Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   V5G19_RS07855 Genome accession   NZ_CP145028
Coordinates   1523966..1524715 (-) Length   249 a.a.
NCBI ID   WP_306307845.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO_R_2024     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1518966..1529715
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G19_RS07835 (V5G19_07840) - 1519511..1520739 (-) 1229 Protein_1526 multidrug effflux MFS transporter -
  V5G19_RS07840 (V5G19_07845) - 1520855..1521730 (-) 876 WP_003689397.1 DMT family transporter -
  V5G19_RS07845 (V5G19_07850) - 1521913..1522326 (+) 414 Protein_1528 pilin -
  V5G19_RS07850 (V5G19_07855) - 1522872..1523696 (+) 825 WP_127514817.1 opacity family porin -
  V5G19_RS07855 (V5G19_07860) pilA 1523966..1524715 (-) 750 WP_306307845.1 nitrilase-related carbon-nitrogen hydrolase Machinery gene
  V5G19_RS07860 (V5G19_07865) - 1524698..1525570 (+) 873 WP_003693577.1 prephenate dehydrogenase -
  V5G19_RS07865 (V5G19_07870) - 1525628..1526782 (-) 1155 WP_010358927.1 NnrS family protein -
  V5G19_RS07870 (V5G19_07875) - 1526827..1527195 (-) 369 WP_003689404.1 hemerythrin domain-containing protein -
  V5G19_RS07875 (V5G19_07880) - 1527369..1527812 (+) 444 WP_003689406.1 Rrf2 family transcriptional regulator -
  V5G19_RS07880 (V5G19_07885) - 1527822..1527950 (+) 129 WP_010358932.1 hypothetical protein -
  V5G19_RS07885 (V5G19_07890) - 1527974..1528594 (-) 621 WP_010358934.1 L-threonylcarbamoyladenylate synthase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 26574.78 Da        Isoelectric Point: 6.7235

>NTDB_id=936130 V5G19_RS07855 WP_306307845.1 1523966..1524715(-) (pilA) [Neisseria gonorrhoeae strain WHO_R_2024]
MVQNGHLCKRFSQSAAMVAYRRNMPQGRQEKGEEMDKIRVAAVQMVSGVSPETNVAAMKRLVARAAEQGADWVLLPEYWV
LMGANDTGKLALAEPLGGGRFQTALSETAKECGVVLFGGTVPLQSPEARGIDIVLADTAGRLPTQLHLMEEIKKVKRVLQ
KAIPGAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGIDDLRPFDA
RAFVDALLD

Nucleotide


Download         Length: 750 bp        

>NTDB_id=936130 V5G19_RS07855 WP_306307845.1 1523966..1524715(-) (pilA) [Neisseria gonorrhoeae strain WHO_R_2024]
ATGGTTCAAAATGGGCATTTGTGTAAACGGTTTTCGCAAAGTGCCGCCATGGTAGCCTATCGGCGGAATATGCCGCAAGG
TCGGCAGGAAAAAGGAGAAGAAATGGACAAAATCAGAGTTGCCGCCGTGCAGATGGTGTCGGGCGTGTCGCCGGAAACCA
ACGTCGCCGCCATGAAACGCCTGGTCGCACGGGCGGCGGAGCAGGGTGCGGATTGGGTGCTGCTGCCCGAATATTGGGTG
CTGATGGGCGCAAACGATACCGGCAAACTCGCACTTGCCGAGCCTTTGGGCGGCGGACGCTTTCAGACGGCATTGAGCGA
AACGGCGAAAGAATGCGGCGTGGTGCTGTTCGGCGGAACCGTGCCGCTGCAAAGCCCCGAAGCGCGCGGGATCGACATCG
TGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTGATGGAAGAAATCAAAAAAGTGAAGCGCGTGCTGCAA
AAAGCCATTCCCGGCGCGCCGCACGAAATCATCGTCGTACTCGATGCCAATATCGGGCAAAACGCCGTCAACCAAGTCAA
AGCCTTTGACGACGCATTGGGGCTGACGGGGCTTATCGTTACCAAACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCG
CGCTTGCTTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTGGGCGAAGGCATAGACGACCTGCGCCCGTTTGACGCG
CGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(124-248)

Carbon-nitrogen hydrolase (CN_hydrolase)

(39-149)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

79.769

69.478

0.554