Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   MWM14_RS12665 Genome accession   NZ_AP025621
Coordinates   2521912..2523159 (-) Length   415 a.a.
NCBI ID   WP_003251603.1    Uniprot ID   -
Organism   Parageobacillus thermoglucosidasius strain BH4-1     
Function   unknown (predicted from homology)   
Unclear

Genomic Context

Location: 2516912..2528159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MWM14_RS12645 (PthBH41_24700) spoVS 2517388..2517648 (-) 261 WP_003251598.1 stage V sporulation protein SpoVS -
  MWM14_RS12650 (PthBH41_24710) - 2517775..2518569 (-) 795 WP_003251599.1 TIGR00282 family metallophosphoesterase -
  MWM14_RS12655 (PthBH41_24720) rny 2518653..2520218 (-) 1566 WP_003251600.1 ribonuclease Y -
  MWM14_RS12660 (PthBH41_24730) recA 2520697..2521749 (-) 1053 WP_003251602.1 recombinase RecA Machinery gene
  MWM14_RS12665 (PthBH41_24740) cinA 2521912..2523159 (-) 1248 WP_003251603.1 competence/damage-inducible protein A Machinery gene
  MWM14_RS12670 (PthBH41_24750) pgsA 2523256..2523834 (-) 579 WP_003251605.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MWM14_RS12675 (PthBH41_24760) - 2523890..2524774 (-) 885 WP_003251607.1 helix-turn-helix domain-containing protein -
  MWM14_RS12680 (PthBH41_24770) - 2524799..2525590 (-) 792 WP_003251609.1 DUF3388 domain-containing protein -
  MWM14_RS12685 (PthBH41_24780) - 2525731..2525979 (-) 249 WP_003251611.1 DUF3243 domain-containing protein -
  MWM14_RS12690 (PthBH41_24790) - 2526042..2526758 (-) 717 WP_003251613.1 SDR family oxidoreductase -
  MWM14_RS12695 (PthBH41_24800) - 2526798..2528090 (-) 1293 WP_003251616.1 pitrilysin family protein -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 44968.85 Da        Isoelectric Point: 7.1401

>NTDB_id=93103 MWM14_RS12665 WP_003251603.1 2521912..2523159(-) (cinA) [Parageobacillus thermoglucosidasius strain BH4-1]
MNAEIIAVGSELLLGQIANTNAQFLSAQLAELGINVYFHTVVGDNADRLEKAVKVAQTRANLIIFTGGLGPTKDDLTKET
IARLLQRELVIDKEALHSIEAYFARTGRTMTENNKKQALVLQGSTVFRNEHGMAPGMAMTVGAITYMLLPGPPKEMQPMF
SKYGRPFLMEKLDRHERIESRVLRFFGIGESQLETEIEDLIEQQSNPTIAPLAGDGEVTLRLTAKHHSEIEAKKLLDQTE
QAILTRVGRYFYGYNDDTLFKNTVKLLKEKKKTVAAAESLTGGLFLTELTAIPGASQVVRGGVVCYTNEVKEKVLHVPAS
VLATDGAVSERCAKLLAENVRALCGADIGISFTGVAGPDPLEGKPVGTVYIGISTSENETAVHALALSGPRDAIRTRTAK
YGCSIILKKLAAACL

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=93103 MWM14_RS12665 WP_003251603.1 2521912..2523159(-) (cinA) [Parageobacillus thermoglucosidasius strain BH4-1]
TTGAATGCGGAAATTATCGCTGTCGGCTCCGAATTATTGCTTGGGCAGATCGCTAACACGAATGCGCAGTTTTTATCTGC
CCAGCTCGCTGAACTTGGCATTAACGTCTATTTTCACACTGTTGTTGGCGACAATGCCGACCGTTTGGAAAAAGCGGTAA
AAGTGGCACAAACACGAGCGAATTTAATTATTTTCACAGGCGGACTTGGTCCGACGAAAGACGATTTGACAAAAGAGACG
ATCGCCCGCCTATTGCAACGGGAACTTGTCATTGACAAGGAGGCGCTTCATTCCATTGAAGCGTATTTTGCCCGCACAGG
CCGAACAATGACAGAAAACAATAAAAAACAGGCGCTTGTCTTGCAAGGCTCGACTGTGTTCAGAAACGAACATGGAATGG
CGCCAGGAATGGCAATGACGGTCGGTGCGATTACGTATATGCTTCTCCCAGGTCCCCCAAAGGAAATGCAGCCAATGTTC
AGCAAATACGGGCGCCCGTTCTTAATGGAGAAGCTGGATCGCCATGAGCGCATCGAATCGCGTGTGCTACGCTTTTTCGG
CATCGGTGAATCGCAGCTTGAGACAGAAATCGAAGATCTTATTGAGCAACAATCAAACCCGACGATCGCCCCTCTTGCCG
GCGATGGGGAAGTAACGTTGCGTTTGACTGCAAAACACCATTCGGAAATCGAAGCCAAAAAGCTGCTTGACCAGACCGAA
CAAGCGATTTTAACGCGCGTCGGCCGTTATTTTTACGGCTACAATGACGACACGTTGTTTAAAAATACGGTGAAGCTGTT
GAAGGAAAAAAAGAAAACGGTCGCGGCTGCCGAAAGCCTCACTGGCGGGCTTTTCTTAACGGAATTAACGGCCATTCCCG
GCGCTTCCCAAGTGGTTCGCGGCGGGGTCGTCTGCTATACCAATGAAGTGAAGGAGAAAGTGCTTCACGTTCCCGCTTCT
GTTTTAGCAACCGACGGAGCGGTAAGTGAACGCTGCGCGAAGCTGTTGGCGGAAAATGTCCGCGCGCTTTGCGGCGCAGA
TATTGGCATTAGCTTTACAGGCGTGGCAGGACCGGATCCGCTTGAAGGAAAGCCGGTCGGTACCGTATATATTGGCATTT
CCACTTCTGAAAATGAAACAGCTGTCCACGCCCTCGCGTTATCCGGCCCGCGTGATGCAATCCGCACTCGCACTGCTAAA
TACGGCTGCTCCATTATATTAAAAAAATTGGCAGCTGCATGTTTGTAG

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

60.294

98.313

0.593
  cinA Streptococcus mitis SK321

46.667

100

0.472
  cinA Streptococcus mutans UA159

48.872

96.145

0.47
  cinA Streptococcus mitis NCTC 12261

46.19

100

0.467
  cinA Streptococcus pneumoniae TIGR4

45.346

100

0.458
  cinA Streptococcus pneumoniae Rx1

45.346

100

0.458
  cinA Streptococcus pneumoniae R6

45.346

100

0.458
  cinA Streptococcus pneumoniae D39

45.107

100

0.455
  cinA Streptococcus suis isolate S10

42.744

91.325

0.39

Multiple sequence alignment