Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   K6J72_RS02995 Genome accession   NZ_AP024814
Coordinates   560871..563216 (+) Length   781 a.a.
NCBI ID   WP_221280519.1    Uniprot ID   -
Organism   Helicobacter sp. NHP19-003     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 555871..568216
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J72_RS02985 (NHP190003_06050) murJ 557039..558487 (-) 1449 WP_221280514.1 murein biosynthesis integral membrane protein MurJ -
  K6J72_RS02990 (NHP190003_06060) - 558796..560862 (+) 2067 WP_221280516.1 polysaccharide lyase family 8 super-sandwich domain-containing protein -
  K6J72_RS02995 (NHP190003_06070) comB4 560871..563216 (+) 2346 WP_221280519.1 transporter Machinery gene
  K6J72_RS03000 (NHP190003_06080) pseB 563255..564244 (+) 990 WP_221280523.1 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) -
  K6J72_RS03005 (NHP190003_06090) coaBC 564234..565463 (+) 1230 WP_221280525.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -

Sequence

Protein


Download         Length: 781 a.a.        Molecular weight: 87774.88 Da        Isoelectric Point: 7.2877

>NTDB_id=88582 K6J72_RS02995 WP_221280519.1 560871..563216(+) (comB4) [Helicobacter sp. NHP19-003]
MKFGLEFWQNKALDFLLGALPKTHSMVEENNILGLYNERFLLTKSEQLVGLLNVKGLSANALLQEDLQTHFASKQNALEQ
LEGVVLRIHTKRAKIKLDPPKKPPNPQVQALLDLSQPKDLYENTYTLIFETAQSPLKDFLEQKKLELTTDHKTQQHLALL
LSENMAKMAHALHAFKPTPLSAKEALNFYATFINGEPTHLNPTLGFLEDSYIATNLHFKKDHYIQEHASYTTYHRILGVK
AYASKTLSSLALLSLLHQELECEVFLSLEPLNQQKALAFVQEKIRLSFARLVRQELQNYYEQIQAKHLNLQKVALNVFLK
APDLESLNAHTKAVLGALSNAHLVAVVETLGLRPAYFSMFPGRLHLNPRLRCQSAQALATLMLFEKPNCGFKSNPWGEQP
LSVFKNLDHSPYLFNFHNQESDPSPNSPRTNGHTMIIGATGAGKTTLMGFLMANALKYDKLNILALDRAYGLFSCVNYFG
GVYNFGDQFKINPLSLELSPSSQDFLHSFYAHLLNVPEKLQTPEDIQASHAILKALKSLYATLPPKSFGLQDFKEALTHA
PNLHLSLEPYLQNPLFNALEDSLEFNTPLAAINMDAISANPKDLGLLAYYIFYKILQRALEKQEGFLLFVDEFKSYATNE
TLNTHINTLITQARKANGVVVLALQDTNQLATIPDAASFVKNMGTLIFYPQKHLDSTQLSQDLGIQLSYMEAHFLENTPL
NAQQVLVKNMAEGSSNIVHVGLQDLGAHLRIFNSNAAHVKRLQALMQAHPHTWREVLLQEG

