Detailed information NTG0929993

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: ACB354_RS07065
• Genome accession: NZ_CP167004
• Coordinates: 1330654..1331520 (-)
• Length: 288 a.a.
• NCBI ID: WP_011184363.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 28
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1325654..1336520

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB354_RS07045 (ACB354_07050)	-	1325845..1326231 (-)	387	WP_002990406.1	YbgA family protein	-
ACB354_RS07050 (ACB354_07055)	-	1326224..1326601 (-)	378	WP_021340346.1	OsmC family protein	-
ACB354_RS07055 (ACB354_07060)	pheT	1326713..1329118 (-)	2406	WP_023078221.1	phenylalanine--tRNA ligase subunit beta	-
ACB354_RS07060 (ACB354_07065)	pheS	1329328..1330371 (-)	1044	WP_003057440.1	phenylalanine--tRNA ligase subunit alpha	-
ACB354_RS07065 (ACB354_07070)	endA	1330654..1331520 (-)	867	WP_011184363.1	DNA/RNA non-specific endonuclease	Machinery gene
ACB354_RS07070 (ACB354_07075)	-	1331556..1331744 (-)	189	WP_011017613.1	DNA-directed RNA polymerase subunit beta	-
ACB354_RS07075 (ACB354_07080)	murA	1331748..1333019 (-)	1272	WP_002994428.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ACB354_RS07080 (ACB354_07085)	-	1333084..1333320 (-)	237	WP_280529076.1	DUF1146 family protein	-
ACB354_RS07085 (ACB354_07090)	-	1333607..1334023 (-)	417	WP_002985233.1	F0F1 ATP synthase subunit epsilon	-
ACB354_RS07090 (ACB354_07095)	atpD	1334036..1335442 (-)	1407	WP_011017611.1	F0F1 ATP synthase subunit beta	-
ACB354_RS07095 (ACB354_07100)	-	1335604..1336479 (-)	876	WP_002985236.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 288 a.a.
• Molecular weight: 32111.62 Da
• Isoelectric Point: 10.4010

>NTDB_id=929993 ACB354_RS07065 WP_011184363.1 1330654..1331520(-) (endA) [Streptococcus pyogenes strain Isolate 28]
MLAKKKRKRVLNSFLLILLVLGSNCLAKSDFIASNHPIKQLYQTLVGEKKKSLLTHNNLPADVPTEALAASVLTPSIKKQ
LGPDVQWNGAGAYIINRNKTDLNAKVASLPYANNETKWVQEQKVPKRANALLTKSTRQYRNRYQTDNAYRNFKPAGWHRL
HRLKGSYDHAVDRGHLLGYALVGGLKGLDASTGNPDNIATQLSWANQANKPYSTGQNYYEGLVCRALDKGHRVRYRVTLL
YDGDNLLASGSHLEAKSSDDSLTFNVFVPNVQPGLTVDYRTRQIAINL

Nucleotide

• Length: 867 bp

>NTDB_id=929993 ACB354_RS07065 WP_011184363.1 1330654..1331520(-) (endA) [Streptococcus pyogenes strain Isolate 28]
ATGTTAGCAAAGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAACTGCCTTGC
TAAGAGTGATTTCATAGCTAGCAATCACCCTATCAAGCAACTTTATCAGACTCTTGTTGGGGAGAAGAAAAAATCATTAC
TCACACATAATAATTTGCCCGCTGATGTTCCCACAGAAGCTCTGGCGGCATCGGTATTAACACCATCAATCAAAAAGCAA
CTAGGTCCAGATGTTCAGTGGAATGGAGCAGGCGCCTATATTATCAACAGGAACAAAACAGATTTAAATGCTAAGGTAGC
CAGTCTGCCCTATGCCAACAATGAAACCAAATGGGTGCAAGAGCAAAAGGTTCCTAAAAGAGCTAATGCCTTACTTACTA
AGTCGACACGACAGTATCGAAATCGCTATCAAACGGACAATGCTTATCGTAACTTTAAGCCAGCAGGTTGGCACCGATTG
CACCGCTTAAAAGGAAGTTATGATCACGCGGTTGATAGAGGGCATTTGCTAGGTTATGCTTTAGTTGGTGGACTGAAAGG
TTTAGATGCTTCTACCGGTAATCCTGATAATATTGCCACTCAACTAAGTTGGGCTAATCAAGCAAATAAACCCTACTCGA
CAGGTCAGAATTACTATGAAGGTTTAGTATGTCGTGCTTTGGATAAGGGGCATCGCGTCCGCTACCGTGTCACCCTACTT
TATGATGGTGATAATCTACTAGCCAGCGGTAGCCATTTGGAGGCTAAATCCTCTGATGACAGCTTGACTTTTAACGTGTT
TGTTCCAAATGTCCAACCAGGATTGACCGTTGACTATAGGACGAGACAAATAGCTATCAATCTCTAA

Domains

Predicted by InterProScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (111-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	57.806	82.292	0.476
endA	Streptococcus pneumoniae D39	57.806	82.292	0.476
endA	Streptococcus pneumoniae R6	57.806	82.292	0.476
endA	Streptococcus pneumoniae TIGR4	57.806	82.292	0.476