Detailed information NTG0899576

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: ABFJ85_RS06110
• Genome accession: NZ_CP156175
• Coordinates: 1277044..1279662 (+)
• Length: 872 a.a.
• NCBI ID: WP_000073352.1
• Uniprot ID: P0C1S1
• Organism: Staphylococcus aureus strain CUBIST-50
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1272044..1284662

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABFJ85_RS06085 (ABFJ85_06085)	-	1272926..1273792 (+)	867	WP_000190138.1	2-oxoacid:ferredoxin oxidoreductase subunit beta	-
ABFJ85_RS06090 (ABFJ85_06090)	-	1273886..1274179 (+)	294	WP_000655666.1	MTH1187 family thiamine-binding protein	-
ABFJ85_RS06095 (ABFJ85_06095)	miaB	1274313..1275857 (+)	1545	WP_001001524.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-
ABFJ85_RS06100 (ABFJ85_06100)	-	1275858..1276223 (+)	366	WP_000282386.1	RicAFT regulatory complex protein RicA family protein	-
ABFJ85_RS06105 (ABFJ85_06105)	thiW	1276250..1276741 (+)	492	WP_000842277.1	energy coupling factor transporter S component ThiW	-
ABFJ85_RS06110 (ABFJ85_06110)	hexA	1277044..1279662 (+)	2619	WP_000073352.1	DNA mismatch repair protein MutS	Machinery gene
ABFJ85_RS06115 (ABFJ85_06115)	hexB	1279675..1281684 (+)	2010	WP_000516269.1	DNA mismatch repair endonuclease MutL	Machinery gene
ABFJ85_RS06120 (ABFJ85_06120)	-	1281690..1282232 (+)	543	WP_001077635.1	glycerol-3-phosphate responsive antiterminator	-
ABFJ85_RS06125 (ABFJ85_06125)	-	1282707..1283525 (+)	819	WP_001103743.1	MIP/aquaporin family protein	-

Sequence

Protein

• Length: 872 a.a.
• Molecular weight: 99903.62 Da
• Isoelectric Point: 4.6294

>NTDB_id=899576 ABFJ85_RS06110 WP_000073352.1 1277044..1279662(+) (hexA) [Staphylococcus aureus strain CUBIST-50]
MSNVTPMMQQYLKIKSEYQDCLLFFRLGDFYEMFYEDAKEASRVLEITLTKRDAKKENPIPMCGVPYHSADSYIDTLVNN
GYKVAICEQMEDPKQTKGMVRREVVRIVTPGTVMEQGGVDDKQNNYILSFVMNQPEIALSYCDVSTGELKVTHFNDEATL
LNEITTINPNEVVINDNISDNLKRQINMVTETITVRETLSSEIYSVNQTEHKLMYQATQLLLDYIHHTQKRDLSHIEDVV
QYAAIDYMKMDFYAKRNLELTESIRLKSKKGTLLWLMDETKTPMGARRLKQWIDRPLISKEQIEARLDIVDEFSAHFIER
DTLRTYLNQVYDIERLVGRVSYGNVNARDLIQLKHSISEIPNIKALLNSMNQNTLVQVNQLEPLDDLLDILEQSLVEEPP
ISVKDGGLFKVGFNTQLDEYLEASKNGKTWLAELQAKERQRTGIKSLKISFNKVFGYFIEITRANLQNFEPSEFGYMRKQ
TLSNAERFITDELKEKEDIILGAEDKAIELEYQLFVQLREEVKKYTERLQQQAKIISELDCLQSFAEIAQKYNYTRPSFS
ENKTLELVESRHPVVERVMDYNDYVPNNCRLDNETFIYLITGPNMSGKSTYMRQVAIISIMAQMGAYVPCKEAVLPIFDQ
IFTRIGAADDLVSGKSTFMVEMLEAQKALTYATEDSLIIFDEIGRGTSTYDGLALAQAMIEYVAETSHAKTLFSTHYHEL
TTLDQALPSLKNVHVAANEYKGELIFLHKVKDGAVDDSYGIQVAKLADLPEKVISRAQVILSEFEASAGKKSSISNLKMV
ENEPEINQENLNLSVEETTDTLSQKDFEQASFDLFENDQESEIELQIKNLNLSNMTPIEALVKLSELQNQLK

