Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | SE864_RS01115 | Genome accession | NZ_CP138369 |
| Coordinates | 190588..191562 (+) | Length | 324 a.a. |
| NCBI ID | WP_001008570.1 | Uniprot ID | A0AAW6XQQ3 |
| Organism | Streptococcus agalactiae strain SagR31 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 190299..235979 | 190588..191562 | within | 0 |
Gene organization within MGE regions
Location: 190299..235979
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SE864_RS01115 (SE864_01115) | comYH | 190588..191562 (+) | 975 | WP_001008570.1 | class I SAM-dependent methyltransferase | Machinery gene |
| SE864_RS01120 (SE864_01120) | - | 191594..192787 (+) | 1194 | WP_000047535.1 | acetate kinase | - |
| SE864_RS01125 (SE864_01125) | - | 192938..193144 (+) | 207 | WP_000798242.1 | helix-turn-helix transcriptional regulator | - |
| SE864_RS01130 (SE864_01130) | - | 193203..193340 (+) | 138 | WP_001867090.1 | hypothetical protein | - |
| SE864_RS01135 (SE864_01135) | - | 193381..193836 (+) | 456 | WP_000905674.1 | hypothetical protein | - |
| SE864_RS01140 (SE864_01140) | - | 193905..194570 (+) | 666 | WP_000008111.1 | CPBP family intramembrane glutamic endopeptidase | - |
| SE864_RS01145 (SE864_01145) | proC | 194591..195361 (-) | 771 | WP_001867096.1 | pyrroline-5-carboxylate reductase | - |
| SE864_RS01150 (SE864_01150) | pepA | 195431..196498 (-) | 1068 | WP_001281321.1 | glutamyl aminopeptidase | - |
| SE864_RS01155 (SE864_01155) | - | 196683..196922 (-) | 240 | WP_000660181.1 | hypothetical protein | - |
| SE864_RS01160 (SE864_01160) | - | 197083..197367 (+) | 285 | WP_000791272.1 | DUF4651 domain-containing protein | - |
| SE864_RS01165 (SE864_01165) | - | 197364..197687 (+) | 324 | WP_000601792.1 | thioredoxin family protein | - |
| SE864_RS01170 (SE864_01170) | ytpR | 197720..198346 (+) | 627 | WP_000578331.1 | YtpR family tRNA-binding protein | - |
| SE864_RS01175 (SE864_01175) | - | 198400..199116 (-) | 717 | WP_000186183.1 | class I SAM-dependent methyltransferase | - |
| SE864_RS01180 (SE864_01180) | ssbA | 199197..199592 (+) | 396 | WP_000282450.1 | single-stranded DNA-binding protein | Machinery gene |
| SE864_RS01185 (SE864_01185) | - | 199715..200359 (+) | 645 | WP_000416612.1 | HAD family phosphatase | - |
| SE864_RS01190 (SE864_01190) | - | 200386..202131 (+) | 1746 | WP_047198532.1 | LytS/YhcK type 5TM receptor domain-containing protein | - |
| SE864_RS01195 (SE864_01195) | - | 202112..202852 (+) | 741 | WP_000697630.1 | LytTR family DNA-binding domain-containing protein | - |
| SE864_RS01200 (SE864_01200) | - | 203022..203477 (+) | 456 | WP_000683316.1 | CidA/LrgA family protein | - |
| SE864_RS01205 (SE864_01205) | lrgB | 203479..204207 (+) | 729 | WP_000421727.1 | antiholin-like protein LrgB | - |
| SE864_RS01210 (SE864_01210) | - | 204450..206078 (+) | 1629 | WP_000170504.1 | ABC transporter substrate-binding protein | - |
| SE864_RS01215 (SE864_01215) | - | 206191..207168 (+) | 978 | WP_000680644.1 | ABC transporter permease | - |
| SE864_RS01220 (SE864_01220) | - | 207165..207986 (+) | 822 | WP_319099080.1 | ABC transporter permease | - |
| SE864_RS01225 (SE864_01225) | - | 207998..208801 (+) | 804 | WP_000140979.1 | ABC transporter ATP-binding protein | - |
| SE864_RS01230 (SE864_01230) | - | 208785..209411 (+) | 627 | WP_000171304.1 | ABC transporter ATP-binding protein | - |
| SE864_RS01235 (SE864_01235) | treP | 209693..211723 (+) | 2031 | WP_000434610.1 | PTS system trehalose-specific EIIBC component | - |
| SE864_RS01240 (SE864_01240) | treC | 211945..213570 (+) | 1626 | WP_000151014.1 | alpha,alpha-phosphotrehalase | - |
| SE864_RS01245 (SE864_01245) | - | 213790..215826 (+) | 2037 | WP_000228178.1 | BglG family transcription antiterminator | - |
| SE864_RS01250 (SE864_01250) | - | 215829..216113 (+) | 285 | WP_000944235.1 | PTS sugar transporter subunit IIB | - |
| SE864_RS01255 (SE864_01255) | - | 216126..217481 (+) | 1356 | WP_000677351.1 | PTS ascorbate transporter subunit IIC | - |
