Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   NHP_RS03650 Genome accession   NZ_AP026684
Coordinates   690137..692482 (-) Length   781 a.a.
NCBI ID   WP_015106431.1    Uniprot ID   A0A0K2Y873
Organism   Helicobacter heilmannii strain     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 685137..697482
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NHP_RS03630 (ASB1_07630) - 685495..685857 (-) 363 WP_053827790.1 hypothetical protein -
  NHP_RS03635 (ASB1_07640) - 686014..687798 (-) 1785 WP_015106434.1 DUF262 domain-containing protein -
  NHP_RS03640 (ASB1_07650) coaBC 687891..689120 (-) 1230 WP_015106433.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  NHP_RS03645 (ASB1_07660) pseB 689110..690099 (-) 990 WP_015106432.1 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) -
  NHP_RS03650 (ASB1_07670) comB4 690137..692482 (-) 2346 WP_015106431.1 hypothetical protein Machinery gene
  NHP_RS03655 (ASB1_07680) - 692491..692886 (-) 396 WP_265341715.1 polysaccharide lyase beta-sandwich domain-containing protein -
  NHP_RS03660 (ASB1_07690) - 692904..694559 (-) 1656 WP_265341716.1 polysaccharide lyase family 8 super-sandwich domain-containing protein -
  NHP_RS03665 (ASB1_07700) - 694897..695148 (-) 252 WP_015106428.1 NAD(P)H-dependent oxidoreductase -

Sequence

Protein


Download         Length: 781 a.a.        Molecular weight: 87660.67 Da        Isoelectric Point: 7.9347

>NTDB_id=96667 NHP_RS03650 WP_015106431.1 690137..692482(-) (comB4) [Helicobacter heilmannii strain]
MKFGLEFWRHKALDLLAGALPKTHSMVEENNILGLYNERFLFTKSEQLVGLLNIKGLSANTLLQEDLQTHFSSKQNALEQ
LEGVVLRIHTKRAKVQLEPPKKPPNPQVQALLDLSQPKDLYENTYTLIFETTQNPLKDFLEQKKLELTTSAQAHQHLAQH
LSACMEQMAHALSAFKPTPLSAKEALNFYATFINGHPTSLNPTLGFLEDSYIATNIHFNKDHYIQEHATHTTYNRILGVK
AYASKTLSSLALLSLLHQELACEVFLSLEPLSTQVALAFVQEKIRLSFARLVRQELQSYYEQIQAKRLRLQKAALNIILK
APDLKSLDHHTKEVLSVLSNARLVGVVETLGLRPAYFSLFPGRLHLNPRLRCQSAQALATLMLFEKPNCGFKSNPWGNQP
LSVFKNLDHSPYLFNFHNQESTPSPTSPRTNGHTMIIGATGAGKTTLMGFLMANALKYDKLNILALDRAYGLFSCINYFG
GVYNSGKDFKINPLTLELTPSNQDFLHSFYSSLCHLSSHPQNKEDIHASHALLKALKSLHATLPQKSFHLQDFKEAITNA
PTLHLSLEPYLQNPLFNALEDSLEFDTPLVAINMDAISANPKDLGLLAYYIFYKILHRALEKQEGFLLFVDEFKSYAANE
TINTHINTLITQARKANGVVVLALQDTNQLASIPEAASFVKNMGTLIFYPQKHLDSTRLSQDLGIQLSYMEAHFLENTPL
SAQQVLVKNMAEGSSNIIHVGLQGLGAHLNIFNSNAAHVKRLQTLMQAYPETWREVLLQEG