Nucleotide

• Length: 2619 bp

>NTDB_id=899576 ABFJ85_RS06110 WP_000073352.1 1277044..1279662(+) (hexA) [Staphylococcus aureus strain CUBIST-50]
ATGTCTAATGTTACACCAATGATGCAGCAATATTTAAAAATAAAATCAGAATACCAAGATTGCTTATTATTTTTTAGACT
AGGTGATTTCTATGAAATGTTTTATGAAGATGCCAAGGAGGCATCACGTGTACTTGAAATTACTTTAACTAAAAGAGATG
CTAAAAAAGAAAATCCAATTCCGATGTGTGGTGTTCCGTATCATTCTGCAGATAGTTATATAGATACACTTGTTAATAAT
GGATATAAAGTAGCTATTTGTGAACAGATGGAAGATCCGAAACAAACGAAAGGTATGGTTAGACGTGAGGTAGTAAGAAT
TGTGACTCCAGGAACTGTGATGGAGCAAGGTGGTGTAGATGATAAACAAAATAACTATATTTTAAGTTTTGTTATGAATC
AACCTGAAATTGCGCTTAGTTACTGTGATGTTTCTACTGGCGAATTAAAGGTTACACATTTTAATGATGAAGCGACTTTA
TTAAATGAAATTACGACGATAAACCCTAACGAAGTTGTTATCAATGACAATATTTCCGATAATTTAAAAAGACAAATTAA
TATGGTGACAGAAACAATAACAGTCAGGGAAACGTTATCATCAGAAATCTATAGTGTGAATCAAACTGAACATAAATTAA
TGTATCAAGCGACACAATTATTGCTAGATTATATTCATCATACACAAAAACGTGATTTATCGCATATCGAGGATGTTGTT
CAATATGCAGCTATAGATTATATGAAAATGGATTTTTATGCTAAGAGAAACCTTGAGTTAACGGAAAGCATTCGATTAAA
ATCAAAAAAAGGAACGCTACTTTGGCTAATGGACGAAACGAAAACACCAATGGGAGCACGCCGCTTAAAACAATGGATAG
ATAGACCACTAATAAGTAAAGAACAAATTGAAGCACGATTAGATATCGTTGATGAATTTAGTGCTCATTTCATAGAAAGA
GACACCTTAAGAACATATCTTAATCAAGTGTATGATATTGAACGTCTTGTTGGGCGTGTTAGTTACGGAAATGTTAATGC
GAGAGATTTAATTCAACTTAAACATTCCATTTCTGAAATACCGAATATTAAAGCATTACTAAATTCTATGAATCAGAATA
CGCTTGTACAAGTTAATCAACTAGAACCCCTTGATGATTTACTTGATATATTAGAACAGAGTTTAGTAGAAGAACCACCA
ATTTCAGTTAAAGATGGCGGACTATTCAAAGTTGGTTTTAATACGCAATTAGATGAATATCTTGAAGCTTCAAAAAACGG
AAAAACATGGTTAGCAGAATTACAAGCCAAAGAAAGACAACGTACAGGAATAAAATCATTGAAAATAAGCTTTAATAAAG
TGTTTGGTTATTTTATAGAAATAACACGTGCCAACTTGCAAAATTTTGAACCAAGTGAATTTGGTTATATGAGGAAGCAA
ACGTTATCGAATGCTGAACGTTTTATAACTGATGAACTTAAAGAAAAAGAAGATATCATTTTAGGTGCGGAAGACAAAGC
CATCGAATTAGAATATCAATTATTTGTTCAGCTACGTGAAGAAGTTAAAAAATATACTGAACGTTTACAACAACAAGCTA
AAATTATTTCAGAGCTAGATTGTTTACAGAGCTTTGCAGAAATTGCTCAAAAATATAATTACACTAGGCCTTCATTTAGT
GAAAATAAAACATTAGAATTAGTGGAATCTAGGCACCCAGTAGTGGAAAGAGTAATGGATTATAATGACTATGTGCCTAA
TAATTGTCGATTAGATAATGAAACATTTATATATTTAATTACAGGTCCGAATATGTCTGGTAAATCGACATATATGAGAC
AAGTTGCCATAATTAGTATAATGGCCCAAATGGGAGCTTATGTCCCTTGTAAAGAGGCAGTGTTACCTATATTTGATCAA
ATATTCACTAGAATAGGTGCGGCAGATGATTTGGTTTCAGGTAAGAGTACGTTTATGGTAGAAATGCTAGAAGCACAAAA
GGCATTAACTTATGCAACAGAGGATAGTTTGATTATTTTCGATGAAATTGGACGTGGTACTTCAACGTATGACGGTTTAG
CTTTAGCGCAGGCAATGATAGAGTATGTAGCTGAAACATCGCATGCTAAAACGTTATTTTCAACACATTATCATGAATTG
ACAACATTAGATCAAGCATTACCAAGTCTAAAAAATGTTCACGTCGCTGCTAATGAATATAAAGGTGAACTTATATTCTT
GCATAAAGTCAAAGATGGTGCAGTTGACGATAGTTATGGTATTCAAGTTGCGAAATTAGCTGATTTACCTGAAAAAGTTA
TTAGCAGAGCACAAGTGATCCTAAGCGAGTTTGAAGCGTCTGCTGGTAAAAAATCATCGATATCAAATTTAAAAATGGTC
GAAAATGAACCTGAAATTAATCAAGAAAATTTAAACTTAAGTGTTGAAGAAACAACTGATACTTTATCTCAAAAAGACTT
TGAACAAGCATCATTTGATTTGTTTGAAAATGATCAAGAAAGCGAGATTGAACTACAAATTAAAAATTTGAATTTATCTA
ATATGACACCAATTGAGGCATTGGTGAAGTTAAGTGAATTACAAAATCAATTAAAATAG

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (412-505)

• MutS domain I (MutS_I) (5-115)

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (125-237)

3D structure

• AlphaFold DB: P0C1S1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	45.455	100	0.459