Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   VF946_RS08245 Genome accession   NZ_CP141824
Coordinates   1608461..1609810 (-) Length   449 a.a.
NCBI ID   WP_024405653.1    Uniprot ID   -
Organism   Streptococcus suis strain HB18     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1603461..1614810
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VF946_RS08225 recR 1604137..1604733 (-) 597 WP_002935848.1 recombination mediator RecR -
  VF946_RS08230 pbp2b 1604742..1606817 (-) 2076 WP_238716781.1 penicillin-binding protein PBP2B -
  VF946_RS08235 - 1606909..1607283 (-) 375 WP_023369696.1 ATP-binding cassette domain-containing protein -
  VF946_RS08240 vicX 1607651..1608454 (-) 804 WP_023369694.1 MBL fold metallo-hydrolase Regulator
  VF946_RS08245 micB 1608461..1609810 (-) 1350 WP_024405653.1 cell wall metabolism sensor histidine kinase VicK Regulator
  VF946_RS08250 micA 1609803..1610507 (-) 705 WP_002935840.1 response regulator YycF Regulator
  VF946_RS08255 - 1610701..1611462 (+) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  VF946_RS08260 - 1611473..1612312 (+) 840 WP_023369690.1 transporter substrate-binding domain-containing protein -
  VF946_RS08265 - 1612327..1613025 (+) 699 WP_015646621.1 amino acid ABC transporter permease -
  VF946_RS08270 - 1613040..1613699 (+) 660 WP_002935828.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51077.16 Da        Isoelectric Point: 4.4860

>NTDB_id=919765 VF946_RS08245 WP_024405653.1 1608461..1609810(-) (micB) [Streptococcus suis strain HB18]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHINENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGYGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=919765 VF946_RS08245 WP_024405653.1 1608461..1609810(-) (micB) [Streptococcus suis strain HB18]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAGCAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGATATGGCGAATTCTCTTAATGATCTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACGTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAGTATCACCTGCTCGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGCTGGCTCAGACACCTGAG
ATTGTGATTGATCACATCAATGAAAATGAAGAATTTCTGACTTTACGTGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCCTGGTAGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTATTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTTAG
CTTATCGCGCATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCAGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTTATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635