Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   L6419_RS07000 Genome accession   NZ_AP025332
Coordinates   1459665..1460507 (-) Length   280 a.a.
NCBI ID   WP_272877590.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-184     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1454665..1465507
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6419_RS06985 (GUT184_13400) uidA 1454843..1456633 (-) 1791 WP_120171532.1 beta-glucuronidase -
  L6419_RS06990 (GUT184_13410) - 1456649..1457677 (-) 1029 WP_156021079.1 sugar kinase -
  L6419_RS06995 (GUT184_13420) - 1457922..1459475 (-) 1554 WP_120171530.1 MFS transporter -
  L6419_RS07000 (GUT184_13430) endA 1459665..1460507 (-) 843 WP_272877590.1 DNA/RNA non-specific endonuclease Machinery gene
  L6419_RS07005 (GUT184_13440) - 1460537..1460728 (-) 192 WP_120171528.1 DNA-directed RNA polymerase subunit beta -
  L6419_RS07010 (GUT184_13450) murA 1460721..1462004 (-) 1284 WP_155969961.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  L6419_RS07015 - 1462026..1462253 (-) 228 WP_032537890.1 DUF1146 family protein -
  L6419_RS07020 (GUT184_13460) - 1462417..1462833 (-) 417 WP_155970839.1 F0F1 ATP synthase subunit epsilon -
  L6419_RS07025 (GUT184_13470) atpD 1462843..1464249 (-) 1407 WP_024532406.1 F0F1 ATP synthase subunit beta -
  L6419_RS07030 (GUT184_13480) - 1464421..1465299 (-) 879 WP_024532405.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 30424.10 Da        Isoelectric Point: 9.9448

>NTDB_id=91191 L6419_RS07000 WP_272877590.1 1459665..1460507(-) (endA) [Streptococcus ruminantium strain GUT-184]
MAKKNVKKQAMSLFSLLATLIVVGGGYFLSSTTNSNVTNHPYYVNQSKASESVPSQELASSVLTENVKKQLGTKIEWNGA
GAFFINGNKTNLDVSVASAPYGENKTKIVQGKMVPTVANALLAKSTRQYKDRDETGKGRTSWTPAGWHQIHGLSGEYDHA
VDRGHLLGYALIGGLSGFDASTSNPKNIAVQTAWSNQANDQASTGQNYFESQIRRALDKNKRVRYRVTLIYAEDNDLIPV
GSHLEAKAADGSLEFNVFVPNVQSGLSINYRTGKITVNPH

Nucleotide


Download         Length: 843 bp        

>NTDB_id=91191 L6419_RS07000 WP_272877590.1 1459665..1460507(-) (endA) [Streptococcus ruminantium strain GUT-184]
GTGGCAAAGAAAAATGTAAAAAAACAAGCCATGAGTTTGTTTAGTTTGTTGGCCACACTCATTGTAGTGGGTGGAGGCTA
CTTTCTAAGCAGTACGACGAATAGTAATGTTACGAATCATCCTTACTACGTCAATCAATCCAAAGCTAGTGAATCAGTAC
CAAGTCAAGAATTGGCTAGCTCAGTATTGACAGAAAATGTAAAAAAGCAACTCGGAACTAAGATTGAGTGGAACGGAGCA
GGTGCTTTCTTCATCAATGGGAATAAAACCAATCTAGATGTATCGGTAGCTAGTGCTCCTTATGGAGAAAATAAAACCAA
GATTGTACAGGGAAAAATGGTACCGACGGTTGCAAATGCTCTTTTAGCAAAATCAACCCGTCAGTACAAGGACCGAGATG
AAACAGGAAAGGGGCGTACCTCTTGGACTCCTGCTGGCTGGCATCAGATCCATGGCTTATCAGGGGAATATGATCATGCA
GTTGATCGAGGCCATTTACTAGGCTATGCCTTGATTGGTGGGCTTTCTGGTTTTGATGCTTCAACGAGTAATCCTAAGAA
CATAGCTGTTCAGACAGCTTGGTCCAATCAAGCCAATGACCAAGCTTCTACCGGGCAAAATTATTTTGAAAGTCAGATTC
GTCGGGCGTTGGATAAAAATAAGCGTGTCCGCTACCGTGTGACACTGATTTATGCAGAGGACAATGACTTGATTCCAGTT
GGGAGTCATTTAGAAGCAAAAGCAGCAGATGGAAGTCTAGAATTTAATGTTTTTGTTCCAAATGTACAAAGTGGTTTGAG
TATCAATTATCGTACTGGTAAGATTACAGTCAATCCCCACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

64.844

91.429

0.593
  endA Streptococcus pneumoniae D39

64.844

91.429

0.593
  endA Streptococcus pneumoniae R6

64.844

91.429

0.593
  endA Streptococcus pneumoniae TIGR4

64.844

91.429

0.593

Multiple sequence alignment