Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX   Type   Regulator
Locus tag   RJW55_RS00435 Genome accession   NZ_CP134473
Coordinates   78726..79196 (+) Length   156 a.a.
NCBI ID   WP_043025097.1    Uniprot ID   A0A0Z8FNC4
Organism   Streptococcus suis strain TMW_SS028     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 73726..84196
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW55_RS00400 (RJW55_00400) cinA 73827..75008 (+) 1182 WP_043025095.1 competence/damage-inducible protein A Machinery gene
  RJW55_RS00405 (RJW55_00405) recA 75060..76211 (+) 1152 WP_004195473.1 recombinase RecA Machinery gene
  RJW55_RS00410 (RJW55_00410) spx 76371..76769 (+) 399 WP_004195475.1 transcriptional regulator Spx -
  RJW55_RS00415 (RJW55_00415) - 76876..77142 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  RJW55_RS00420 (RJW55_00420) ruvX 77142..77561 (+) 420 WP_061756370.1 Holliday junction resolvase RuvX -
  RJW55_RS00425 (RJW55_00425) - 77573..77890 (+) 318 WP_004195480.1 DUF1292 domain-containing protein -
  RJW55_RS00430 (RJW55_00430) - 78086..78631 (+) 546 Protein_65 nucleotidyltransferase family protein -
  RJW55_RS00435 (RJW55_00435) comX/sigX 78726..79196 (+) 471 WP_043025097.1 sigma-70 family RNA polymerase sigma factor Regulator
  RJW55_RS00440 (RJW55_00440) rpsJ 79462..79770 (+) 309 WP_002939332.1 30S ribosomal protein S10 -
  RJW55_RS00445 (RJW55_00445) rplC 79984..80610 (+) 627 WP_011921686.1 50S ribosomal protein L3 -
  RJW55_RS00450 (RJW55_00450) rplD 80635..81258 (+) 624 WP_004195490.1 50S ribosomal protein L4 -
  RJW55_RS00455 (RJW55_00455) - 81258..81557 (+) 300 WP_004195491.1 50S ribosomal protein L23 -
  RJW55_RS00460 (RJW55_00460) rplB 81575..82408 (+) 834 WP_002936663.1 50S ribosomal protein L2 -
  RJW55_RS00465 (RJW55_00465) rpsS 82659..82940 (+) 282 WP_000533766.1 30S ribosomal protein S19 -
  RJW55_RS00470 (RJW55_00470) rplV 82958..83302 (+) 345 WP_002936662.1 50S ribosomal protein L22 -
  RJW55_RS00475 (RJW55_00475) rpsC 83315..83968 (+) 654 WP_002936661.1 30S ribosomal protein S3 -

Sequence

Protein


Download         Length: 156 a.a.        Molecular weight: 19017.75 Da        Isoelectric Point: 9.2450

>NTDB_id=880139 RJW55_RS00435 WP_043025097.1 78726..79196(+) (comX/sigX) [Streptococcus suis strain TMW_SS028]
MKFEKVYASVKGIVNKARKEFYIKLWDREDWDQEGMMTLFELLEDQPWLADEQEQLYCYFKVKFRNRVKDRVRRQESQKR
KFDRMPHEDIHDLSHGIQSPGLVNDELLMLRGALRDYRKNLSDDQLVKYEKLISGQSFNGRKNMLRDLQEHLKDFR

Nucleotide


Download         Length: 471 bp        

>NTDB_id=880139 RJW55_RS00435 WP_043025097.1 78726..79196(+) (comX/sigX) [Streptococcus suis strain TMW_SS028]
ATGAAATTTGAAAAGGTCTATGCTAGCGTAAAAGGGATTGTCAACAAGGCTCGAAAAGAGTTTTATATTAAGCTCTGGGA
CAGGGAAGATTGGGATCAAGAGGGCATGATGACCTTATTTGAATTGTTGGAAGATCAACCGTGGTTAGCTGATGAGCAAG
AACAGTTGTATTGCTATTTTAAAGTGAAATTTAGAAATCGGGTCAAAGACCGCGTACGCAGACAAGAAAGTCAGAAGCGT
AAGTTTGATCGTATGCCGCATGAAGATATTCATGATTTATCTCACGGTATACAATCGCCAGGTTTAGTCAATGATGAGCT
GTTAATGTTGAGAGGGGCCTTGAGAGATTATCGTAAGAATCTCAGCGATGACCAGCTTGTGAAGTATGAAAAACTAATTA
GTGGTCAGAGTTTCAATGGTCGTAAGAATATGCTTAGGGATCTACAAGAACATTTAAAGGACTTTCGATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8FNC4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX Streptococcus suis D9

87.821

100

0.878
  comX/sigX Streptococcus suis isolate S10

87.179

100

0.872
  comX/sigX Streptococcus suis P1/7

87.179

100

0.872
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

49.677

99.359

0.494
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

49.677

99.359

0.494
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

43.791

98.077

0.429
  comX/sigX Streptococcus mutans UA159

43.506

98.718

0.429
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

42.038

100

0.423
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

43.137

98.077

0.423
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

42.484

98.077

0.417
  comX/comX1 Streptococcus pneumoniae Rx1

43.046

96.795

0.417
  comX/comX2 Streptococcus pneumoniae D39

43.046

96.795

0.417
  comX/comX1 Streptococcus pneumoniae D39

43.046

96.795

0.417
  comX/comX2 Streptococcus pneumoniae R6

43.046

96.795

0.417
  comX/comX1 Streptococcus pneumoniae R6

43.046

96.795

0.417
  comX/comX2 Streptococcus pneumoniae Rx1

43.046

96.795

0.417
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

41.83

98.077

0.41
  comX/comX1 Streptococcus pneumoniae TIGR4

42.384

96.795

0.41
  comX/comX2 Streptococcus pneumoniae TIGR4

42.384

96.795

0.41
  comX Streptococcus thermophilus LMG 18311

41.176

98.077

0.404
  comX Streptococcus thermophilus LMD-9

41.176

98.077

0.404
  comX Streptococcus salivarius SK126

40.523

98.077

0.397
  comX/sigX Streptococcus salivarius strain HSISS4

40.523

98.077

0.397
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

40.667

96.154

0.391
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

40.667

96.154

0.391
  comX Streptococcus sobrinus strain NIDR 6715-7

39.216

98.077

0.385
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40

96.154

0.385
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40

96.154

0.385
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40

96.154

0.385
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40

96.154

0.385