Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   RE424_RS10945 Genome accession   NZ_CP134047
Coordinates   2153819..2154535 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 21SAU_AGRO3     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2148819..2159535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RE424_RS10915 - 2149035..2149661 (+) 627 WP_103254130.1 nitroreductase family protein -
  RE424_RS10920 - 2150022..2150807 (+) 786 WP_000867941.1 carbon-nitrogen family hydrolase -
  RE424_RS14510 hld 2151406..2151486 (-) 81 WP_000046023.1 delta-hemolysin -
  RE424_RS10930 - 2151776..2152339 (+) 564 WP_001105705.1 accessory gene regulator AgrB -
  RE424_RS10935 agrD 2152343..2152483 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  RE424_RS10940 agrC 2152508..2153800 (+) 1293 WP_180991634.1 quorum-sensing sensor histidine kinase AgrC -
  RE424_RS10945 agrA 2153819..2154535 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  RE424_RS10950 - 2154607..2154716 (+) 110 Protein_2117 hypothetical protein -
  RE424_RS10955 - 2154904..2155863 (-) 960 WP_281340458.1 carbohydrate kinase -
  RE424_RS10960 - 2155860..2157344 (-) 1485 WP_000141427.1 sucrose-6-phosphate hydrolase -
  RE424_RS10965 - 2157493..2158443 (-) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=878346 RE424_RS10945 WP_000688492.1 2153819..2154535(+) (agrA) [Staphylococcus aureus strain 21SAU_AGRO3]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=878346 RE424_RS10945 WP_000688492.1 2153819..2154535(+) (agrA) [Staphylococcus aureus strain 21SAU_AGRO3]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1