Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   V6T01_RS01590 Genome accession   NZ_CP145856
Coordinates   293147..294676 (+) Length   509 a.a.
NCBI ID   WP_175062728.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 288147..299676
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T01_RS01565 (V6T01_01560) - 288611..289282 (-) 672 WP_073949300.1 potassium channel family protein -
  V6T01_RS01570 (V6T01_01565) - 289322..290686 (-) 1365 WP_410541227.1 TrkH family potassium uptake protein -
  V6T01_RS01575 (V6T01_01570) rsmG 290755..291468 (-) 714 WP_175062726.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  V6T01_RS01580 (V6T01_01575) - 291768..292304 (+) 537 WP_175062727.1 DUF177 domain-containing protein -
  V6T01_RS01585 (V6T01_01580) covR 292461..293150 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  V6T01_RS01590 (V6T01_01585) covS 293147..294676 (+) 1530 WP_175062728.1 HAMP domain-containing histidine kinase Regulator
  V6T01_RS01595 (V6T01_01590) nrdR 294798..295277 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  V6T01_RS01600 (V6T01_01595) - 295274..296449 (+) 1176 WP_129852167.1 DnaD domain protein -
  V6T01_RS01605 (V6T01_01600) dnaI 296453..297355 (+) 903 WP_002883792.1 primosomal protein DnaI -
  V6T01_RS01610 (V6T01_01605) der 297460..298770 (+) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  V6T01_RS01615 (V6T01_01610) - 298834..299463 (+) 630 WP_410541226.1 HI_0552 family protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58013.40 Da        Isoelectric Point: 5.2781

>NTDB_id=940164 V6T01_RS01590 WP_175062728.1 293147..294676(+) (covS) [Streptococcus salivarius strain KSS1]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNTTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDAMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=940164 V6T01_RS01590 WP_175062728.1 293147..294676(+) (covS) [Streptococcus salivarius strain KSS1]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTGTTTTCTCAGCCAATACGCTACTTTTGCAACGTGAACGTCAAAATGTAA
ACACTACAATCTCAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCCGACGAAGAGTTGAGTCCAGAACCGCTTTTA
GCGGCCCTTTATTCGCCTAAAAATATCTATGCATCGATCATTAATGGAGTGCTTTCTGAAAAGCACTCTTTGGATGGTCA
GGTTGCGATTTCTAATAAATTATATTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAGAACACAGATTCGCCTCCAGGTATGTCCGAAGTAAATAAACTGAAGTCAGTATCCTATAAAGGGAAGCGTGGTTTC
CTGCTGCAAGTTCCAATCTACGGTAAAGATAAAAAGACCATCGTTGGTTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTTAAAGAGCGTTTGATTTTCTTATTGATTTTCCTCGAAGTGGGAATGACGGTCCTAGTTATCGCAGCAACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACACCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGGAAAAATGACCCTGAAATCCTTGAGGAAAGTCTTGAGGCTGCAAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCACAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGTGTCTTGCATGAAGATTACCAATTCTATCTCA
ATGATTTCGAGAGCTCAGAGCGCCCAGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGCAATGTTGGTACAAGTGCA
AGATAATGGTGAAGGGATCTCTAAAGAAGATATTGAGCATATCTTTGAGCGCTTCTACCGTTCAGATAAGGCACGTAATC
GTACAACAACACAATCTGGTGTTGGTATTGGTTTGTCAATTCTTTACCAAATTGTGGAAGCTTATCGTTGCCGTATCGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCGGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(217-269)

ArlS sensor domain (ArlS_N)

(43-191)

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

99.804

100

0.998