Detailed information NTG0895756

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: R4715_RS10745
• Genome accession: NZ_CP137108
• Coordinates: 2057708..2058661 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain OXT
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2052708..2063661

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4715_RS10720	rpmG	2053451..2053600 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
R4715_RS10725	secG	2053640..2053873 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
R4715_RS10730	rnr	2053975..2056329 (+)	2355	WP_061742425.1	ribonuclease R	-
R4715_RS10735	smpB	2056292..2056759 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
R4715_RS10740	tehB	2056775..2057635 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
R4715_RS10745	coiA	2057708..2058661 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
R4715_RS10750	pepF	2058680..2060482 (+)	1803	WP_001864211.1	oligoendopeptidase F	Regulator
R4715_RS10755	-	2060484..2061197 (+)	714	WP_000230399.1	O-methyltransferase	-
R4715_RS10760	prsA	2061264..2062205 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
R4715_RS10765	-	2062322..2062663 (-)	342	Protein_2081	transposase	-
R4715_RS10770	-	2063075..2063170 (+)	96	Protein_2082	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=895756 R4715_RS10745 WP_000495909.1 2057708..2058661(+) (coiA) [Streptococcus pneumoniae strain OXT]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=895756 R4715_RS10745 WP_000495909.1 2057708..2058661(+) (coiA) [Streptococcus pneumoniae strain OXT]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435