Detailed information NTG0895909

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: R4712_RS10415
• Genome accession: NZ_CP137110
• Coordinates: 2000126..2000974 (+)
• Length: 282 a.a.
• NCBI ID: WP_044812295.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 16H2041
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1995126..2005974

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4712_RS10390	-	1995841..1996548 (+)	708	WP_000638502.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
R4712_RS10395	-	1996553..1997575 (+)	1023	WP_000609894.1	ribitol-5-phosphate dehydrogenase	-
R4712_RS10400	licA	1997592..1998461 (+)	870	WP_000411210.1	choline kinase LicA	-
R4712_RS10405	-	1998451..1999329 (+)	879	WP_000837609.1	DMT family transporter	-
R4712_RS10410	-	1999341..2000030 (+)	690	WP_000643970.1	sugar phosphate nucleotidyltransferase	-
R4712_RS10415	dprA/cilB/dalA	2000126..2000974 (+)	849	WP_044812295.1	DNA-processing protein DprA	Machinery gene
R4712_RS10420	-	2001158..2001280 (-)	123	WP_001814242.1	hypothetical protein	-
R4712_RS10425	-	2001858..2002901 (+)	1044	WP_001812957.1	TIGR00341 family protein	-
R4712_RS10430	topA	2003068..2005155 (+)	2088	WP_000179652.1	type I DNA topoisomerase	-
R4712_RS10435	-	2005261..2005620 (+)	360	WP_001237218.1	YbaN family protein	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31092.75 Da
• Isoelectric Point: 5.4047

>NTDB_id=895909 R4712_RS10415 WP_044812295.1 2000126..2000974(+) (dprA/cilB/dalA) [Streptococcus pneumoniae strain 16H2041]
MKITNYEIYKLKKSSLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=895909 R4712_RS10415 WP_044812295.1 2000126..2000974(+) (dprA/cilB/dalA) [Streptococcus pneumoniae strain 16H2041]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAAGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.645	100	0.996
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	98.227	100	0.982
dprA/cilB/dalA	Streptococcus mitis SK321	97.518	100	0.975
dprA	Streptococcus mutans UA159	62.857	99.291	0.624
dprA	Lactococcus lactis subsp. cremoris KW2	55.357	99.291	0.55
dprA	Staphylococcus aureus N315	37.809	100	0.379
dprA	Haemophilus influenzae Rd KW20	38.202	94.681	0.362