Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   ACJWMD_RS10960 Genome accession   NZ_CP177182
Coordinates   2300862..2302805 (-) Length   647 a.a.
NCBI ID   WP_002887309.1    Uniprot ID   -
Organism   Streptococcus salivarius strain MRD6060     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 2295862..2307805
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMD_RS10940 - 2296296..2296888 (-) 593 Protein_2100 hypothetical protein -
  ACJWMD_RS10945 - 2296969..2299212 (-) 2244 WP_002887306.1 hypothetical protein -
  ACJWMD_RS10950 - 2299216..2300421 (-) 1206 WP_002887307.1 hypothetical protein -
  ACJWMD_RS10955 - 2300442..2300789 (-) 348 WP_002887308.1 hypothetical protein -
  ACJWMD_RS10960 clpE 2300862..2302805 (-) 1944 WP_002887309.1 AAA family ATPase Regulator
  ACJWMD_RS10965 - 2302806..2303207 (-) 402 WP_002887310.1 hypothetical protein -
  ACJWMD_RS10970 - 2303218..2303616 (-) 399 WP_002887311.1 hypothetical protein -
  ACJWMD_RS10975 - 2303652..2304749 (-) 1098 WP_139053039.1 hypothetical protein -
  ACJWMD_RS10980 - 2305464..2305646 (-) 183 WP_002887313.1 hypothetical protein -
  ACJWMD_RS10985 - 2305661..2306326 (-) 666 WP_002887314.1 hypothetical protein -
  ACJWMD_RS10990 - 2306416..2306799 (-) 384 WP_411888493.1 hypothetical protein -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 73704.65 Da        Isoelectric Point: 7.6666

>NTDB_id=969897 ACJWMD_RS10960 WP_002887309.1 2300862..2302805(-) (clpE) [Streptococcus salivarius strain MRD6060]
MKERTNHNLSKTPYIDKYTTDLTEKIRPKRQDFVAWGRQDEIRQVFISLNRLEKNSPVLIGEAGVGKTAIVEGICADILN
KKAHVPTRFQGKQVKQLELSAIQGKEFDHTGKEVNIIAKMDGLIKEFMAHKDEFILFIDEVHTIMGTGVEGSALDVANSL
KPALSRGEIYLISATTADEFMIIERDPAMERRLQPVYVDELDKEASILVLKKRRPKYKRELDIEIPTDAIKAAVELSIRY
VTDKMLPDKAIDIIDEASATANIDGKSEITLKDIASVINRKKGIPMESLLRTSSTPVDFAEGMRAVVKGQDHVIRTIARL
MYKGIQGGQNKRRPLGTLLLLGTTGTGKTELAKQAAKQLFGSEEAMIRLDMSEYMTDNAVVRLIGNDERKGDLTEKIKKN
PYSLVLLDELEKAHPDVWALYLQMLDDGHLTDGRGRKINFKNTFIIATSNVGHKRIRDKYITSGQTFTEMNKTDYKEFMK
DMRDELIKIFKRPEFINRWKIEVTNILTKQTIDKIVYSKMAVHESSWFKEHHILINYEDVMDGEQTIDGKKYFYEYLSSV
GVSPEDGARPLERTIDEVLTDEIFEQLYFLGRKPQDYFIVDVSLSGYAPGTFAYGNSGRKTVQDRRQTHITVKRIPPEEY
GNYLLTS

