Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   L6411_RS03525 Genome accession   NZ_AP025333
Coordinates   724690..725532 (+) Length   280 a.a.
NCBI ID   WP_272877493.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-189     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 719690..730532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6411_RS03495 (GUT189_06440) - 719898..720776 (+) 879 WP_024532405.1 F0F1 ATP synthase subunit gamma -
  L6411_RS03500 (GUT189_06450) atpD 720948..722354 (+) 1407 WP_024532406.1 F0F1 ATP synthase subunit beta -
  L6411_RS03505 (GUT189_06460) - 722364..722780 (+) 417 WP_120171525.1 F0F1 ATP synthase subunit epsilon -
  L6411_RS03510 - 722944..723171 (+) 228 WP_120171526.1 DUF1146 family protein -
  L6411_RS03515 (GUT189_06470) murA 723193..724476 (+) 1284 WP_155969961.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  L6411_RS03520 (GUT189_06480) - 724469..724660 (+) 192 WP_120171528.1 DNA-directed RNA polymerase subunit beta -
  L6411_RS03525 (GUT189_06490) endA 724690..725532 (+) 843 WP_272877493.1 DNA/RNA non-specific endonuclease Machinery gene
  L6411_RS03530 (GUT189_06500) - 725721..727274 (+) 1554 WP_120171530.1 MFS transporter -
  L6411_RS03535 (GUT189_06510) - 727518..728546 (+) 1029 WP_237374397.1 sugar kinase -
  L6411_RS03540 (GUT189_06520) uidA 728562..730352 (+) 1791 WP_237374398.1 beta-glucuronidase -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 30415.10 Da        Isoelectric Point: 10.0305

>NTDB_id=91241 L6411_RS03525 WP_272877493.1 724690..725532(+) (endA) [Streptococcus ruminantium strain GUT-189]
MAKKNVKKQAMSLFSLLATLIVVGGGYFLSSTTNSNVTNHPYYVNQSKASESVPSQELASSVLTENVKKQLGTKIEWNGA
GAFFINGNKTNLDASVASAPYGENKTKIVQGKMVPTVANALLAKSTRQYKDRDETGKGRTSWTPAGWHQIHGLSGEYDHA
VDRGHLLGYALIGGLSGFDASTSNPKNIAVQTAWSNQANDQASTGQNYFESQIRRALDKNKRVRYRVTLIYAEDNDLIPV
GSHLEAKAADGSLEFNVFVPNVQSGLSINYRTGKITVNPR

Nucleotide


Download         Length: 843 bp        

>NTDB_id=91241 L6411_RS03525 WP_272877493.1 724690..725532(+) (endA) [Streptococcus ruminantium strain GUT-189]
GTGGCAAAGAAAAATGTAAAAAAACAAGCCATGAGTTTGTTTAGTTTGTTGGCCACACTCATTGTAGTGGGTGGAGGCTA
CTTTCTAAGCAGTACGACGAATAGTAATGTTACGAATCATCCTTACTATGTCAATCAATCCAAAGCTAGTGAATCAGTAC
CAAGTCAAGAATTGGCTAGCTCAGTATTGACAGAAAATGTAAAAAAGCAACTCGGAACTAAGATTGAGTGGAACGGAGCA
GGTGCTTTCTTCATCAATGGGAATAAAACCAATCTAGATGCATCGGTAGCTAGTGCTCCTTATGGAGAAAATAAAACCAA
GATTGTACAGGGAAAAATGGTACCGACGGTTGCAAATGCTCTTTTAGCAAAATCAACCCGTCAGTATAAGGACCGAGATG
AAACAGGAAAGGGGCGTACCTCTTGGACTCCTGCTGGCTGGCATCAGATTCATGGCTTATCAGGGGAATATGATCATGCA
GTTGATCGAGGCCATTTACTAGGCTATGCCTTGATTGGTGGACTTTCTGGTTTTGATGCTTCAACAAGCAATCCTAAGAA
CATAGCTGTTCAGACAGCTTGGTCCAATCAAGCCAATGACCAAGCTTCTACCGGGCAAAATTATTTTGAAAGTCAGATTC
GTCGGGCGTTGGATAAAAATAAGCGTGTCCGCTACCGTGTGACACTGATTTATGCAGAGGACAATGACTTGATTCCAGTT
GGGAGTCATTTAGAAGCAAAAGCAGCAGATGGAAGTCTAGAATTTAATGTTTTTGTGCCAAATGTACAAAGTGGTTTGAG
TATCAATTATCGTACTGGTAAGATTACAGTCAATCCCCGCTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

65.234

91.429

0.596
  endA Streptococcus pneumoniae D39

65.234

91.429

0.596
  endA Streptococcus pneumoniae R6

65.234

91.429

0.596
  endA Streptococcus pneumoniae TIGR4

65.234

91.429

0.596

Multiple sequence alignment