Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   RJW53_RS00875 Genome accession   NZ_CP134488
Coordinates   136586..137539 (+) Length   317 a.a.
NCBI ID   WP_074389250.1    Uniprot ID   A0AAP6A670
Organism   Streptococcus suis strain NLS50     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 127257..137539 136586..137539 within 0


Gene organization within MGE regions


Location: 127257..137539
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW53_RS00815 (RJW53_00815) - 127257..127682 (-) 426 WP_226319165.1 ArpU family phage packaging/lysis transcriptional regulator -
  RJW53_RS00820 (RJW53_00820) - 128006..128581 (-) 576 WP_074392204.1 hypothetical protein -
  RJW53_RS00825 (RJW53_00825) - 128602..128775 (-) 174 WP_171840772.1 hypothetical protein -
  RJW53_RS00830 (RJW53_00830) - 129089..130525 (-) 1437 WP_257116214.1 phage/plasmid primase, P4 family -
  RJW53_RS00835 (RJW53_00835) - 130588..131466 (-) 879 WP_074389575.1 primase alpha helix C-terminal domain-containing protein -
  RJW53_RS00840 (RJW53_00840) - 131601..131885 (-) 285 WP_044766582.1 hypothetical protein -
  RJW53_RS00845 (RJW53_00845) - 131875..132213 (-) 339 WP_074390405.1 hypothetical protein -
  RJW53_RS00850 (RJW53_00850) - 132430..132873 (-) 444 WP_074390406.1 hypothetical protein -
  RJW53_RS00855 (RJW53_00855) - 133345..133971 (-) 627 WP_074390407.1 Rha family transcriptional regulator -
  RJW53_RS00860 (RJW53_00860) - 133988..134188 (-) 201 WP_015647585.1 helix-turn-helix transcriptional regulator -
  RJW53_RS00865 (RJW53_00865) - 134374..134883 (+) 510 WP_370695883.1 helix-turn-helix domain-containing protein -
  RJW53_RS00870 (RJW53_00870) - 135344..136489 (+) 1146 WP_074390408.1 site-specific integrase -
  RJW53_RS00875 (RJW53_00875) comYH 136586..137539 (+) 954 WP_074389250.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35764.89 Da        Isoelectric Point: 4.4133

>NTDB_id=880307 RJW53_RS00875 WP_074389250.1 136586..137539(+) (comYH) [Streptococcus suis strain NLS50]
MNFEKIEQAYDLLLENVQTIQNQLGTNIYDAMIEQNAAYVADQHEMDLVVNNNKTLKQLDLTKEEWRRAFQFLFIKANQT
EPMQYNHQFTPDSIGFILSFLVDQLVPTQKVTVLEIGSGTGNLAQTILNASQKELDYLGIEVDDLLIDLSASIADVMQAD
ISFAQGDAVRPQILKESQVILGDLPIGYYPDDQIASRYQVASPNEHTYAHHLLMEQSLKYLEKDGFAILLAPNDLLTSPQ
SDLLKGWLQEQANIVAMIALPPNLFGKAAMAKSIFVLQKKAARSLAPFVYPLQSLQEPEAIQKFMLNFKNWKQENAI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=880307 RJW53_RS00875 WP_074389250.1 136586..137539(+) (comYH) [Streptococcus suis strain NLS50]
ATGAATTTTGAAAAGATCGAACAGGCTTACGACCTGCTATTAGAAAACGTACAGACTATCCAAAACCAGCTAGGTACCAA
TATCTATGATGCCATGATTGAGCAAAATGCTGCTTACGTAGCTGATCAGCATGAGATGGACCTTGTTGTCAATAATAACA
AGACCTTGAAACAACTAGATTTAACCAAGGAAGAATGGCGTCGTGCCTTCCAATTCCTGTTCATCAAGGCCAATCAGACT
GAACCCATGCAGTACAATCACCAGTTCACACCAGACTCTATCGGATTTATCCTATCTTTTCTAGTAGACCAATTGGTGCC
GACTCAAAAGGTGACGGTTCTGGAAATTGGTTCGGGGACAGGCAATCTAGCTCAGACCATTCTCAACGCCAGCCAGAAAG
AATTGGATTACTTGGGGATCGAAGTGGACGACCTCTTGATTGATTTGTCGGCAAGTATTGCGGATGTCATGCAGGCAGAT
ATTTCTTTTGCTCAGGGAGATGCGGTACGTCCGCAGATTTTGAAGGAAAGTCAAGTAATTTTGGGAGATTTGCCTATTGG
CTACTATCCAGATGACCAGATTGCTAGCCGCTATCAGGTCGCCAGCCCAAATGAACATACCTACGCCCATCATTTGCTCA
TGGAACAATCCCTCAAATATCTGGAAAAAGATGGCTTTGCGATTTTGTTGGCTCCAAATGATTTATTGACTAGTCCGCAA
AGCGATTTGCTGAAAGGTTGGTTACAGGAGCAAGCCAATATTGTTGCCATGATTGCCCTGCCACCAAATCTCTTTGGGAA
GGCTGCTATGGCCAAGTCTATTTTTGTCTTGCAAAAGAAAGCTGCAAGATCGTTGGCGCCGTTTGTTTATCCCTTACAAA
GTCTTCAAGAACCAGAAGCTATTCAGAAGTTCATGCTCAATTTCAAAAATTGGAAGCAAGAGAATGCAATTTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(78-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

61.392

99.685

0.612
  comYH Streptococcus mutans UA159

61.076

99.685

0.609