Detailed information NTG0941264

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: V6K67_RS06920
• Genome accession: NZ_CP145941
• Coordinates: 1324202..1325083 (-)
• Length: 293 a.a.
• NCBI ID: WP_011226089.1
• Uniprot ID: Q5M441
• Organism: Streptococcus thermophilus strain TCI633
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1319202..1330083

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6K67_RS06895 (V6K67_06895)	vicR	1319908..1320615 (-)	708	WP_011227274.1	response regulator YycF	Regulator
V6K67_RS06900 (V6K67_06900)	-	1321141..1321908 (+)	768	WP_011227275.1	amino acid ABC transporter ATP-binding protein	-
V6K67_RS06905 (V6K67_06905)	-	1321920..1322753 (+)	834	WP_011227276.1	transporter substrate-binding domain-containing protein	-
V6K67_RS06910 (V6K67_06910)	-	1322771..1323469 (+)	699	WP_011226087.1	amino acid ABC transporter permease	-
V6K67_RS06915 (V6K67_06915)	-	1323481..1324131 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
V6K67_RS06920 (V6K67_06920)	endA	1324202..1325083 (-)	882	WP_011226089.1	DNA/RNA non-specific endonuclease	Machinery gene
V6K67_RS06925 (V6K67_06925)	-	1325145..1325333 (-)	189	WP_011227277.1	DNA-directed RNA polymerase subunit beta	-
V6K67_RS06930 (V6K67_06930)	murA	1325335..1326606 (-)	1272	WP_041827046.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
V6K67_RS06935 (V6K67_06935)	-	1326676..1326912 (-)	237	WP_002946959.1	DUF1146 family protein	-
V6K67_RS06940 (V6K67_06940)	galE	1327100..1328113 (-)	1014	WP_011227279.1	UDP-glucose 4-epimerase GalE	-
V6K67_RS06945 (V6K67_06945)	-	1328128..1328583 (-)	456	WP_041827047.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31757.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=941264 V6K67_RS06920 WP_011226089.1 1324202..1325083(-) (endA) [Streptococcus thermophilus strain TCI633]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVAGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=941264 V6K67_RS06920 WP_011226089.1 1324202..1325083(-) (endA) [Streptococcus thermophilus strain TCI633]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTGCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCCCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

3D structure

• AlphaFold DB: Q5M441

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594