Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   ACD269_RS09835 Genome accession   NZ_CP168260
Coordinates   1898338..1899291 (-) Length   317 a.a.
NCBI ID   WP_000345132.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain FC2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1893338..1904291
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD269_RS09805 (ACD269_09805) - 1894099..1894722 (-) 624 WP_050210601.1 hypothetical protein -
  ACD269_RS09810 (ACD269_09810) jag 1894773..1895759 (-) 987 WP_000260024.1 RNA-binding cell elongation regulator Jag/EloR -
  ACD269_RS09815 (ACD269_09815) - 1895778..1896602 (-) 825 WP_000727911.1 membrane protein insertase YidC -
  ACD269_RS09820 (ACD269_09820) rnpA 1896577..1896948 (-) 372 WP_000739246.1 ribonuclease P protein component -
  ACD269_RS09825 (ACD269_09825) - 1896965..1897096 (-) 132 WP_000768904.1 hypothetical protein -
  ACD269_RS09830 (ACD269_09830) - 1897097..1898287 (-) 1191 WP_000167770.1 acetate kinase -
  ACD269_RS09835 (ACD269_09835) comGH 1898338..1899291 (-) 954 WP_000345132.1 class I SAM-dependent methyltransferase Machinery gene
  ACD269_RS09840 (ACD269_09840) - 1899637..1900439 (+) 803 Protein_1913 IS5 family transposase -
  ACD269_RS09845 (ACD269_09845) - 1900590..1901066 (+) 477 WP_000777686.1 GNAT family N-acetyltransferase -
  ACD269_RS09850 (ACD269_09850) comGG/cglG 1901721..1902134 (-) 414 WP_000265615.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACD269_RS09855 (ACD269_09855) comGF/cglF 1902112..1902573 (-) 462 WP_000250520.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACD269_RS09860 (ACD269_09860) comGE/cglE 1902536..1902838 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACD269_RS09865 (ACD269_09865) comGD/cglD 1902801..1903235 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACD269_RS09870 (ACD269_09870) comGC/cglC 1903198..1903521 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35661.78 Da        Isoelectric Point: 4.1925

>NTDB_id=935272 ACD269_RS09835 WP_000345132.1 1898338..1899291(-) (comGH) [Streptococcus pneumoniae strain FC2]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFTEEEITILEMGSGMGILGATFLTSLAKKVDYLGMEMDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANANQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=935272 ACD269_RS09835 WP_000345132.1 1898338..1899291(-) (comGH) [Streptococcus pneumoniae strain FC2]
ATGGATTTTGAAAAAATTGAACAAGCCTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGACAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACGCCAGATGCTATTGCCTTACTTTTGGTATTTATTGTGGAAGAGTTGTTTAC
AGAGGAGGAAATCACTATCCTTGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTAACCTCGCTTGCTAAAA
AAGTGGATTACTTGGGAATGGAAATGGATGATTTGCTGATTGATTTGGCAGCTAGTATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAACCAATCTAAGACTATTTTTATCCTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA140

54.313

98.738

0.536
  comGH Streptococcus mutans UA159

53.994

98.738

0.533