Detailed information NTG0969488

Bioinformatically predicted

Overview

• Name: priA
• Type: Machinery gene
• Locus tag: ACJVC4_RS07370
• Genome accession: NZ_CP177179
• Coordinates: 1606369..1608765 (-)
• Length: 798 a.a.
• NCBI ID: WP_002891426.1
• Uniprot ID: J7SHP6
• Organism: Streptococcus salivarius strain MRD-NRLLH
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1601369..1613765

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJVC4_RS07350	stkP/pknB	1601449..1603323 (-)	1875	WP_002891421.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator
ACJVC4_RS07355	-	1603323..1604060 (-)	738	WP_037598574.1	Stp1/IreP family PP2C-type Ser/Thr phosphatase	-
ACJVC4_RS07360	rsmB	1604104..1605426 (-)	1323	WP_037598576.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
ACJVC4_RS07365	fmt	1605416..1606351 (-)	936	WP_002891425.1	methionyl-tRNA formyltransferase	-
ACJVC4_RS07370	priA	1606369..1608765 (-)	2397	WP_002891426.1	primosomal protein N'	Machinery gene
ACJVC4_RS07375	rpoZ	1608908..1609222 (-)	315	WP_002886855.1	DNA-directed RNA polymerase subunit omega	-
ACJVC4_RS07380	gmk	1609244..1609873 (-)	630	WP_002884259.1	guanylate kinase	-
ACJVC4_RS07385	ftsY	1610108..1611508 (-)	1401	WP_002891427.1	signal recognition particle-docking protein FtsY	-
ACJVC4_RS07390	-	1611519..1612337 (-)	819	WP_002891428.1	Cof-type HAD-IIB family hydrolase	-
ACJVC4_RS07395	-	1612330..1613124 (-)	795	WP_002891429.1	HAD-IIB family hydrolase	-
ACJVC4_RS07400	-	1613306..1613683 (+)	378	WP_002891430.1	GntR family transcriptional regulator	-

Sequence

Protein

• Length: 798 a.a.
• Molecular weight: 90950.34 Da
• Isoelectric Point: 6.8114

>NTDB_id=969488 ACJVC4_RS07370 WP_002891426.1 1606369..1608765(-) (priA) [Streptococcus salivarius strain MRD-NRLLH]
MVLVAHIIVDVPLMQTDRPYSYLVPEAMQEQIAIGMRVHVPFGKGNRLLQGFIIGLEEQENLRDFPELKPIAELLDYEPV
LNQEQLDLANQMRHTVFSYKISILKSMLPGLLNSQYDKVIMATDKLGEEEKATLLQGQNHILFSQLSEVQRQAIPRLVQS
GRVTVDYLAKDKQNIKTEKHYSVQKGILETLAISQRAKKRLELRDFLLEKSESGKLTDLHKLFSRDVVKFFIEAGALVIT
EVEVNRADSYFEKVEKTDFLELNAQQAHAVEEMTCQIGQGGKPFLLEGVTGSGKTEVYLHLIERTLAMRKTAIVLVPEIS
LTPQMTNRFISRFGDLVAIMHSGLSDGEKFDEWRKVKSGQAKVVVGARSAIFAPLDNIGAIIIDEEHEATYKQESNPRYH
ARDVALLRARSHGAVLVLGSATPSVETRARAQKGVYHFLELTQRANPNAKIPQVEVVDFKDFVGRQEASDFTPPLLEKIR
ERLARKEQVVLMLNRRGYSSFVMCRDCGYVDDCPNCDISLTLHMDTKTMNCHYCDFQKAIPHVCPNCQSRQIRYYGTGTQ
KAYDQLTELLPEARVIRMDVDTTRKKGAHEKLLETFGNGKADILLGTQMIAKGLDFPNVTLVGVLNADTSLNLPDFRSAE
RTFQLLTQVAGRAGRADKEGEVIIQTYNPSHYAIRFAQQQDYEAFYAYEMGIRRQLAYPPYFYTVGITLSHKDEEFVVRK
SYEVMAYLRECLSDKVTFLGPTPKPIARTHNLYHYQIIIKYRFEDNLEETLNRVLDMTQEPENKDLRLIIDHEPQNFT

