Detailed information NTG0967764

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ACKZ7U_RS06525
• Genome accession: NZ_CP176568
• Coordinates: 1293559..1294332 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain IMT39173
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1288559..1299332

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACKZ7U_RS06505 (ACKZ7U_06505)	trmFO	1288903..1290210 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ACKZ7U_RS06510 (ACKZ7U_06510)	xerC	1290627..1291523 (+)	897	WP_001015602.1	tyrosine recombinase XerC	-
ACKZ7U_RS06515 (ACKZ7U_06515)	hslV	1291520..1292065 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ACKZ7U_RS06520 (ACKZ7U_06520)	hslU	1292131..1293534 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
ACKZ7U_RS06525 (ACKZ7U_06525)	codY	1293559..1294332 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ACKZ7U_RS06530 (ACKZ7U_06530)	-	1294383..1294475 (+)	93	WP_031788481.1	hypothetical protein	-
ACKZ7U_RS06535 (ACKZ7U_06535)	rpsB	1294674..1295441 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
ACKZ7U_RS06540 (ACKZ7U_06540)	-	1295475..1295588 (+)	114	WP_001789890.1	hypothetical protein	-
ACKZ7U_RS06545 (ACKZ7U_06545)	tsf	1295623..1296504 (+)	882	WP_000201387.1	translation elongation factor Ts	-
ACKZ7U_RS06550 (ACKZ7U_06550)	pyrH	1296641..1297363 (+)	723	WP_000057330.1	UMP kinase	-
ACKZ7U_RS06555 (ACKZ7U_06555)	frr	1297382..1297936 (+)	555	WP_001280006.1	ribosome recycling factor	-
ACKZ7U_RS06560 (ACKZ7U_06560)	-	1298309..1299079 (+)	771	WP_000473705.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=967764 ACKZ7U_RS06525 WP_000055337.1 1293559..1294332(+) (codY) [Staphylococcus aureus strain IMT39173]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=967764 ACKZ7U_RS06525 WP_000055337.1 1293559..1294332(+) (codY) [Staphylococcus aureus strain IMT39173]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATCCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTTCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428