Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   V9W64_RS09400 Genome accession   NZ_CP146598
Coordinates   1995210..1997435 (+) Length   741 a.a.
NCBI ID   WP_274584918.1    Uniprot ID   A0A9X4IAU1
Organism   Neisseria leonii strain 51.81     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 1990210..2002435
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V9W64_RS09380 (V9W64_09380) - 1991025..1991609 (-) 585 WP_274570986.1 aminodeoxychorismate/anthranilate synthase component II -
  V9W64_RS09385 (V9W64_09385) typA 1991890..1993698 (-) 1809 WP_274584917.1 translational GTPase TypA -
  V9W64_RS09390 (V9W64_09390) bfr 1994129..1994593 (+) 465 WP_274572144.1 bacterioferritin -
  V9W64_RS09395 (V9W64_09395) bfr 1994620..1995093 (+) 474 WP_274572233.1 bacterioferritin -
  V9W64_RS09400 (V9W64_09400) comA 1995210..1997435 (+) 2226 WP_274584918.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  V9W64_RS09405 (V9W64_09405) - 1997625..1999322 (+) 1698 WP_274584919.1 TolC family protein -
  V9W64_RS09410 (V9W64_09410) - 1999329..2001560 (+) 2232 WP_274584920.1 type I secretion system permease/ATPase -

Sequence

Protein


Download         Length: 741 a.a.        Molecular weight: 80436.53 Da        Isoelectric Point: 10.2971

>NTDB_id=943273 V9W64_RS09400 WP_274584918.1 1995210..1997435(+) (comA) [Neisseria leonii strain 51.81]
MRRYLAAWPTGVLLSFGLADIPPLWLWTAAAVLLLSAALRFRRLRPLPVLLAGAAFAVWQVQTALDGQWPAERQGREVLL
VRVADLPQTDGRRTVFAADAWTEDKRYYRLRLSDYEGRDWPAGSYWRVSARLRPPVGEVNLRGFNREAWALANGLAGIGS
VGAARTAVDAEKRPFSDGLAAVRTAISLRWQRWYGQGADNGVALMRALSVGEQGALSDEMWQVLRPLGLNHLVSISGLHV
SMVALLAAVFGRVLLKYGPHTPKRPRLWLLTVGLAAAWAYAALAGFAVPTVRAAAMLTVVALAWARGGTASAWTAWWAAL
AGVLTLWPTAVLAAGTWLSFGLVGALLWGGSWRTGEQGGGLWRAQWAAGMMSAVMLGYGFAVLPLWSPAVNLPAIPWFSW
VLVPLALAASAIPWPPLQQAAVWLGEYTWRALAWLAEYAPEWSVAAAPWPLAAAAFCAVAVWLVPAGLGLRPWAAAVLLL
FVLYRPERPPSGRLNVTVLDSGQGLAVWLQTANRDLLFDTGTAAAAGGQVIPALRAAGVRRLDTLVFSHRDNDHDGGGQM
VRQAFAPDRVWAGQPEFYSGARHCSPASWQWDGVHFEWLTPEESADSDNGKSCVLRAVAGGEAVLLTGDLDSRGEQRLIA
QYGSALFSQLLILGHHGSNTSSAGRFLNLVSPEYAVASSGYANAYGHPSPAVQNRVRAHGGRLLRTDLSGAWRFELGTGQ
RLPVQVRPWRPYWQKKPFDWV