Nucleotide

• Length: 2397 bp

>NTDB_id=969488 ACJVC4_RS07370 WP_002891426.1 1606369..1608765(-) (priA) [Streptococcus salivarius strain MRD-NRLLH]
ATGGTTTTAGTAGCACATATTATTGTCGACGTTCCTCTGATGCAGACGGACAGACCTTATAGTTACCTGGTACCGGAAGC
CATGCAAGAACAAATCGCCATCGGTATGCGGGTTCATGTGCCTTTTGGTAAAGGAAATCGTTTACTTCAAGGTTTTATTA
TTGGCTTGGAAGAGCAGGAAAATTTAAGAGATTTTCCTGAACTAAAACCCATCGCTGAGCTTTTAGATTATGAGCCAGTG
CTTAATCAGGAACAGCTGGATTTGGCTAATCAGATGCGACATACGGTCTTTTCTTATAAGATTTCCATCTTGAAGTCAAT
GCTACCCGGTCTCCTTAATTCGCAGTACGATAAGGTTATCATGGCAACTGATAAACTGGGTGAAGAGGAAAAAGCGACTC
TCCTTCAAGGGCAGAATCATATTCTTTTCTCGCAGTTGTCAGAGGTACAACGTCAAGCCATTCCTCGTCTGGTCCAGTCT
GGGCGTGTAACGGTTGATTACCTTGCTAAAGATAAGCAGAATATTAAGACTGAGAAGCACTATAGTGTTCAAAAGGGGAT
TCTCGAGACTTTGGCAATTTCGCAAAGGGCTAAGAAACGATTGGAGTTGCGAGACTTCTTGCTAGAAAAGAGTGAGTCTG
GCAAGTTGACGGATCTCCACAAGCTTTTTTCACGAGATGTGGTTAAGTTTTTCATTGAAGCTGGTGCCTTGGTCATCACC
GAAGTTGAGGTCAATCGTGCCGATAGCTACTTTGAAAAGGTAGAAAAGACAGATTTTCTTGAGCTTAATGCCCAACAGGC
GCATGCGGTTGAAGAAATGACGTGCCAAATTGGACAAGGTGGCAAACCTTTCTTATTGGAAGGAGTGACGGGATCAGGTA
AGACCGAGGTCTACCTGCATCTTATCGAGAGGACCCTGGCTATGAGAAAAACCGCCATTGTCTTGGTGCCAGAGATTTCC
CTAACACCCCAAATGACCAATCGCTTCATTTCACGTTTTGGTGACTTGGTGGCGATTATGCATTCAGGCTTGTCAGACGG
TGAGAAATTTGACGAGTGGCGTAAGGTTAAATCTGGTCAGGCCAAGGTTGTGGTAGGAGCGCGTTCGGCTATCTTTGCTC
CTTTGGACAATATCGGGGCAATCATTATCGATGAGGAACATGAGGCTACTTATAAACAAGAGTCCAATCCTCGCTATCAT
GCTAGAGATGTTGCCTTGCTGAGGGCTAGGAGTCATGGAGCTGTGCTTGTCCTTGGGTCAGCAACACCCTCTGTTGAGAC
ACGGGCGAGAGCTCAGAAAGGGGTTTACCATTTTCTTGAGTTGACACAAAGGGCTAATCCTAATGCTAAAATTCCGCAGG
TGGAAGTGGTGGACTTCAAGGATTTTGTGGGCCGTCAAGAGGCGAGTGATTTTACGCCACCTCTTTTGGAAAAAATCAGG
GAACGTTTGGCACGTAAGGAACAAGTCGTATTGATGTTAAACCGTCGTGGGTATTCCTCTTTTGTCATGTGTCGTGACTG
TGGCTATGTAGATGATTGTCCCAATTGTGATATTTCACTGACCTTGCACATGGATACCAAGACCATGAATTGCCACTATT
GTGATTTTCAAAAAGCAATACCACATGTCTGCCCTAACTGTCAGAGTCGTCAGATTCGCTATTATGGGACTGGGACACAG
AAGGCCTATGATCAATTGACGGAACTCTTGCCAGAAGCCAGAGTGATTCGTATGGATGTTGATACGACACGTAAGAAAGG
TGCTCACGAGAAACTCTTAGAGACTTTTGGAAATGGCAAGGCTGACATTTTGCTTGGGACTCAGATGATTGCCAAGGGAT
TGGATTTTCCCAATGTCACCTTGGTAGGGGTCTTGAATGCAGATACATCGCTTAATTTACCAGATTTTCGTTCGGCTGAG
CGTACCTTCCAGCTTTTGACTCAGGTGGCTGGTCGTGCTGGTCGTGCTGACAAGGAAGGGGAAGTTATTATTCAAACCTA
TAATCCTAGTCATTATGCCATTCGGTTTGCGCAACAACAGGATTATGAAGCTTTCTATGCCTATGAGATGGGGATTCGAC
GTCAGTTGGCCTATCCGCCATATTTTTATACGGTAGGAATCACGCTTTCTCACAAGGATGAAGAGTTTGTCGTCCGCAAG
AGCTATGAGGTTATGGCTTATTTAAGAGAGTGCTTGTCAGACAAGGTGACCTTCCTAGGGCCAACGCCTAAGCCTATTGC
CCGAACACATAACCTTTATCATTATCAGATTATTATCAAATACCGTTTTGAGGATAACTTGGAAGAGACGCTTAATAGGG
TCCTTGACATGACTCAGGAACCTGAAAACAAGGACCTGCGTTTGATTATCGATCACGAACCTCAGAATTTTACCTAA

Domains

Predicted by InterProScan.

• Helicase conserved C-terminal domain (Helicase_C) (567-656)

• Primosomal protein N C-terminal domain (PriA_C) (700-794)

• 3DNA-binding domain (3BD) (PriA_3primeBD) (7-109)

• PriA DNA helicase Cys-rich region (CRR) domain (Zn_ribbon_PriA) (513-538)

• Type III restriction enzyme, res subunit (ResIII) (260-423)

3D structure

• AlphaFold DB: J7SHP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
priA	Bacillus subtilis subsp. subtilis str. 168	48.139	100	0.486