Detailed information NTG0914772

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: SC851_RS08350
• Genome accession: NZ_CP140606
• Coordinates: 1678748..1679584 (-)
• Length: 278 a.a.
• NCBI ID: WP_004049325.1
• Uniprot ID: A0A4V1PRC4
• Organism: Ligilactobacillus murinus strain XYW20210915003
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1673748..1684584

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SC851_RS08320 (SC851_08285)	-	1673889..1674494 (-)	606	WP_004049315.1	response regulator transcription factor	-
SC851_RS08325 (SC851_08290)	-	1674472..1675608 (-)	1137	WP_004049316.1	sensor histidine kinase	-
SC851_RS08330 (SC851_08295)	-	1675610..1676329 (-)	720	WP_004049317.1	ABC transporter permease	-
SC851_RS08335 (SC851_08300)	-	1676313..1677203 (-)	891	WP_405257343.1	ABC transporter ATP-binding protein	-
SC851_RS08340 (SC851_08305)	-	1677335..1678210 (-)	876	WP_004049321.1	CPBP family intramembrane glutamic endopeptidase	-
SC851_RS08345 (SC851_08310)	-	1678437..1678748 (-)	312	WP_004049323.1	hypothetical protein	-
SC851_RS08350 (SC851_08315)	endA	1678748..1679584 (-)	837	WP_004049325.1	DNA/RNA non-specific endonuclease	Machinery gene
SC851_RS08355 (SC851_08320)	asnA	1679644..1680651 (-)	1008	WP_004049328.1	aspartate--ammonia ligase	-
SC851_RS08360 (SC851_08325)	-	1680832..1681479 (+)	648	WP_004049330.1	nitroreductase	-
SC851_RS08365 (SC851_08330)	-	1681648..1682073 (-)	426	WP_004049332.1	N-acetyltransferase	-
SC851_RS08370 (SC851_08335)	-	1682141..1682527 (+)	387	WP_004049334.1	iron chaperone	-
SC851_RS08375 (SC851_08340)	-	1683299..1683565 (-)	267	WP_004049336.1	hypothetical protein	-
SC851_RS08380 (SC851_08345)	-	1683893..1684072 (-)	180	WP_039936126.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30334.02 Da
• Isoelectric Point: 10.5647

>NTDB_id=914772 SC851_RS08350 WP_004049325.1 1678748..1679584(-) (endA) [Ligilactobacillus murinus strain XYW20210915003]
MKFKKILTGFVAALMLSGAIGAPVTAKATTHYGGWRTHQKNSSSGSGELKKSTPSQQLAQTVLTPDVVKQLGGEQNLKWN
NSGAFIVNNNKTGLKAKVSSAPYATNEVDSLKRPTVANALLNRTTRQYKNRHQTNNGSTKWKPQGFKQLTNLSGAYNHAY
DRGHLLGYALVGNIRGFDASESNPKNIATQTAWANEANAKYSTGQNYYESLVRKALDRNKTVRYRVTNVYSGNNLVPSGA
HLEAKASDGSLEYNVFIPNVQKGLKIDYATGHAIKENN

Nucleotide

• Length: 837 bp

>NTDB_id=914772 SC851_RS08350 WP_004049325.1 1678748..1679584(-) (endA) [Ligilactobacillus murinus strain XYW20210915003]
ATGAAGTTCAAAAAAATATTGACCGGATTTGTGGCAGCTTTGATGCTCAGTGGTGCGATCGGGGCACCGGTAACAGCTAA
AGCAACGACGCACTATGGTGGTTGGCGCACACATCAAAAAAATAGTTCGAGTGGCTCTGGTGAATTAAAAAAGAGCACTC
CATCACAACAATTAGCCCAAACGGTTTTGACGCCGGATGTTGTTAAACAATTAGGCGGTGAGCAAAATCTCAAATGGAAC
AACAGTGGGGCTTTTATCGTTAATAACAACAAGACAGGTTTAAAAGCTAAGGTTTCTAGTGCTCCTTATGCAACAAATGA
AGTCGATAGCTTAAAACGTCCGACGGTAGCTAATGCCCTTTTGAATAGGACAACACGGCAATACAAGAATCGCCACCAAA
CTAATAATGGTTCGACTAAATGGAAACCACAGGGCTTTAAGCAACTCACTAACTTAAGTGGCGCCTACAACCATGCTTAT
GATCGCGGACACTTACTAGGGTATGCTTTAGTGGGAAATATTCGTGGTTTTGATGCTAGTGAGAGCAATCCCAAAAATAT
TGCGACTCAGACAGCTTGGGCTAATGAAGCTAATGCAAAATATTCAACAGGTCAAAACTATTACGAAAGTCTTGTTCGAA
AAGCCTTAGATCGTAATAAGACTGTCCGTTATCGTGTGACAAATGTCTATAGCGGTAATAATTTAGTACCATCAGGCGCT
CATTTAGAAGCTAAAGCAAGTGATGGTTCGTTAGAGTATAATGTTTTTATCCCTAATGTTCAAAAGGGATTAAAGATCGA
CTATGCTACTGGTCATGCGATAAAGGAGAACAACTGA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (82-250)

3D structure

• AlphaFold DB: A0A4V1PRC4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	65.471	80.216	0.525
endA	Streptococcus pneumoniae D39	65.471	80.216	0.525
endA	Streptococcus pneumoniae R6	65.471	80.216	0.525
endA	Streptococcus pneumoniae TIGR4	65.471	80.216	0.525