Detailed information NTG0088602

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: K6J74_RS05565
• Genome accession: NZ_AP024819
• Coordinates: 1090462..1092807 (+)
• Length: 781 a.a.
• NCBI ID: WP_221271292.1
• Uniprot ID: -
• Organism: Helicobacter sp. NHP19-012
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1085462..1097807

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6J74_RS05545 (NHP190012_11410)	-	1086647..1086865 (+)	219	WP_221271288.1	hypothetical protein	-
K6J74_RS05550 (NHP190012_11420)	-	1086874..1087311 (+)	438	WP_221271289.1	hypothetical protein	-
K6J74_RS05555 (NHP190012_11430)	-	1087460..1088158 (+)	699	WP_221271290.1	flagellar hook-length control protein FliK	-
K6J74_RS05560 (NHP190012_11440)	-	1088387..1090453 (+)	2067	WP_221271291.1	polysaccharide lyase family 8 super-sandwich domain-containing protein	-
K6J74_RS05565 (NHP190012_11450)	comB4	1090462..1092807 (+)	2346	WP_221271292.1	transporter	Machinery gene
K6J74_RS05570 (NHP190012_11460)	pseB	1092845..1093834 (+)	990	WP_221271293.1	UDP-N-acetylglucosamine 4,6-dehydratase (inverting)	-
K6J74_RS05575 (NHP190012_11470)	coaBC	1093824..1095053 (+)	1230	WP_221271294.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
K6J74_RS05580 (NHP190012_11480)	-	1095110..1095484 (+)	375	WP_221271295.1	hypothetical protein	-
K6J74_RS05585 (NHP190012_11490)	-	1095481..1095645 (-)	165	WP_221271296.1	hypothetical protein	-
K6J74_RS05590 (NHP190012_11500)	-	1096024..1096173 (-)	150	WP_221271297.1	hypothetical protein	-
K6J74_RS08635 (NHP190012_11510)	-	1096438..1096560 (-)	123	WP_260321543.1	hypothetical protein	-
K6J74_RS05595 (NHP190012_11520)	-	1096569..1096829 (-)	261	WP_221271298.1	hypothetical protein	-
K6J74_RS08640	-	1096829..1096960 (-)	132	WP_260321544.1	hypothetical protein	-
K6J74_RS05600 (NHP190012_11530)	-	1097066..1097716 (+)	651	WP_221271299.1	IS607 family transposase	-

Sequence

Protein

• Length: 781 a.a.
• Molecular weight: 87745.71 Da
• Isoelectric Point: 7.4070

>NTDB_id=88602 K6J74_RS05565 WP_221271292.1 1090462..1092807(+) (comB4) [Helicobacter sp. NHP19-012]
MKFGLEFWRHKALDLLAGALPKTHSMAEENNILGLYNERFLLTKSEQLVGLLNIEGLSVNALLQEDLQTHFSSKQNALEQ
LEGVVLRIHTKRAKIQLEPPSKPQNPQVQALLDLSQPKDLYENTYTLIFETTQSPLKDFLEQKKLELITDHKTHQHLAQH
LSASMEQMAHALSAFKPTPLSAKEVLNFYASFINGHPTKLNPTLGFLEDSYIATNIHFNKDHYIQEHATHTTYNRILGVK
AYASKTLSSLALLSLLHQELACEVFLSLEPLSTQAALAFVQEKIRLSFARLVRQELQSYYEQIQAKRLRLQKAALNIILK
APDLQSLNAHTKEVLSVLANAHLVGVVETLGLRPAFFSLFPGRLHLNPRLRCQSAQALATLMLFEKPNCGFKSNPWGNQP
LSVFKNLDHSPYLFNFHNQESDPNPNSPRTNGHTMIIGATGAGKTTLMGFLMANALKYDKLNILALDRAYGLFSCINYFG
GVYNSGKDFKINPLTLELTPSNQDFLHSFYSSLCHLSAHPQNKEDIHASHALLKALKSLHATLPQKSFNLQDLKEAITNA
PNLHLSLESYLQNPLFNALEDSLEFDTPLAAINMDAISANPKDLGLLAYYIFYKILHRALEKQEGFLLFVDEFKSYAQNE
TLNTHINTLITQARKANGVVVLALQDTNQLASIPEAASFVKNMGTLIFYPQKHIDSTLLSKDLGIQLSYMEAHFLENTPL
TAKQVLVKNMAEGSSNIIHVDLQDLGTHLRIFNSNAAHVKRLQALMQAYPETWREVLLQEG

