Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   WA132_RS11955 Genome accession   NZ_CP146939
Coordinates   2511876..2513000 (+) Length   374 a.a.
NCBI ID   WP_000228517.1    Uniprot ID   E2QFE2
Organism   Escherichia coli strain 2A     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2506876..2518000
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WA132_RS11930 (WA132_11930) mscL 2506999..2507412 (-) 414 WP_000022445.1 large-conductance mechanosensitive channel protein MscL -
  WA132_RS11935 (WA132_11935) trkA 2507542..2508918 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  WA132_RS11940 (WA132_11940) rsmB 2508940..2510229 (-) 1290 WP_001765229.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  WA132_RS11945 (WA132_11945) fmt 2510275..2511222 (-) 948 WP_001765230.1 methionyl-tRNA formyltransferase -
  WA132_RS11950 (WA132_11950) def 2511237..2511746 (-) 510 WP_000114984.1 peptide deformylase -
  WA132_RS11955 (WA132_11955) dprA 2511876..2513000 (+) 1125 WP_000228517.1 DNA-protecting protein DprA Machinery gene
  WA132_RS11960 (WA132_11960) smg 2512972..2513445 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  WA132_RS11965 (WA132_11965) yrdD 2513474..2514016 (+) 543 WP_001312137.1 type I DNA topoisomerase -
  WA132_RS11970 (WA132_11970) tsaC 2514021..2514593 (+) 573 WP_001765231.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  WA132_RS11975 (WA132_11975) aroE 2514598..2515416 (+) 819 WP_001765233.1 shikimate dehydrogenase -
  WA132_RS11980 (WA132_11980) yrdB 2515413..2515670 (+) 258 WP_001765234.1 DUF1488 domain-containing protein -
  WA132_RS11985 (WA132_11985) yrdA 2515646..2516200 (-) 555 WP_001525792.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40910.86 Da        Isoelectric Point: 6.0395

>NTDB_id=945110 WA132_RS11955 WP_000228517.1 2511876..2513000(+) (dprA) [Escherichia coli strain 2A]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=945110 WA132_RS11955 WP_000228517.1 2511876..2513000(+) (dprA) [Escherichia coli strain 2A]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGCCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (DprA_WH)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Vibrio cholerae strain A1552

49.355

82.888

0.409
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Haemophilus influenzae Rd KW20

44.214

90.107

0.398
  dprA Legionella pneumophila strain ERS1305867

44.242

88.235

0.39