Nucleotide


Download         Length: 2346 bp        

>NTDB_id=88582 K6J72_RS02995 WP_221280519.1 560871..563216(+) (comB4) [Helicobacter sp. NHP19-003]
TTGAAATTTGGCCTGGAGTTTTGGCAAAACAAAGCCCTAGATTTTTTGCTAGGGGCTCTGCCAAAAACCCACTCCATGGT
GGAAGAAAACAACATTTTAGGGCTTTACAATGAACGCTTTTTGCTCACCAAGAGCGAACAGCTTGTGGGGCTACTCAATG
TCAAAGGCTTGAGCGCAAACGCCTTACTCCAAGAGGACTTGCAAACCCATTTTGCCAGCAAACAAAATGCCCTAGAGCAG
TTAGAGGGCGTGGTGTTGCGTATCCACACCAAGCGCGCCAAAATCAAGCTAGATCCCCCAAAAAAGCCCCCAAACCCCCA
AGTACAAGCCTTATTAGACTTATCCCAACCCAAAGACCTATACGAAAACACCTACACTTTGATTTTTGAAACCGCCCAAA
GCCCCCTAAAAGACTTCTTAGAGCAGAAAAAATTAGAGCTCACCACAGACCACAAAACACAGCAACACCTAGCCTTGCTT
TTAAGCGAGAACATGGCGAAAATGGCGCACGCCTTGCACGCTTTCAAGCCCACGCCCCTAAGTGCCAAAGAAGCCCTGAA
CTTTTACGCCACTTTCATCAATGGAGAGCCCACACACTTAAACCCCACGCTGGGTTTCTTAGAAGACAGTTACATCGCCA
CAAACCTACATTTTAAAAAAGATCACTATATCCAAGAACACGCTAGCTACACGACCTACCACCGCATTTTAGGGGTGAAA
GCATATGCCAGCAAAACCCTAAGCTCTTTGGCTTTGCTCTCTCTCTTGCACCAAGAATTAGAATGCGAAGTGTTTTTAAG
TCTTGAGCCCTTAAACCAGCAAAAAGCCCTAGCCTTCGTGCAAGAAAAAATCCGCCTAAGTTTTGCACGCCTTGTACGCC
AAGAATTGCAAAACTACTATGAACAAATCCAAGCCAAGCACTTGAATCTACAAAAGGTCGCCCTAAATGTCTTTTTAAAA
GCCCCTGATTTAGAGAGCCTAAACGCCCACACCAAAGCGGTGCTAGGCGCGCTCTCCAACGCCCATTTAGTGGCTGTGGT
GGAAACTTTGGGACTAAGACCTGCCTACTTTTCCATGTTTCCTGGGCGTTTGCATTTAAACCCCCGTTTGCGTTGCCAAA
GCGCACAAGCCCTAGCCACGCTCATGCTCTTTGAAAAGCCAAATTGTGGCTTTAAAAGCAACCCGTGGGGTGAGCAACCT
TTAAGCGTGTTTAAAAACCTAGACCACTCCCCCTATCTATTTAATTTCCACAACCAAGAGAGCGACCCAAGCCCAAACAG
CCCCCGCACCAACGGGCATACCATGATCATCGGGGCCACAGGGGCGGGCAAGACGACCTTAATGGGCTTTTTAATGGCAA
ATGCACTCAAATACGACAAACTGAATATCCTAGCTCTCGATCGCGCCTATGGGCTGTTTTCGTGTGTCAATTACTTCGGA
GGGGTGTATAACTTCGGGGATCAGTTTAAAATTAACCCTCTATCTTTAGAATTAAGCCCCAGCAGCCAAGACTTTTTACA
CAGCTTTTATGCCCACCTGCTCAATGTCCCAGAAAAACTCCAAACCCCAGAAGACATACAGGCCAGCCACGCCATTTTAA
AAGCTCTAAAAAGTTTATATGCCACTTTGCCCCCTAAAAGCTTTGGTTTGCAAGATTTTAAAGAAGCCCTGACACATGCC
CCTAACTTGCACCTAAGCCTTGAACCTTATTTACAAAACCCCTTGTTTAACGCCCTAGAAGACAGCCTAGAGTTCAACAC
CCCCCTTGCCGCCATCAACATGGATGCCATCAGCGCAAACCCCAAGGACTTAGGGCTCTTGGCGTACTACATTTTCTACA
AAATTTTGCAGCGCGCCCTTGAGAAGCAAGAGGGCTTTTTGCTCTTTGTGGATGAGTTTAAAAGCTACGCCACTAACGAA
ACCCTAAACACCCACATCAACACCTTAATCACCCAGGCTAGAAAGGCCAATGGAGTGGTGGTCTTAGCCTTGCAAGACAC
TAACCAGCTGGCTACAATCCCCGATGCCGCCAGCTTCGTCAAAAACATGGGGACTTTGATTTTCTACCCCCAAAAGCACC
TAGACAGCACGCAACTTAGCCAAGATTTAGGGATACAGCTAAGTTATATGGAGGCGCATTTTTTAGAAAACACCCCCTTA
AACGCACAACAAGTCTTGGTCAAAAACATGGCGGAGGGCAGTTCTAACATCGTCCATGTGGGTTTGCAAGACTTAGGGGC
GCATTTACGCATCTTTAACTCCAATGCCGCCCATGTCAAACGCTTGCAAGCTCTCATGCAAGCGCATCCGCATACATGGC
GGGAAGTCTTGTTGCAAGAGGGCTAA

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(175-369)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

49.425

100

0.496

Multiple sequence alignment