Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   QMM33_RS08220 Genome accession   NZ_AP025940
Coordinates   1643070..1643729 (+) Length   219 a.a.
NCBI ID   WP_000565607.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700204     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1638070..1648729
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMM33_RS08200 (PC0204_16140) - 1638707..1639603 (-) 897 WP_281737525.1 haloacid dehalogenase-like hydrolase -
  QMM33_RS08205 (PC0204_16150) - 1639606..1640868 (-) 1263 WP_000413334.1 PTS sugar transporter subunit IIC -
  QMM33_RS08210 (PC0204_16160) - 1641148..1642326 (+) 1179 WP_000175874.1 ROK family transcriptional regulator -
  QMM33_RS08215 (PC0204_16170) - 1642554..1643000 (-) 447 WP_000155419.1 GNAT family N-acetyltransferase -
  QMM33_RS08220 (PC0204_16180) cclA/cilC 1643070..1643729 (+) 660 WP_000565607.1 A24 family peptidase Machinery gene
  QMM33_RS08225 (PC0204_16190) - 1643781..1644932 (-) 1152 WP_000481744.1 XRE family transcriptional regulator -
  QMM33_RS08230 (PC0204_16200) - 1644947..1645678 (-) 732 WP_000934017.1 hypothetical protein -
  QMM33_RS08235 - 1645907..1646008 (+) 102 Protein_1634 prepilin peptidase -
  QMM33_RS08240 (PC0204_16210) trpA 1645980..1646756 (-) 777 WP_001126993.1 tryptophan synthase subunit alpha -
  QMM33_RS08245 (PC0204_16220) trpB 1646749..1647972 (-) 1224 WP_000331283.1 tryptophan synthase subunit beta -
  QMM33_RS08250 (PC0204_16230) - 1647950..1648549 (-) 600 WP_000169895.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24826.93 Da        Isoelectric Point: 7.3241

>NTDB_id=95522 QMM33_RS08220 WP_000565607.1 1643070..1643729(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700204]
MIDIYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLHPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=95522 QMM33_RS08220 WP_000565607.1 1643070..1643729(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700204]
ATGATTGATATTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCATCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae Rx1

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae D39

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae R6

96.347

100

0.963
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

86.758

100

0.868

Multiple sequence alignment