Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   ACB340_RS07740 Genome accession   NZ_CP167005
Coordinates   1517481..1518263 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain Isolate 27     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1512481..1523263
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB340_RS07715 (ACB340_07715) gatB 1512562..1514001 (-) 1440 WP_023078673.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  ACB340_RS07720 (ACB340_07720) gatA 1514001..1515467 (-) 1467 WP_023078692.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  ACB340_RS07725 (ACB340_07725) gatC 1515467..1515769 (-) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  ACB340_RS07730 (ACB340_07730) - 1516001..1516321 (-) 321 Protein_1469 putative PEP-binding protein -
  ACB340_RS07735 (ACB340_07735) - 1516780..1517334 (-) 555 WP_002992568.1 cysteine hydrolase family protein -
  ACB340_RS07740 (ACB340_07740) codY 1517481..1518263 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  ACB340_RS07745 (ACB340_07745) - 1518480..1519694 (-) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  ACB340_RS07750 (ACB340_07750) - 1519925..1520377 (+) 453 WP_002983265.1 universal stress protein -
  ACB340_RS07755 (ACB340_07755) - 1520500..1521888 (-) 1389 WP_002992572.1 Cof-type HAD-IIB family hydrolase -
  ACB340_RS07760 (ACB340_07760) - 1521960..1522925 (+) 966 WP_023078713.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=930094 ACB340_RS07740 WP_002983278.1 1517481..1518263(-) (codY) [Streptococcus pyogenes strain Isolate 27]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=930094 ACB340_RS07740 WP_002983278.1 1517481..1518263(-) (codY) [Streptococcus pyogenes strain Isolate 27]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACATTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAGTTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAATTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAATTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504