Detailed information NTG0902018

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: SC831_RS07675
• Genome accession: NZ_CP138345
• Coordinates: 1527363..1528199 (-)
• Length: 278 a.a.
• NCBI ID: WP_004049325.1
• Uniprot ID: A0A4V1PRC4
• Organism: Ligilactobacillus murinus strain XYW20210915001
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1522363..1533199

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SC831_RS07645 (SC831_07610)	-	1522954..1523109 (-)	156	WP_405256479.1	hypothetical protein	-
SC831_RS07650 (SC831_07615)	-	1523087..1524223 (-)	1137	WP_004049316.1	sensor histidine kinase	-
SC831_RS07655 (SC831_07620)	-	1524225..1524944 (-)	720	WP_004049317.1	ABC transporter permease	-
SC831_RS07660 (SC831_07625)	-	1524928..1525818 (-)	891	WP_004049319.1	ABC transporter ATP-binding protein	-
SC831_RS07665 (SC831_07630)	-	1525950..1526825 (-)	876	WP_004049321.1	CPBP family intramembrane glutamic endopeptidase	-
SC831_RS07670 (SC831_07635)	-	1527052..1527363 (-)	312	WP_004049323.1	hypothetical protein	-
SC831_RS07675 (SC831_07640)	endA	1527363..1528199 (-)	837	WP_004049325.1	DNA/RNA non-specific endonuclease	Machinery gene
SC831_RS07680 (SC831_07645)	asnA	1528259..1529266 (-)	1008	WP_004049328.1	aspartate--ammonia ligase	-
SC831_RS07685 (SC831_07650)	-	1529447..1530094 (+)	648	WP_004049330.1	nitroreductase	-
SC831_RS07690 (SC831_07655)	-	1530263..1530688 (-)	426	WP_004049332.1	N-acetyltransferase	-
SC831_RS07695 (SC831_07660)	-	1530756..1531142 (+)	387	WP_004049334.1	iron chaperone	-
SC831_RS07700 (SC831_07665)	-	1531914..1532180 (-)	267	WP_004049336.1	hypothetical protein	-
SC831_RS07705 (SC831_07670)	-	1532508..1532687 (-)	180	WP_039936126.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30334.02 Da
• Isoelectric Point: 10.5647

>NTDB_id=902018 SC831_RS07675 WP_004049325.1 1527363..1528199(-) (endA) [Ligilactobacillus murinus strain XYW20210915001]
MKFKKILTGFVAALMLSGAIGAPVTAKATTHYGGWRTHQKNSSSGSGELKKSTPSQQLAQTVLTPDVVKQLGGEQNLKWN
NSGAFIVNNNKTGLKAKVSSAPYATNEVDSLKRPTVANALLNRTTRQYKNRHQTNNGSTKWKPQGFKQLTNLSGAYNHAY
DRGHLLGYALVGNIRGFDASESNPKNIATQTAWANEANAKYSTGQNYYESLVRKALDRNKTVRYRVTNVYSGNNLVPSGA
HLEAKASDGSLEYNVFIPNVQKGLKIDYATGHAIKENN

Nucleotide

• Length: 837 bp

>NTDB_id=902018 SC831_RS07675 WP_004049325.1 1527363..1528199(-) (endA) [Ligilactobacillus murinus strain XYW20210915001]
ATGAAGTTCAAAAAAATATTGACCGGATTTGTGGCAGCTTTGATGCTCAGTGGTGCGATCGGGGCACCGGTAACAGCTAA
AGCAACGACGCACTATGGTGGTTGGCGCACACATCAAAAAAATAGTTCGAGTGGCTCTGGTGAATTAAAAAAGAGCACTC
CATCACAACAATTAGCCCAAACGGTTTTGACGCCGGATGTTGTTAAACAATTAGGCGGTGAGCAAAATCTCAAATGGAAC
AACAGTGGGGCTTTTATCGTTAATAACAACAAGACAGGTTTAAAAGCTAAGGTTTCTAGTGCTCCTTATGCAACAAATGA
AGTCGATAGCTTAAAACGTCCGACGGTAGCTAATGCCCTTTTGAATAGGACAACACGGCAATACAAGAATCGCCACCAAA
CTAATAATGGTTCGACTAAATGGAAACCACAGGGCTTTAAGCAACTCACTAACTTAAGTGGCGCCTACAACCATGCTTAT
GATCGCGGACACTTACTAGGGTATGCTTTAGTGGGAAATATTCGTGGTTTTGATGCTAGTGAGAGCAATCCCAAAAATAT
TGCGACTCAGACAGCTTGGGCTAATGAAGCTAATGCAAAATATTCAACAGGTCAAAACTATTACGAAAGTCTTGTTCGAA
AAGCCTTAGATCGTAATAAGACTGTCCGTTATCGTGTGACAAATGTCTATAGCGGTAATAATTTAGTACCATCAGGCGCT
CATTTAGAAGCTAAAGCAAGTGATGGTTCGTTAGAGTATAATGTTTTTATCCCTAATGTTCAAAAGGGATTAAAGATCGA
CTATGCTACTGGTCATGCGATAAAGGAGAACAACTGA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (82-250)

3D structure

• AlphaFold DB: A0A4V1PRC4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	65.471	80.216	0.525
endA	Streptococcus pneumoniae D39	65.471	80.216	0.525
endA	Streptococcus pneumoniae R6	65.471	80.216	0.525
endA	Streptococcus pneumoniae TIGR4	65.471	80.216	0.525