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=969897 ACJWMD_RS10960 WP_002887309.1 2300862..2302805(-) (clpE) [Streptococcus salivarius strain MRD6060]
ATGAAGGAGAGGACTAACCATAATCTTAGTAAGACTCCTTATATTGACAAATACACAACAGACCTTACTGAGAAAATCAG
ACCCAAGCGTCAAGATTTTGTGGCTTGGGGTAGACAAGATGAAATCAGACAAGTCTTTATCTCACTGAATCGATTAGAAA
AAAACTCTCCTGTACTAATTGGTGAAGCTGGTGTAGGTAAAACAGCTATTGTAGAGGGAATTTGTGCGGATATTCTTAAC
AAGAAAGCCCACGTCCCAACACGTTTCCAAGGTAAGCAGGTTAAGCAACTAGAATTATCTGCTATCCAAGGGAAAGAATT
TGACCATACTGGTAAAGAGGTGAACATCATTGCCAAAATGGACGGATTGATTAAAGAGTTCATGGCTCATAAAGATGAGT
TTATCCTCTTTATTGATGAAGTGCATACCATTATGGGAACTGGGGTTGAGGGAAGTGCTCTTGACGTCGCTAATAGCTTG
AAACCAGCCTTATCTCGTGGGGAAATCTATCTTATTTCAGCCACTACAGCTGATGAGTTTATGATTATCGAACGAGATCC
AGCGATGGAACGACGTCTGCAACCAGTTTACGTTGATGAACTGGACAAAGAGGCATCTATTTTGGTCTTGAAAAAACGTC
GTCCCAAGTATAAACGAGAACTTGATATTGAGATTCCTACTGATGCCATTAAGGCAGCAGTAGAATTATCTATTCGTTAT
GTCACGGATAAAATGCTTCCGGATAAAGCTATTGATATTATTGATGAAGCTTCAGCGACTGCAAATATCGATGGGAAATC
AGAGATTACCTTAAAAGATATTGCGAGTGTCATAAACCGTAAAAAAGGTATTCCTATGGAAAGTCTACTACGCACGTCTT
CAACTCCAGTGGATTTTGCGGAAGGGATGCGTGCTGTTGTTAAGGGGCAAGACCATGTGATTCGAACTATAGCACGCCTT
ATGTATAAAGGTATTCAGGGTGGGCAGAACAAGCGAAGACCTCTAGGAACTCTTCTTCTACTTGGAACAACAGGTACAGG
TAAAACAGAATTGGCGAAACAAGCAGCAAAACAACTGTTTGGTAGTGAAGAAGCGATGATTCGGCTGGATATGTCAGAAT
ACATGACTGATAATGCCGTTGTTCGTCTTATAGGAAATGACGAGCGAAAAGGTGACTTAACGGAAAAAATTAAGAAGAAT
CCCTACTCGTTAGTACTATTGGATGAGTTAGAAAAGGCTCATCCAGATGTCTGGGCTTTGTATTTGCAAATGCTTGATGA
CGGGCATTTAACTGACGGACGTGGACGAAAAATCAATTTTAAGAATACGTTTATCATTGCAACATCAAACGTGGGGCACA
AGCGAATCAGAGATAAATATATCACCTCTGGTCAAACCTTTACAGAAATGAACAAGACTGACTATAAAGAGTTCATGAAG
GACATGAGAGACGAGTTAATCAAGATCTTTAAACGTCCTGAATTTATCAACCGTTGGAAAATTGAAGTGACTAATATCTT
GACGAAACAAACCATTGATAAGATTGTCTATTCAAAAATGGCTGTACATGAGAGCAGTTGGTTTAAAGAGCATCATATCC
TTATTAATTATGAGGATGTTATGGATGGTGAGCAAACTATCGATGGCAAAAAATATTTCTATGAATATCTCAGTAGTGTC
GGTGTTAGCCCAGAAGATGGAGCAAGGCCTTTAGAGAGAACTATTGATGAAGTGTTAACAGATGAAATCTTTGAGCAACT
GTATTTCCTTGGGCGAAAGCCACAAGATTACTTTATAGTTGACGTGTCTCTATCTGGATATGCACCAGGAACATTTGCGT
ATGGGAACTCAGGTAGAAAGACAGTTCAAGATCGGCGTCAGACTCATATTACTGTCAAACGGATACCTCCAGAGGAGTAT
GGTAACTATTTGCTTACTTCTTAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(203-282)

AAA domain (Cdc48 subfamily) (AAA_2)

(333-500)

ATPase family associated with various cellular activities (AAA) (AAA)

(58-183)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(551-588)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

37.757

97.836

0.369
  clpE Streptococcus pneumoniae TIGR4

37.246

98.764

0.368
  clpE Streptococcus pneumoniae Rx1

37.246

98.764

0.368
  clpE Streptococcus pneumoniae D39

37.246

98.764

0.368
  clpE Streptococcus pneumoniae R6

37.246

98.764

0.368
  clpC Lactococcus lactis subsp. cremoris KW2

37.066

97.991

0.363