| SE864_RS01260 (SE864_01260) | - | 217484..218341 (+) | 858 | WP_000203492.1 | transketolase | - |
| SE864_RS01265 (SE864_01265) | - | 218338..219267 (+) | 930 | WP_001203828.1 | transketolase family protein | - |
| SE864_RS01270 (SE864_01270) | - | 219376..220635 (+) | 1260 | WP_001203074.1 | ferric reductase-like transmembrane domain-containing protein | - |
| SE864_RS01275 (SE864_01275) | rpsO | 220723..220992 (+) | 270 | WP_001018249.1 | 30S ribosomal protein S15 | - |
| SE864_RS01280 (SE864_01280) | pnp | 221373..223502 (+) | 2130 | WP_000043857.1 | polyribonucleotide nucleotidyltransferase | - |
| SE864_RS01285 (SE864_01285) | - | 223504..224256 (+) | 753 | WP_000204780.1 | SseB family protein | - |
| SE864_RS01290 (SE864_01290) | cysE | 224265..224849 (+) | 585 | WP_000539954.1 | serine O-acetyltransferase | - |
| SE864_RS01295 (SE864_01295) | - | 224859..225041 (+) | 183 | WP_000656477.1 | hypothetical protein | - |
| SE864_RS01300 (SE864_01300) | cysS | 225038..226381 (+) | 1344 | WP_000591129.1 | cysteine--tRNA ligase | - |
| SE864_RS01305 (SE864_01305) | - | 226374..226760 (+) | 387 | WP_000568029.1 | Mini-ribonuclease 3 | - |
| SE864_RS01310 (SE864_01310) | rlmB | 226863..227618 (+) | 756 | WP_000178023.1 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB | - |
| SE864_RS01315 (SE864_01315) | - | 227615..228133 (+) | 519 | WP_000716636.1 | NYN domain-containing protein | - |
| SE864_RS01320 (SE864_01320) | - | 228226..229086 (+) | 861 | WP_000143135.1 | DegV family protein | - |
| SE864_RS01325 (SE864_01325) | - | 229624..229743 (+) | 120 | Protein_208 | helix-turn-helix transcriptional regulator | - |
| SE864_RS01330 (SE864_01330) | - | 230061..231227 (-) | 1167 | WP_000160598.1 | IS30-like element ISSag9 family transposase | - |
| SE864_RS01335 (SE864_01335) | rplM | 231528..231974 (+) | 447 | WP_001867156.1 | 50S ribosomal protein L13 | - |
| SE864_RS01340 (SE864_01340) | rpsI | 231995..232387 (+) | 393 | WP_000035940.1 | 30S ribosomal protein S9 | - |
| SE864_RS01345 (SE864_01345) | - | 232533..233687 (-) | 1155 | WP_000110711.1 | site-specific integrase | - |
| SE864_RS01350 (SE864_01350) | - | 233742..234260 (-) | 519 | WP_000181342.1 | helix-turn-helix domain-containing protein | - |
| SE864_RS01355 (SE864_01355) | - | 234407..234691 (+) | 285 | WP_001287945.1 | hypothetical protein | - |
| SE864_RS01360 (SE864_01360) | - | 234703..235557 (+) | 855 | WP_000005759.1 | phage replisome organizer N-terminal domain-containing protein | - |
| SE864_RS01365 (SE864_01365) | - | 235568..235858 (+) | 291 | WP_000158581.1 | DUF5962 family protein | - |
Sequence
Protein
Download Length: 324 a.a. Molecular weight: 37100.99 Da Isoelectric Point: 4.4041
>NTDB_id=902335 SE864_RS01115 WP_001008570.1 190588..191562(+) (comYH) [Streptococcus agalactiae strain SagR31]
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDIVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPIGYYPNDDIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIE
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDIVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPIGYYPNDDIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIE
Nucleotide
Download Length: 975 bp
>NTDB_id=902335 SE864_RS01115 WP_001008570.1 190588..191562(+) (comYH) [Streptococcus agalactiae strain SagR31]
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATTGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCCGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAATTGG
CTATTATCCTAATGATGATATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAGAATAG
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATTGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCCGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAATTGG
CTATTATCCTAATGATGATATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAGAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
66.984 |
97.222 |
0.651 |
| comYH | Streptococcus mutans UA140 |
66.984 |
97.222 |
0.651 |