Nucleotide


Download         Length: 2226 bp        

>NTDB_id=943273 V9W64_RS09400 WP_274584918.1 1995210..1997435(+) (comA) [Neisseria leonii strain 51.81]
ATGCGGCGGTATCTGGCGGCGTGGCCGACGGGGGTGTTGTTGTCGTTCGGTTTGGCGGACATACCGCCGCTTTGGCTGTG
GACGGCCGCCGCCGTGTTGCTGCTGTCTGCCGCTTTGCGCTTCCGCCGCCTGAGGCCGCTGCCCGTTTTGCTGGCCGGAG
CGGCGTTTGCGGTGTGGCAGGTTCAGACGGCCTTGGACGGGCAATGGCCGGCGGAGCGGCAAGGGCGGGAAGTGTTGCTG
GTGCGGGTGGCGGACTTGCCGCAAACCGACGGGCGGCGGACGGTGTTTGCCGCCGACGCGTGGACGGAGGACAAGCGGTA
TTACCGTCTGCGCTTGTCGGATTATGAGGGGCGCGACTGGCCGGCGGGCAGCTATTGGCGGGTATCGGCGCGTTTGCGCC
CGCCGGTGGGCGAAGTGAATTTGCGCGGTTTCAACCGCGAGGCATGGGCGTTGGCCAACGGTTTGGCCGGTATCGGCAGC
GTGGGCGCGGCGCGGACGGCGGTTGATGCGGAAAAACGGCCGTTTTCAGACGGCCTGGCGGCCGTGAGGACGGCGATCAG
TCTGCGCTGGCAGCGTTGGTACGGGCAGGGCGCGGATAACGGGGTGGCGCTGATGCGGGCGTTGAGTGTGGGCGAGCAGG
GGGCGTTGTCCGACGAAATGTGGCAGGTACTGCGCCCGCTGGGGCTGAATCATTTGGTGAGTATTTCGGGGCTGCATGTA
TCGATGGTGGCTCTGCTGGCCGCCGTATTCGGGCGGGTGCTGCTGAAATATGGGCCGCATACGCCCAAACGGCCGCGTCT
GTGGCTGTTGACTGTCGGTTTGGCGGCAGCATGGGCGTATGCGGCGTTGGCCGGTTTTGCCGTACCGACGGTACGTGCGG
CGGCGATGCTGACGGTGGTGGCGCTGGCATGGGCGCGGGGCGGAACGGCATCGGCGTGGACGGCTTGGTGGGCGGCGTTG
GCGGGGGTGCTGACGCTGTGGCCGACGGCAGTTCTGGCGGCGGGGACATGGTTGTCTTTCGGTTTGGTGGGTGCTTTGCT
GTGGGGCGGCAGTTGGCGCACGGGTGAGCAGGGAGGCGGGCTTTGGCGGGCGCAATGGGCGGCAGGTATGATGTCGGCAG
TGATGTTGGGCTACGGATTTGCGGTGCTGCCGTTATGGAGTCCGGCGGTCAATCTGCCCGCGATACCGTGGTTTTCATGG
GTGTTGGTGCCTTTGGCACTGGCCGCTTCGGCAATACCGTGGCCGCCGCTGCAACAGGCGGCGGTTTGGTTGGGCGAATA
CACTTGGCGCGCACTGGCATGGCTGGCCGAGTATGCGCCCGAGTGGTCGGTAGCTGCCGCGCCTTGGCCGCTGGCTGCGG
CCGCATTTTGTGCCGTGGCGGTATGGCTGGTACCGGCGGGCTTGGGTTTGCGCCCGTGGGCGGCGGCGGTTTTGCTGCTG
TTTGTGCTGTACCGGCCGGAGCGGCCGCCGTCAGGCCGTCTGAATGTAACGGTGCTGGACAGCGGGCAGGGGTTGGCGGT
ATGGCTACAAACGGCCAATCGGGATTTATTGTTCGATACGGGAACGGCCGCCGCTGCCGGCGGTCAGGTCATACCGGCAT
TGCGCGCGGCCGGTGTGCGGCGTTTGGACACGCTGGTATTCTCGCACCGGGATAACGATCACGACGGCGGCGGGCAGATG
GTGCGGCAGGCATTTGCGCCCGATAGAGTGTGGGCGGGGCAGCCGGAGTTTTACAGCGGGGCACGGCACTGTTCGCCTGC
ATCGTGGCAGTGGGACGGTGTCCATTTCGAGTGGCTGACACCGGAGGAGTCGGCCGACAGCGATAACGGGAAGAGCTGTG
TGCTGCGGGCGGTGGCCGGCGGGGAGGCGGTGCTGCTGACCGGCGATTTGGACAGTCGGGGCGAGCAGCGGCTGATAGCG
CAATACGGCTCCGCGCTGTTCAGCCAGCTGCTGATTTTGGGACACCACGGCAGCAACACATCGTCTGCGGGCCGTTTTTT
GAATCTGGTGTCGCCCGAATATGCCGTTGCGTCCAGCGGTTATGCCAATGCCTACGGTCACCCGTCGCCTGCCGTGCAGA
ACCGTGTGCGCGCCCACGGCGGCCGTCTGCTGCGTACCGATTTGTCCGGTGCATGGCGGTTCGAACTGGGGACGGGGCAG
CGTTTGCCCGTCCAAGTGCGGCCGTGGCGGCCGTATTGGCAGAAAAAGCCGTTTGATTGGGTATGA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(23-163)

Metallo-beta-lactamase superfamily (Lactamase_B)

(502-678)

Competence protein (Competence)

(208-464)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

55.87

100

0.559