Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   U0N78_RS04405 Genome accession   NZ_CP140109
Coordinates   911586..912425 (+) Length   279 a.a.
NCBI ID   WP_172045685.1    Uniprot ID   A0A7T1LBM2
Organism   Streptococcus suis strain 2022WUSS148     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 906586..917425
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0N78_RS04375 (U0N78_04375) - 907051..907929 (+) 879 WP_172045688.1 F0F1 ATP synthase subunit gamma -
  U0N78_RS04380 (U0N78_04380) atpD 907949..909355 (+) 1407 WP_002936008.1 F0F1 ATP synthase subunit beta -
  U0N78_RS04385 (U0N78_04385) - 909365..909781 (+) 417 WP_002936007.1 F0F1 ATP synthase subunit epsilon -
  U0N78_RS04390 (U0N78_04390) - 909841..910065 (+) 225 WP_012775178.1 DUF1146 family protein -
  U0N78_RS04395 (U0N78_04395) murA 910089..911372 (+) 1284 WP_172045686.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  U0N78_RS04400 (U0N78_04400) - 911365..911556 (+) 192 WP_002936005.1 DNA-directed RNA polymerase subunit beta -
  U0N78_RS04405 (U0N78_04405) endA 911586..912425 (+) 840 WP_172045685.1 DNA/RNA non-specific endonuclease Machinery gene
  U0N78_RS04410 (U0N78_04410) - 912612..914162 (+) 1551 WP_197315146.1 MFS transporter -
  U0N78_RS04415 (U0N78_04415) - 914225..915253 (+) 1029 WP_125177102.1 sugar kinase -
  U0N78_RS04420 (U0N78_04420) uidA 915269..917068 (+) 1800 WP_197315147.1 beta-glucuronidase -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30104.41 Da        Isoelectric Point: 7.5077

>NTDB_id=912584 U0N78_RS04405 WP_172045685.1 911586..912425(+) (endA) [Streptococcus suis strain 2022WUSS148]
MAKKNVKKQAMSLLSLLATIVVVAGGYLLSDNKSSNVANYSYYVNQSKASESTPSQELASSVLTEDVKKQLGHSIDWNGA
GAFIINGNKTDLDASVSSKPYADNKTKTVQGETVPTVANALLAKSTRQYKSREETGNGSTSWTPPGWHQVQDLDGSYDHA
IDRGHLLGYALIGGLKGFDASTSNPKNIAVQTAWSNQARAEDSTGQNYFESQVRKALDKNKRVRYRVTLVYADEADLVPV
GSHLEAKAADGSLEFNVFVPNVQSGLSINYHSGEIAVNQ

Nucleotide


Download         Length: 840 bp        

>NTDB_id=912584 U0N78_RS04405 WP_172045685.1 911586..912425(+) (endA) [Streptococcus suis strain 2022WUSS148]
ATGGCGAAGAAAAATGTAAAAAAACAAGCAATGAGTCTGCTCAGCTTATTGGCTACGATTGTTGTAGTAGCGGGGGGCTA
TCTTTTAAGTGACAACAAGAGCAGTAACGTTGCTAATTATTCCTATTATGTCAATCAGTCTAAGGCAAGCGAGAGCACAC
CTAGTCAGGAACTAGCTAGTTCTGTATTGACTGAGGATGTAAAGAAACAGCTTGGACATTCAATTGACTGGAATGGAGCG
GGTGCCTTTATCATCAACGGAAATAAGACTGATTTAGATGCGTCAGTCTCTAGTAAACCCTATGCGGATAATAAGACAAA
GACTGTGCAGGGAGAAACGGTTCCAACAGTGGCAAATGCCCTTTTAGCCAAATCAACGCGACAGTATAAGAGTCGTGAAG
AAACAGGAAATGGTTCGACTTCATGGACTCCGCCTGGCTGGCATCAGGTACAGGATTTGGATGGCTCCTATGATCATGCG
ATTGATAGGGGGCATCTGCTGGGCTATGCCTTGATTGGCGGTTTAAAAGGCTTTGATGCTTCAACCAGCAATCCTAAGAA
TATTGCAGTTCAAACAGCTTGGTCCAATCAGGCAAGGGCTGAGGATTCGACGGGGCAAAACTATTTTGAGAGTCAAGTTC
GTAAAGCTTTGGATAAGAACAAACGTGTTCGTTACCGCGTGACCTTGGTGTATGCTGATGAGGCTGATTTGGTTCCAGTC
GGAAGCCATCTAGAGGCAAAAGCAGCAGATGGTAGCCTAGAGTTCAATGTGTTCGTTCCAAATGTGCAGAGCGGTCTCAG
TATCAACTATCATAGTGGGGAAATTGCAGTAAATCAATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T1LBM2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

74.153

84.588

0.627
  endA Streptococcus pneumoniae D39

74.153

84.588

0.627
  endA Streptococcus pneumoniae R6

74.153

84.588

0.627
  endA Streptococcus pneumoniae TIGR4

74.153

84.588

0.627