Nucleotide


Download         Length: 2346 bp        

>NTDB_id=96667 NHP_RS03650 WP_015106431.1 690137..692482(-) (comB4) [Helicobacter heilmannii strain]
TTGAAATTTGGCCTAGAGTTTTGGCGGCATAAAGCCCTAGACCTCTTGGCCGGCGCGTTGCCAAAAACCCACTCCATGGT
GGAAGAGAACAACATTCTAGGGCTTTACAACGAACGCTTTTTATTCACCAAGAGCGAGCAGCTCGTGGGGCTCTTAAATA
TCAAGGGTTTAAGCGCAAATACACTCTTGCAAGAGGACTTGCAAACCCACTTTTCTAGCAAGCAGAACGCTCTAGAGCAG
TTAGAGGGCGTGGTGCTTCGTATCCACACCAAGCGCGCCAAAGTCCAGCTAGAGCCCCCCAAAAAGCCCCCCAACCCCCA
AGTGCAAGCCCTATTAGACTTATCCCAGCCCAAGGACTTATACGAGAACACCTACACGCTCATTTTTGAAACCACGCAAA
ACCCCCTAAAAGACTTCTTAGAGCAGAAAAAACTAGAACTCACCACCAGCGCACAGGCGCACCAGCATCTAGCCCAGCAT
TTGAGTGCATGCATGGAGCAAATGGCGCACGCTCTAAGTGCCTTTAAACCCACCCCTCTAAGTGCCAAAGAAGCCCTAAA
CTTTTACGCCACTTTCATCAACGGACACCCCACAAGCTTAAACCCCACACTAGGTTTTTTAGAAGACAGCTACATCGCCA
CGAACATCCACTTCAACAAAGACCACTACATCCAAGAGCACGCCACTCACACGACCTATAACCGCATTTTGGGCGTGAAA
GCCTATGCAAGCAAGACTTTAAGCTCGCTCGCCCTACTCTCCTTGTTGCATCAAGAGCTCGCGTGTGAAGTGTTTTTAAG
CCTTGAGCCCTTAAGCACCCAAGTGGCCCTAGCCTTCGTACAGGAGAAAATCCGCCTGAGTTTTGCCCGCCTTGTGCGCC
AAGAACTACAAAGTTATTACGAGCAGATCCAAGCCAAACGCTTGCGCTTGCAAAAAGCCGCCTTGAATATCATTCTCAAA
GCCCCCGATTTAAAGAGCCTAGATCACCATACCAAGGAAGTTCTAAGCGTACTCTCTAACGCCCGCTTGGTGGGGGTGGT
GGAGACCTTGGGGCTAAGGCCGGCTTACTTTTCTTTATTTCCCGGGCGTTTGCATTTAAACCCCCGTTTGCGTTGCCAAA
GTGCACAGGCCCTAGCCACGCTCATGCTCTTTGAAAAGCCAAATTGTGGCTTTAAAAGCAATCCGTGGGGCAACCAGCCC
TTAAGCGTGTTTAAGAATTTAGACCACTCCCCCTATCTCTTCAACTTCCACAACCAAGAGAGCACCCCAAGCCCCACCAG
CCCCCGCACCAACGGGCACACCATGATTATTGGGGCAACGGGGGCGGGCAAGACGACCTTAATGGGCTTTTTAATGGCAA
ATGCGCTCAAATACGACAAGCTGAATATCCTGGCCCTTGATCGCGCCTATGGGCTGTTTTCGTGTATTAATTACTTTGGC
GGGGTGTATAACTCGGGCAAGGATTTTAAAATCAACCCCCTAACTTTAGAGCTCACGCCCAGCAACCAAGACTTTTTACA
CAGCTTTTACTCTAGCTTATGTCATCTCTCTTCTCACCCACAAAATAAGGAAGACATCCACGCCAGTCACGCCCTTTTAA
AAGCCCTAAAAAGTCTGCATGCCACTTTGCCACAAAAGAGCTTTCATCTGCAAGATTTCAAAGAGGCCATCACGAATGCC
CCCACTTTGCACCTAAGTCTAGAGCCCTACTTGCAAAATCCCCTTTTTAACGCCCTAGAAGACAGCCTAGAGTTTGACAC
CCCGCTAGTCGCCATCAACATGGATGCGATCAGTGCCAACCCTAAAGATTTAGGGCTTTTGGCGTACTACATTTTCTATA
AAATCCTGCATAGAGCCCTAGAAAAGCAAGAGGGCTTTTTGCTCTTTGTGGATGAGTTTAAAAGCTACGCTGCCAATGAA
ACCATAAACACCCACATCAACACCTTGATCACCCAGGCTAGAAAGGCCAATGGGGTAGTGGTGCTCGCCTTGCAAGATAC
AAACCAGCTTGCTAGCATCCCCGAGGCAGCCAGCTTTGTTAAAAACATGGGAACTTTGATTTTCTACCCCCAAAAGCACT
TAGACAGCACCCGTTTAAGCCAAGATTTAGGCATCCAGTTAAGCTACATGGAGGCGCATTTTTTAGAAAACACCCCCTTA
AGCGCACAACAAGTTTTAGTCAAAAACATGGCAGAGGGCAGCTCGAACATCATCCATGTGGGTTTGCAGGGCTTGGGGGC
GCATTTAAACATCTTCAACTCCAACGCCGCCCATGTCAAACGGCTACAAACCCTCATGCAAGCTTACCCAGAGACTTGGC
GGGAAGTCTTGTTGCAAGAGGGCTAA

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(172-369)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K2Y873

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

49.296

100

0.493

Multiple sequence alignment