Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   MHB78_RS15050 Genome accession   NZ_CP150286
Coordinates   2821345..2822124 (-) Length   259 a.a.
NCBI ID   WP_006638180.1    Uniprot ID   A0A6I7F231
Organism   Bacillus sp. FSL K6-0138     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2801478..2825052 2821345..2822124 within 0


Gene organization within MGE regions


Location: 2801478..2825052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MHB78_RS14930 (MHB78_14930) flhF 2801478..2802590 (-) 1113 WP_046128946.1 flagellar biosynthesis protein FlhF -
  MHB78_RS14935 (MHB78_14935) flhA 2802587..2804623 (-) 2037 WP_046128947.1 flagellar biosynthesis protein FlhA -
  MHB78_RS14940 (MHB78_14940) flhB 2804654..2805733 (-) 1080 WP_046128948.1 flagellar biosynthesis protein FlhB -
  MHB78_RS14945 (MHB78_14945) fliR 2805730..2806515 (-) 786 WP_099047037.1 flagellar biosynthetic protein FliR -
  MHB78_RS14950 (MHB78_14950) fliQ 2806517..2806786 (-) 270 WP_046128950.1 flagellar biosynthesis protein FliQ -
  MHB78_RS14955 (MHB78_14955) fliP 2806801..2807466 (-) 666 WP_046128951.1 flagellar type III secretion system pore protein FliP -
  MHB78_RS14960 (MHB78_14960) fliZ 2807459..2808127 (-) 669 WP_046129017.1 flagella biosynthesis regulatory protein FliZ -
  MHB78_RS14965 (MHB78_14965) - 2808143..2808505 (-) 363 WP_003181796.1 response regulator -
  MHB78_RS14970 (MHB78_14970) fliY 2808534..2809661 (-) 1128 WP_046128952.1 flagellar motor switch phosphatase FliY -
  MHB78_RS14975 (MHB78_14975) fliM 2809651..2810649 (-) 999 WP_046128953.1 flagellar motor switch protein FliM -
  MHB78_RS14980 (MHB78_14980) fliL 2810688..2811119 (-) 432 WP_046128954.1 flagellar basal body-associated protein FliL -
  MHB78_RS14985 (MHB78_14985) - 2811116..2811331 (-) 216 WP_046128955.1 flagellar FlbD family protein -
  MHB78_RS14990 (MHB78_14990) flgG 2811376..2812173 (-) 798 WP_046128956.1 flagellar basal body rod protein FlgG -
  MHB78_RS14995 (MHB78_14995) flgD 2812202..2812639 (-) 438 WP_046128957.1 flagellar hook assembly protein FlgD -
  MHB78_RS15000 (MHB78_15000) - 2812639..2814015 (-) 1377 WP_046128958.1 flagellar hook-length control protein FliK -
  MHB78_RS15005 (MHB78_15005) - 2814034..2814627 (-) 594 WP_046128959.1 MotE family protein -
  MHB78_RS15010 (MHB78_15010) fliJ 2814640..2815083 (-) 444 WP_046128960.1 flagellar export protein FliJ -
  MHB78_RS15015 (MHB78_15015) fliI 2815086..2816399 (-) 1314 WP_046128961.1 flagellar protein export ATPase FliI -
  MHB78_RS15020 (MHB78_15020) fliH 2816399..2817166 (-) 768 WP_052948478.1 flagellar assembly protein FliH -
  MHB78_RS15025 (MHB78_15025) fliG 2817150..2818166 (-) 1017 WP_046128963.1 flagellar motor switch protein FliG -
  MHB78_RS15030 (MHB78_15030) fliF 2818180..2819781 (-) 1602 WP_046128964.1 flagellar basal-body MS-ring/collar protein FliF -
  MHB78_RS15035 (MHB78_15035) fliE 2819832..2820149 (-) 318 WP_065894398.1 flagellar hook-basal body complex protein FliE -
  MHB78_RS15040 (MHB78_15040) flgC 2820162..2820614 (-) 453 WP_046128966.1 flagellar basal body rod protein FlgC -
  MHB78_RS15045 (MHB78_15045) flgB 2820614..2821003 (-) 390 WP_046128967.1 flagellar basal body rod protein FlgB -
  MHB78_RS15050 (MHB78_15050) codY 2821345..2822124 (-) 780 WP_006638180.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  MHB78_RS15055 (MHB78_15055) hslU 2822162..2823574 (-) 1413 WP_269081991.1 HslU--HslV peptidase ATPase subunit -
  MHB78_RS15060 (MHB78_15060) hslV 2823582..2824124 (-) 543 WP_046128969.1 ATP-dependent protease subunit HslV -
  MHB78_RS15065 (MHB78_15065) xerC 2824138..2825052 (-) 915 WP_046128970.1 tyrosine recombinase XerC -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 29087.45 Da        Isoelectric Point: 4.8196

