Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | U2W41_RS00680 | Genome accession | NZ_CP140113 |
| Coordinates | 105792..106745 (+) | Length | 317 a.a. |
| NCBI ID | WP_010921802.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain NV28 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 100792..111745
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| U2W41_RS00640 (U2W41_00640) | - | 101619..101984 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| U2W41_RS00645 (U2W41_00645) | comYA | 102077..103015 (+) | 939 | WP_010921798.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| U2W41_RS00650 (U2W41_00650) | comYB | 102951..103985 (+) | 1035 | WP_011054115.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| U2W41_RS00655 (U2W41_00655) | comYC | 103987..104313 (+) | 327 | WP_002986552.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| U2W41_RS00660 (U2W41_00660) | comGD | 104288..104716 (+) | 429 | WP_002986548.1 | competence type IV pilus minor pilin ComGD | - |
| U2W41_RS00665 (U2W41_00665) | comGE | 104673..104957 (+) | 285 | WP_002987779.1 | competence type IV pilus minor pilin ComGE | - |
| U2W41_RS00670 (U2W41_00670) | comYF | 104950..105384 (+) | 435 | WP_010921800.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| U2W41_RS00675 (U2W41_00675) | comGG | 105368..105694 (+) | 327 | WP_010921801.1 | competence type IV pilus minor pilin ComGG | - |
| U2W41_RS00680 (U2W41_00680) | comYH | 105792..106745 (+) | 954 | WP_010921802.1 | class I SAM-dependent methyltransferase | Machinery gene |
| U2W41_RS00685 (U2W41_00685) | - | 106804..108000 (+) | 1197 | WP_010921803.1 | acetate kinase | - |
| U2W41_RS00690 (U2W41_00690) | - | 108187..108495 (+) | 309 | WP_010921804.1 | hypothetical protein | - |
| U2W41_RS00695 (U2W41_00695) | proC | 108578..109348 (-) | 771 | WP_010921805.1 | pyrroline-5-carboxylate reductase | - |
| U2W41_RS00700 (U2W41_00700) | pepA | 109396..110463 (-) | 1068 | WP_010921806.1 | glutamyl aminopeptidase | - |
| U2W41_RS00705 (U2W41_00705) | - | 110928..111212 (+) | 285 | WP_002992749.1 | DUF4651 domain-containing protein | - |
| U2W41_RS00710 (U2W41_00710) | - | 111209..111526 (+) | 318 | WP_011285355.1 | thioredoxin family protein | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 36015.10 Da Isoelectric Point: 4.7205
>NTDB_id=912644 U2W41_RS00680 WP_010921802.1 105792..106745(+) (comYH) [Streptococcus pyogenes strain NV28]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
Nucleotide
Download Length: 954 bp
>NTDB_id=912644 U2W41_RS00680 WP_010921802.1 105792..106745(+) (comYH) [Streptococcus pyogenes strain NV28]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTGTTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTGTTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
65.823 |
99.685 |
0.656 |
| comYH | Streptococcus mutans UA140 |
65.506 |
99.685 |
0.653 |