Detailed information NTG0971465

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: WOC44_RS02560
• Genome accession: NZ_CP150737
• Coordinates: 463196..464239 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM22723
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 458196..469239

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC44_RS02530 (WOC44_02530)	-	458624..458734 (+)	111	WP_001790257.1	hypothetical protein	-
WOC44_RS02535 (WOC44_02535)	-	458763..459176 (+)	414	WP_001549145.1	hypothetical protein	-
WOC44_RS02540 (WOC44_02540)	-	459607..460593 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
WOC44_RS02545 (WOC44_02545)	map	461121..461879 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
WOC44_RS02550 (WOC44_02550)	-	462096..462483 (+)	388	Protein_495	hypothetical protein	-
WOC44_RS02555 (WOC44_02555)	liaF	462498..463199 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
WOC44_RS02560 (WOC44_02560)	vraS	463196..464239 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
WOC44_RS02565 (WOC44_02565)	vraR	464229..464858 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
WOC44_RS02570 (WOC44_02570)	-	464974..466191 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
WOC44_RS02575 (WOC44_02575)	-	466469..466744 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
WOC44_RS02580 (WOC44_02580)	-	466751..467215 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
WOC44_RS02585 (WOC44_02585)	-	467362..467562 (+)	201	WP_000180461.1	DUF1128 family protein	-
WOC44_RS02590 (WOC44_02590)	-	467565..468821 (+)	1257	WP_001795438.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=971465 WOC44_RS02560 WP_001017131.1 463196..464239(+) (vraS) [Staphylococcus aureus strain TUM22723]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=971465 WOC44_RS02560 WP_001017131.1 463196..464239(+) (vraS) [Staphylococcus aureus strain TUM22723]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1