Detailed information NTG0874591

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: RDV58_RS04160
• Genome accession: NZ_CP133475
• Coordinates: 790960..791841 (+)
• Length: 293 a.a.
• NCBI ID: WP_002262935.1
• Uniprot ID: Q8DT59
• Organism: Streptococcus mutans strain LMG 14558
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 785960..796841

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RDV58_RS04130 (RDV58_04130)	-	786145..787023 (+)	879	WP_002262941.1	F0F1 ATP synthase subunit gamma	-
RDV58_RS04135 (RDV58_04135)	atpD	787049..788455 (+)	1407	WP_002264827.1	F0F1 ATP synthase subunit beta	-
RDV58_RS04140 (RDV58_04140)	-	788469..788885 (+)	417	WP_002262939.1	F0F1 ATP synthase subunit epsilon	-
RDV58_RS04145 (RDV58_04145)	-	789157..789390 (+)	234	WP_002285829.1	DUF1146 family protein	-
RDV58_RS04150 (RDV58_04150)	murA	789456..790727 (+)	1272	WP_002262937.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
RDV58_RS04155 (RDV58_04155)	-	790730..790918 (+)	189	WP_002279970.1	DNA-directed RNA polymerase subunit beta	-
RDV58_RS04160 (RDV58_04160)	endA	790960..791841 (+)	882	WP_002262935.1	DNA/RNA non-specific endonuclease	Machinery gene
RDV58_RS04165 (RDV58_04165)	-	791909..792559 (-)	651	WP_002279971.1	amino acid ABC transporter permease	-
RDV58_RS04170 (RDV58_04170)	-	792574..793278 (-)	705	WP_002264823.1	amino acid ABC transporter permease	-
RDV58_RS04175 (RDV58_04175)	-	793296..794108 (-)	813	WP_002262932.1	transporter substrate-binding domain-containing protein	-
RDV58_RS04180 (RDV58_04180)	-	794105..794887 (-)	783	WP_002262931.1	amino acid ABC transporter ATP-binding protein	-
RDV58_RS04185 (RDV58_04185)	vicR	795240..795947 (+)	708	WP_002262930.1	response regulator YycF	Regulator

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 32130.72 Da
• Isoelectric Point: 9.5337

>NTDB_id=874591 RDV58_RS04160 WP_002262935.1 790960..791841(+) (endA) [Streptococcus mutans strain LMG 14558]
MTRKTNKSQRKQQKLCLSLLAALSVFVCTYIATSDHIADSNPIKQAAQLLTGKNKDILSNGSMSHQATPSQELANTVMTD
AVKNALGRQIEWSGAGSFIINHNKTDLNADVASQPYASNQTKIVQGQTVPTVANALLSKATRQYRNRQETGNGRTNWQPA
GWHQLYDLPGDYDHAVDRGHLLAYALVGGLKRFDASTSNPQNVATQAAWANEANSSNSRGQNYYETLIRKALDSHKRVRY
RVTLIYDDNNDILASGSHLEAKSSDGSLEFNVFIPNVQSGLTFDYATGQVKAN

Nucleotide

• Length: 882 bp

>NTDB_id=874591 RDV58_RS04160 WP_002262935.1 790960..791841(+) (endA) [Streptococcus mutans strain LMG 14558]
ATGACTAGAAAAACGAACAAGTCTCAGCGAAAACAGCAAAAATTATGCTTATCTCTCCTTGCTGCTTTGAGCGTATTTGT
TTGTACTTATATTGCAACCAGTGATCATATTGCTGATAGTAACCCTATAAAGCAGGCTGCCCAATTATTGACAGGTAAAA
ACAAGGATATACTTTCAAATGGTTCAATGAGCCATCAAGCGACTCCCAGTCAAGAATTAGCCAATACTGTTATGACGGAT
GCAGTAAAAAATGCCTTGGGTAGACAAATTGAATGGAGTGGTGCAGGTTCTTTCATTATTAATCATAATAAAACTGACCT
TAACGCTGATGTTGCTAGCCAACCGTATGCTAGTAATCAGACCAAAATCGTTCAAGGACAGACAGTACCAACAGTAGCAA
ATGCTTTGTTAAGTAAGGCTACTCGTCAGTACCGAAACCGCCAAGAGACAGGAAATGGCAGGACAAATTGGCAGCCAGCA
GGCTGGCATCAGCTTTATGATTTGCCGGGTGACTATGATCACGCGGTTGATCGTGGACACTTATTGGCTTATGCTTTGGT
TGGTGGTTTGAAACGATTTGATGCTTCAACGAGTAATCCTCAAAATGTAGCAACACAAGCAGCTTGGGCTAATGAAGCCA
ATAGTTCAAACTCAAGGGGACAAAATTATTATGAAACACTGATTAGAAAAGCTTTGGATAGTCATAAGCGTGTTCGTTAT
CGTGTGACTCTTATCTATGATGACAACAATGATATCTTAGCCAGTGGCAGTCATCTAGAAGCCAAATCATCAGATGGCAG
TCTAGAGTTCAATGTCTTTATTCCTAATGTTCAAAGCGGTTTGACCTTTGATTATGCAACAGGACAAGTTAAGGCAAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (99-251)

3D structure

• AlphaFold DB: Q8DT59

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	64.103	79.863	0.512
endA	Streptococcus pneumoniae D39	64.103	79.863	0.512
endA	Streptococcus pneumoniae R6	64.103	79.863	0.512
endA	Streptococcus pneumoniae TIGR4	64.103	79.863	0.512