>NTDB_id=969553 MHB78_RS15050 WP_006638180.1 2821345..2822124(-) (codY) [Bacillus sp. FSL K6-0138]
MALLQKTRKINAMLQNAAGKPVNFKEMAETLRDVIDSNIFVVSRRGKLLGFSINQQIENDRMKKMLEERQFPEDYTKSLF
NIPETSSNLDINSEYTAFPVENRDLFQAGLTTIVPIIGGGERLGTLILSRLQEKFEDDDLILAEYGATVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELDGNEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNNKFLMELEKLKSH

Nucleotide


Download         Length: 780 bp        

>NTDB_id=969553 MHB78_RS15050 WP_006638180.1 2821345..2822124(-) (codY) [Bacillus sp. FSL K6-0138]
ATGGCTTTATTACAAAAAACAAGAAAGATTAATGCAATGCTGCAAAATGCGGCAGGGAAGCCGGTTAATTTCAAAGAAAT
GGCCGAAACGCTTCGCGATGTAATTGATTCGAACATTTTCGTCGTCAGCCGCAGAGGAAAACTTCTCGGCTTCTCTATCA
ACCAGCAGATCGAAAACGACCGGATGAAAAAAATGCTTGAAGAACGCCAGTTCCCTGAGGATTACACAAAAAGCCTGTTC
AACATTCCGGAAACATCATCAAACCTCGACATTAACAGCGAATACACGGCGTTCCCTGTCGAAAACCGCGATCTTTTCCA
AGCAGGGTTGACAACGATCGTACCGATCATCGGCGGAGGTGAAAGACTCGGAACATTGATTCTTTCCCGTCTTCAGGAAA
AATTTGAAGATGATGATCTGATCCTTGCCGAATATGGCGCAACTGTCGTCGGAATGGAGATTCTCAGAGAGAAAGCCGAA
GAAATCGAAGAGGAAGCCCGCAGCAAGGCTGTCGTTCAAATGGCGATCAGTTCATTATCTTACAGCGAGCTTGAAGCGAT
TGAACATATCTTCGAGGAGCTCGATGGGAACGAAGGCCTGCTCGTTGCAAGTAAAATTGCAGACCGCGTCGGCATTACGC
GCTCGGTTATCGTAAATGCGCTGAGAAAACTCGAAAGCGCAGGCGTTATTGAGTCCCGCTCATTAGGGATGAAAGGCACA
TACATTAAAGTGCTGAACAACAAGTTCCTGATGGAGCTTGAAAAACTAAAGTCTCATTAA

Domains

Predicted by InterproScan.

CodY helix-turn-helix domain (HTH_CodY)

(198-255)

CodY GAF-like domain (CodY)

(3-178)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I7F231

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

94.981

100

0.95
  codY Lactococcus lactis subsp. lactis strain DGCC12653

47.451

98.456

0.467

Multiple sequence alignment