACL60T_RS11700 (ACL60T_11695) letA 2165153..2165809 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACL60T_RS11705 (ACL60T_11700) uvrC 2165806..2167638 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACL60T_RS11710 (ACL60T_11705) pgsA 2167695..2168243 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACL60T_RS11730 (ACL60T_11725) yecA 2168893..2169558 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=972732 ACL60T_RS11700 WP_000611335.1 2165153..2165809(+) (letA) [Escherichia coli strain VTB96933v]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=972732 ACL60T_RS11700 WP_000611335.1 2165153..2165809(+) (letA) [Escherichia coli strain VTB96933v]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
TAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCTAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment