Detailed information
Bioinformatically predicted
Overview
| Name | comA | Type | Regulator |
| Locus tag | R0Q59_RS02885 | Genome accession | NZ_CP136658 |
| Coordinates | 582723..584882 (+) | Length | 719 a.a. |
| NCBI ID | WP_411163213.1 | Uniprot ID | - |
| Organism | Lactobacillus johnsonii strain GJ231 | ||
| Function | processing and transport of ComC (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 574804..599357 | 582723..584882 | within | 0 |
| IS/Tn | 581119..582168 | 582723..584882 | flank | 555 |
Gene organization within MGE regions
Location: 574804..599357
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| R0Q59_RS02835 (R0Q59_02835) | - | 574804..574956 (+) | 153 | WP_004896917.1 | hypothetical protein | - |
| R0Q59_RS02840 (R0Q59_02840) | - | 574959..576254 (+) | 1296 | WP_216512746.1 | GHKL domain-containing protein | - |
| R0Q59_RS02845 (R0Q59_02845) | - | 576261..577058 (+) | 798 | WP_004896923.1 | LytR/AlgR family response regulator transcription factor | - |
| R0Q59_RS02850 (R0Q59_02850) | comA | 577071..579230 (+) | 2160 | WP_411163211.1 | peptide cleavage/export ABC transporter | Regulator |
| R0Q59_RS02855 (R0Q59_02855) | - | 579241..579834 (+) | 594 | WP_011161710.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| R0Q59_RS02860 (R0Q59_02860) | - | 579961..580188 (+) | 228 | WP_014567249.1 | bacteriocin class II family protein | - |
| R0Q59_RS02865 (R0Q59_02865) | - | 580199..580387 (+) | 189 | WP_011161712.1 | Blp family class II bacteriocin | - |
| R0Q59_RS02870 (R0Q59_02870) | - | 580474..580848 (+) | 375 | WP_011161713.1 | hypothetical protein | - |
| R0Q59_RS02875 (R0Q59_02875) | - | 581119..582168 (+) | 1050 | WP_411163212.1 | IS30-like element ISLjo1 family transposase | - |
| R0Q59_RS02880 (R0Q59_02880) | - | 582306..582710 (+) | 405 | WP_241033140.1 | LytTR family DNA-binding domain-containing protein | - |
| R0Q59_RS02885 (R0Q59_02885) | comA | 582723..584882 (+) | 2160 | WP_411163213.1 | peptide cleavage/export ABC transporter | Regulator |
| R0Q59_RS02890 (R0Q59_02890) | - | 584893..585486 (+) | 594 | WP_011161717.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| R0Q59_RS02895 (R0Q59_02895) | - | 585636..585830 (+) | 195 | WP_011161718.1 | hypothetical protein | - |
| R0Q59_RS02900 (R0Q59_02900) | - | 585943..586233 (+) | 291 | WP_411163214.1 | bacteriocin immunity protein | - |
| R0Q59_RS02905 (R0Q59_02905) | - | 586318..587550 (+) | 1233 | WP_011161720.1 | CPBP family intramembrane glutamic endopeptidase | - |
| R0Q59_RS02910 (R0Q59_02910) | - | 587646..587942 (+) | 297 | WP_411163215.1 | hypothetical protein | - |
| R0Q59_RS02915 (R0Q59_02915) | - | 588125..588355 (+) | 231 | WP_153939030.1 | hypothetical protein | - |
| R0Q59_RS02920 (R0Q59_02920) | - | 588479..588793 (+) | 315 | WP_411163216.1 | bacteriocin immunity protein | - |
| R0Q59_RS02925 (R0Q59_02925) | - | 588802..589080 (+) | 279 | WP_411163217.1 | hypothetical protein | - |
| R0Q59_RS02930 (R0Q59_02930) | - | 589144..590868 (+) | 1725 | Protein_568 | cation-translocating P-type ATPase | - |
| R0Q59_RS02935 | - | 590872..591045 (+) | 174 | WP_411163299.1 | cation transporting ATPase C-terminal domain-containing protein | - |
| R0Q59_RS02940 (R0Q59_02935) | - | 591117..591965 (+) | 849 | WP_014567258.1 | patatin family protein | - |
| R0Q59_RS02945 (R0Q59_02940) | - | 592066..593559 (+) | 1494 | WP_069168995.1 | ABC transporter substrate-binding protein/permease | - |
| R0Q59_RS02950 (R0Q59_02945) | - | 593546..594277 (+) | 732 | WP_004896938.1 | amino acid ABC transporter ATP-binding protein | - |
| R0Q59_RS02955 (R0Q59_02950) | - | 594373..594894 (+) | 522 | WP_004896939.1 | GNAT family N-acetyltransferase | - |
| R0Q59_RS02960 (R0Q59_02955) | - | 595012..595881 (+) | 870 | WP_004896940.1 | phosphate ABC transporter substrate-binding protein | - |
| R0Q59_RS02965 (R0Q59_02960) | pstC | 595898..596890 (+) | 993 | WP_011161729.1 | phosphate ABC transporter permease subunit PstC | - |
| R0Q59_RS02970 (R0Q59_02965) | pstA | 596890..597780 (+) | 891 | WP_004896942.1 | phosphate ABC transporter permease PstA | - |
| R0Q59_RS02975 (R0Q59_02970) | pstB | 597791..598591 (+) | 801 | WP_004896943.1 | phosphate ABC transporter ATP-binding protein PstB | - |
| R0Q59_RS02980 (R0Q59_02975) | pstB | 598602..599357 (+) | 756 | WP_011161731.1 | phosphate ABC transporter ATP-binding protein PstB | - |
Sequence
Protein
Download Length: 719 a.a. Molecular weight: 81176.32 Da Isoelectric Point: 6.5144
>NTDB_id=892291 R0Q59_RS02885 WP_411163213.1 582723..584882(+) (comA) [Lactobacillus johnsonii strain GJ231]
MLFKYKSVYVPQVDEMDCGVACLAMILKQYQSRVSLAHLRHEARTNLEGTTALGLVKTAQKFNFKTEAVKADMSLFNEDT
IQYPFIVHVLKQEELLHYYVVLKNTKHYLVIADPDPSVGIIKMPKDKFAQEWTGIALFMVPNEDFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYIFNSIFSYGQNFLLNVLGQRLSI
DLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLAIVIVMGLVLAAQNTTLFGITLLALPVYA
IVILGFTKKFEKLNDEQMESNAVLSSSVIEDIQGIETIKALNSEDTRYRRIDSQFVNYLKKSFKYSKTESLQTALKTFIQ
LSLNVIILWVGARVVMQGEMSIGQLMTFNALLSYFIDPLQNIINLQPRLQSASVAQNRLNEVYQVQSEFNADTSIQNSAA
LEGMIEYKHVDYRYGYGTDVLKDINLKIKSDEKLAIVGMSGSGKSTMVKLLVDFFSPSKGEVTLNGHATSEVNKHTLRSY
VNYVPQTPYIFSGTVKENLLLGCRADISEEEVIKACQIAGIDQEIANLPLQFETKLDENAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKRVVDNLMKLKDKTIIFIAHRLAIAERADKVVVIDKGQIVEEGSHEELMEQHGFYYDLVKG
MLFKYKSVYVPQVDEMDCGVACLAMILKQYQSRVSLAHLRHEARTNLEGTTALGLVKTAQKFNFKTEAVKADMSLFNEDT
IQYPFIVHVLKQEELLHYYVVLKNTKHYLVIADPDPSVGIIKMPKDKFAQEWTGIALFMVPNEDFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYIFNSIFSYGQNFLLNVLGQRLSI
DLNLQYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLAIVIVMGLVLAAQNTTLFGITLLALPVYA
IVILGFTKKFEKLNDEQMESNAVLSSSVIEDIQGIETIKALNSEDTRYRRIDSQFVNYLKKSFKYSKTESLQTALKTFIQ
LSLNVIILWVGARVVMQGEMSIGQLMTFNALLSYFIDPLQNIINLQPRLQSASVAQNRLNEVYQVQSEFNADTSIQNSAA
LEGMIEYKHVDYRYGYGTDVLKDINLKIKSDEKLAIVGMSGSGKSTMVKLLVDFFSPSKGEVTLNGHATSEVNKHTLRSY
VNYVPQTPYIFSGTVKENLLLGCRADISEEEVIKACQIAGIDQEIANLPLQFETKLDENAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKRVVDNLMKLKDKTIIFIAHRLAIAERADKVVVIDKGQIVEEGSHEELMEQHGFYYDLVKG
Nucleotide
Download Length: 2160 bp
>NTDB_id=892291 R0Q59_RS02885 WP_411163213.1 582723..584882(+) (comA) [Lactobacillus johnsonii strain GJ231]
ATGTTATTCAAATATAAATCTGTTTATGTACCTCAAGTAGATGAGATGGATTGCGGAGTTGCTTGTCTAGCAATGATCTT
AAAGCAGTATCAATCTCGTGTGTCTTTAGCACATTTGCGTCACGAAGCTCGCACAAATCTTGAAGGCACAACTGCGCTGG
GACTAGTTAAAACAGCACAGAAATTTAATTTTAAAACTGAAGCCGTAAAAGCTGATATGTCTCTTTTTAATGAGGATACT
ATTCAATACCCTTTTATCGTGCATGTTCTTAAGCAAGAAGAATTACTTCATTATTACGTAGTTCTTAAAAATACTAAGCA
TTACTTAGTAATTGCCGATCCTGATCCATCAGTTGGCATAATAAAGATGCCTAAAGATAAATTTGCTCAAGAATGGACTG
GTATTGCGCTTTTTATGGTTCCGAATGAAGATTTTGAACCAATTAAAGAAAAGAAAAATAACCTATGGTCTCTCTTTCCA
TATATGTTTAAGCAAAAGCGGCTGATGATTAATATCATTTTAGCCGCTTTATTAATGACAATAATTAGTATTTGTAGTTC
ATACTTTGTGCAAGGAATAATCGATACTTATATTCCCGATGGAACTTATCAGACTCTTTCAATTTTAGCTGTTGGACTAT
TAATTGCTTATATTTTTAATTCAATCTTTTCTTATGGACAGAATTTTTTATTAAATGTTCTAGGTCAAAGATTAAGTATT
GATTTAAACCTCCAATATATAAGGCATATTTTTGAATTGCCAATGGAATTCTTTGTGACTAGAAGAACTGGTGAAATAAC
CTCACGTTTCTCTGATGCAAGTAGAATTATTGATGCTCTAGCAAGTACTGTTATTTCACTTTTCTTAGACTTAGCGATTG
TAATTGTAATGGGACTAGTGTTAGCTGCTCAAAATACAACATTATTTGGGATCACATTATTAGCTTTACCAGTGTATGCG
ATAGTAATTCTAGGATTTACTAAGAAATTTGAAAAATTAAATGATGAACAGATGGAGAGTAATGCAGTACTAAGTTCTTC
AGTTATCGAAGATATTCAAGGTATTGAAACTATCAAAGCTCTCAATAGTGAAGATACAAGATATCGCAGAATCGATAGTC
AATTTGTAAACTATTTAAAGAAGTCATTTAAATATAGTAAGACTGAGAGTTTGCAGACGGCCTTAAAGACATTTATTCAA
CTATCTCTTAATGTAATTATTTTATGGGTTGGAGCAAGAGTAGTGATGCAAGGAGAGATGAGTATTGGTCAATTAATGAC
TTTTAATGCATTACTATCTTATTTCATTGACCCACTTCAAAATATTATTAACTTACAACCTCGGCTTCAATCTGCGAGTG
TTGCACAAAATAGATTGAACGAGGTTTATCAGGTGCAAAGTGAATTTAATGCAGATACTTCTATCCAGAACTCAGCTGCT
TTAGAAGGAATGATTGAATACAAGCATGTTGATTATCGATATGGTTATGGTACTGATGTTTTAAAAGATATTAATCTAAA
AATTAAGTCAGATGAAAAATTAGCAATTGTTGGAATGAGTGGATCAGGAAAATCGACGATGGTTAAGTTACTCGTTGATT
TCTTTTCACCAAGTAAGGGAGAAGTAACTTTAAATGGTCATGCAACTAGTGAAGTTAATAAACATACCTTACGCTCGTAT
GTTAACTATGTTCCTCAAACGCCATATATCTTTTCTGGAACAGTTAAGGAGAATTTATTACTGGGATGTAGAGCTGATAT
TAGCGAAGAAGAGGTAATTAAAGCCTGTCAGATTGCTGGCATTGATCAGGAGATAGCTAATTTGCCCCTACAATTTGAGA
CAAAGTTAGATGAGAATGCGAAGATTTTATCAGGTGGACAAAAGCAGAGATTAACTATTGCTAGAGCATTACTTTCGCCA
GCAAAAGTTTTTATCTTTGATGAAGTAACAAGTGGTTTAGATACAATTACAGAAAAAAGAGTAGTTGACAATCTTATGAA
ACTAAAAGACAAGACAATCATTTTTATTGCACACCGTCTAGCCATTGCGGAACGTGCAGATAAGGTCGTTGTAATTGACA
AGGGGCAGATTGTTGAAGAAGGAAGTCATGAAGAGCTTATGGAGCAACATGGTTTTTATTATGACTTAGTAAAGGGATAG
ATGTTATTCAAATATAAATCTGTTTATGTACCTCAAGTAGATGAGATGGATTGCGGAGTTGCTTGTCTAGCAATGATCTT
AAAGCAGTATCAATCTCGTGTGTCTTTAGCACATTTGCGTCACGAAGCTCGCACAAATCTTGAAGGCACAACTGCGCTGG
GACTAGTTAAAACAGCACAGAAATTTAATTTTAAAACTGAAGCCGTAAAAGCTGATATGTCTCTTTTTAATGAGGATACT
ATTCAATACCCTTTTATCGTGCATGTTCTTAAGCAAGAAGAATTACTTCATTATTACGTAGTTCTTAAAAATACTAAGCA
TTACTTAGTAATTGCCGATCCTGATCCATCAGTTGGCATAATAAAGATGCCTAAAGATAAATTTGCTCAAGAATGGACTG
GTATTGCGCTTTTTATGGTTCCGAATGAAGATTTTGAACCAATTAAAGAAAAGAAAAATAACCTATGGTCTCTCTTTCCA
TATATGTTTAAGCAAAAGCGGCTGATGATTAATATCATTTTAGCCGCTTTATTAATGACAATAATTAGTATTTGTAGTTC
ATACTTTGTGCAAGGAATAATCGATACTTATATTCCCGATGGAACTTATCAGACTCTTTCAATTTTAGCTGTTGGACTAT
TAATTGCTTATATTTTTAATTCAATCTTTTCTTATGGACAGAATTTTTTATTAAATGTTCTAGGTCAAAGATTAAGTATT
GATTTAAACCTCCAATATATAAGGCATATTTTTGAATTGCCAATGGAATTCTTTGTGACTAGAAGAACTGGTGAAATAAC
CTCACGTTTCTCTGATGCAAGTAGAATTATTGATGCTCTAGCAAGTACTGTTATTTCACTTTTCTTAGACTTAGCGATTG
TAATTGTAATGGGACTAGTGTTAGCTGCTCAAAATACAACATTATTTGGGATCACATTATTAGCTTTACCAGTGTATGCG
ATAGTAATTCTAGGATTTACTAAGAAATTTGAAAAATTAAATGATGAACAGATGGAGAGTAATGCAGTACTAAGTTCTTC
AGTTATCGAAGATATTCAAGGTATTGAAACTATCAAAGCTCTCAATAGTGAAGATACAAGATATCGCAGAATCGATAGTC
AATTTGTAAACTATTTAAAGAAGTCATTTAAATATAGTAAGACTGAGAGTTTGCAGACGGCCTTAAAGACATTTATTCAA
CTATCTCTTAATGTAATTATTTTATGGGTTGGAGCAAGAGTAGTGATGCAAGGAGAGATGAGTATTGGTCAATTAATGAC
TTTTAATGCATTACTATCTTATTTCATTGACCCACTTCAAAATATTATTAACTTACAACCTCGGCTTCAATCTGCGAGTG
TTGCACAAAATAGATTGAACGAGGTTTATCAGGTGCAAAGTGAATTTAATGCAGATACTTCTATCCAGAACTCAGCTGCT
TTAGAAGGAATGATTGAATACAAGCATGTTGATTATCGATATGGTTATGGTACTGATGTTTTAAAAGATATTAATCTAAA
AATTAAGTCAGATGAAAAATTAGCAATTGTTGGAATGAGTGGATCAGGAAAATCGACGATGGTTAAGTTACTCGTTGATT
TCTTTTCACCAAGTAAGGGAGAAGTAACTTTAAATGGTCATGCAACTAGTGAAGTTAATAAACATACCTTACGCTCGTAT
GTTAACTATGTTCCTCAAACGCCATATATCTTTTCTGGAACAGTTAAGGAGAATTTATTACTGGGATGTAGAGCTGATAT
TAGCGAAGAAGAGGTAATTAAAGCCTGTCAGATTGCTGGCATTGATCAGGAGATAGCTAATTTGCCCCTACAATTTGAGA
CAAAGTTAGATGAGAATGCGAAGATTTTATCAGGTGGACAAAAGCAGAGATTAACTATTGCTAGAGCATTACTTTCGCCA
GCAAAAGTTTTTATCTTTGATGAAGTAACAAGTGGTTTAGATACAATTACAGAAAAAAGAGTAGTTGACAATCTTATGAA
ACTAAAAGACAAGACAATCATTTTTATTGCACACCGTCTAGCCATTGCGGAACGTGCAGATAAGGTCGTTGTAATTGACA
AGGGGCAGATTGTTGAAGAAGGAAGTCATGAAGAGCTTATGGAGCAACATGGTTTTTATTATGACTTAGTAAAGGGATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comA | Streptococcus mitis NCTC 12261 |
56.461 |
99.026 |
0.559 |
| comA | Streptococcus mitis SK321 |
56.18 |
99.026 |
0.556 |
| comA | Streptococcus pneumoniae Rx1 |
56.039 |
99.026 |
0.555 |
| comA | Streptococcus pneumoniae D39 |
56.039 |
99.026 |
0.555 |
| comA | Streptococcus pneumoniae R6 |
56.039 |
99.026 |
0.555 |
| comA | Streptococcus pneumoniae TIGR4 |
55.899 |
99.026 |
0.554 |
| comA | Streptococcus gordonii str. Challis substr. CH1 |
54.916 |
99.026 |
0.544 |
| comA/nlmT | Streptococcus mutans UA159 |
53.182 |
98.331 |
0.523 |