Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   ACA109_RS06540 Genome accession   NZ_CP166872
Coordinates   1290232..1291005 (-) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain 24EBSta0529     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1285232..1296005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACA109_RS06505 (ACA109_06505) - 1285485..1286255 (-) 771 WP_371257290.1 isoprenyl transferase -
  ACA109_RS06510 (ACA109_06510) frr 1286628..1287182 (-) 555 WP_001280006.1 ribosome recycling factor -
  ACA109_RS06515 (ACA109_06515) pyrH 1287201..1287923 (-) 723 WP_000057330.1 UMP kinase -
  ACA109_RS06520 (ACA109_06520) tsf 1288060..1288941 (-) 882 WP_000201387.1 translation elongation factor Ts -
  ACA109_RS06525 (ACA109_06525) - 1288976..1289089 (-) 114 WP_001789890.1 hypothetical protein -
  ACA109_RS06530 (ACA109_06530) rpsB 1289123..1289890 (-) 768 WP_000268484.1 30S ribosomal protein S2 -
  ACA109_RS06535 (ACA109_06535) - 1290089..1290181 (-) 93 WP_031788481.1 hypothetical protein -
  ACA109_RS06540 (ACA109_06540) codY 1290232..1291005 (-) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  ACA109_RS06545 (ACA109_06545) hslU 1291030..1292433 (-) 1404 WP_371257328.1 ATP-dependent protease ATPase subunit HslU -
  ACA109_RS06550 (ACA109_06550) hslV 1292499..1293044 (-) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  ACA109_RS06555 (ACA109_06555) xerC 1293041..1293937 (-) 897 WP_001015609.1 tyrosine recombinase XerC -
  ACA109_RS06560 (ACA109_06560) trmFO 1294355..1295662 (-) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=929212 ACA109_RS06540 WP_000055337.1 1290232..1291005(-) (codY) [Staphylococcus aureus strain 24EBSta0529]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=929212 ACA109_RS06540 WP_000055337.1 1290232..1291005(-) (codY) [Staphylococcus aureus strain 24EBSta0529]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCGATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428