Nucleotide

• Length: 2346 bp

>NTDB_id=88602 K6J74_RS05565 WP_221271292.1 1090462..1092807(+) (comB4) [Helicobacter sp. NHP19-012]
TTGAAATTTGGCTTAGAGTTTTGGCGGCATAAAGCCCTAGATCTCTTGGCCGGTGCGTTGCCAAAAACCCACTCCATGGC
AGAAGAGAACAACATTCTCGGGCTTTACAACGAACGCTTTTTGCTCACCAAGAGCGAGCAGCTTGTGGGGCTCTTAAACA
TTGAGGGTTTGAGCGTAAACGCCCTCTTGCAAGAGGATTTGCAAACCCACTTCTCTAGCAAGCAAAACGCCCTAGAGCAA
CTCGAGGGCGTGGTGCTGCGTATCCACACCAAGCGCGCCAAAATCCAGCTAGAGCCCCCAAGTAAGCCGCAAAACCCCCA
AGTGCAAGCCCTACTTGATTTGTCCCAGCCCAAAGACTTATACGAGAACACCTACACGCTCATTTTTGAAACCACGCAAA
GCCCCCTAAAGGACTTTTTAGAGCAGAAAAAACTAGAACTCATAACAGACCACAAAACGCACCAACACCTAGCCCAGCAC
TTAAGCGCGAGCATGGAGCAAATGGCGCACGCCCTAAGTGCCTTCAAGCCCACCCCCCTAAGCGCAAAGGAAGTTCTAAA
CTTTTATGCCTCCTTCATCAACGGACACCCCACAAAGTTAAACCCCACCCTAGGCTTTTTAGAAGACAGCTACATCGCCA
CGAACATCCATTTTAACAAAGACCACTACATCCAAGAGCACGCCACCCACACGACCTACAACCGCATTTTGGGCGTGAAA
GCCTATGCGAGCAAGACTCTAAGCTCGCTCGCCCTGCTCTCTTTGTTGCATCAAGAGCTCGCATGCGAAGTGTTTTTAAG
CTTGGAGCCCTTAAGCACCCAAGCCGCCCTAGCCTTCGTGCAAGAGAAAATCCGCCTAAGTTTCGCCCGCCTTGTGCGCC
AAGAGTTGCAAAGCTATTACGAGCAGATCCAAGCCAAACGCCTACGCTTGCAAAAAGCCGCCTTAAATATCATTCTCAAA
GCCCCCGATTTACAAAGCCTCAACGCCCACACCAAGGAAGTTTTAAGCGTGCTTGCTAACGCCCACTTGGTGGGGGTGGT
GGAGACTTTGGGGCTAAGACCGGCCTTTTTCTCTCTATTTCCCGGGCGTTTGCATTTAAACCCCCGCCTGCGCTGCCAAA
GCGCACAAGCCCTAGCCACGCTCATGCTCTTTGAAAAACCAAATTGCGGCTTTAAAAGCAACCCTTGGGGCAACCAGCCC
TTAAGCGTGTTTAAGAATTTAGACCATTCCCCCTATCTCTTCAACTTCCACAACCAAGAGAGCGACCCAAACCCCAATAG
CCCACGCACCAACGGGCACACGATGATCATCGGGGCAACAGGGGCGGGCAAGACCACCTTAATGGGCTTTTTAATGGCAA
ATGCGCTCAAATACGACAAGCTCAACATTTTGGCTTTAGATCGTGCCTATGGGCTGTTTTCGTGTATAAATTACTTTGGT
GGGGTGTATAACTCTGGCAAGGATTTTAAAATCAACCCCCTAACTTTAGAGCTCACGCCCAGTAACCAAGACTTTTTACA
CAGCTTTTACTCTAGCCTATGTCATTTGAGTGCCCACCCACAAAATAAAGAAGACATCCACGCCAGCCACGCCCTTTTAA
AAGCCCTAAAGAGCCTACACGCCACCCTGCCGCAAAAGAGCTTTAATCTGCAAGATCTCAAAGAAGCCATCACCAACGCC
CCTAATTTGCACCTAAGCCTTGAGTCTTACCTGCAAAACCCCCTCTTCAATGCCCTAGAAGACAGCCTAGAGTTTGACAC
TCCGCTTGCTGCCATAAACATGGATGCGATCAGTGCCAACCCTAAAGATTTGGGGCTTTTGGCGTATTACATTTTTTATA
AGATTTTACACCGTGCCCTAGAAAAACAAGAAGGCTTTTTGCTTTTTGTGGACGAGTTTAAAAGCTATGCACAAAATGAA
ACCCTAAACACCCACATCAACACCTTAATCACGCAAGCTAGAAAGGCGAATGGGGTCGTGGTGCTCGCCTTGCAAGATAC
AAACCAGCTTGCTAGCATTCCCGAGGCGGCAAGTTTCGTTAAAAACATGGGAACTTTGATTTTTTATCCCCAAAAGCACA
TAGACAGCACCTTACTTAGCAAGGATTTAGGCATCCAGCTAAGCTACATGGAAGCGCACTTTTTAGAAAACACCCCCCTA
ACCGCCAAGCAAGTTTTGGTGAAAAACATGGCAGAGGGCAGCTCAAACATCATCCATGTAGACTTACAAGACTTAGGAAC
GCATTTACGCATTTTCAACTCCAACGCCGCCCATGTCAAACGGCTGCAAGCCCTCATGCAGGCTTACCCTGAGACTTGGC
GGGAAGTCTTGTTGCAAGAGGGCTAA

Domains

Predicted by InterproScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (172-369)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	50.192	100	0.502