Detailed information NTG0087200

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: K6K02_RS08600
• Genome accession: NZ_AP024626
• Coordinates: 1655966..1656745 (+)
• Length: 259 a.a.
• NCBI ID: WP_003220850.1
• Uniprot ID: G4NSM6
• Organism: Bacillus subtilis strain BEST3125
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1650966..1661745

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6K02_RS08580 (BsBEST3125_16280)	trmFO	1651659..1652966 (+)	1308	WP_003244725.1	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	-
K6K02_RS08585 (BsBEST3125_16290)	xerC	1653034..1653948 (+)	915	WP_014479777.1	tyrosine recombinase XerC	-
K6K02_RS08590 (BsBEST3125_16300)	clpQ	1653961..1654506 (+)	546	WP_003238555.1	ATP-dependent protease subunit ClpQ	-
K6K02_RS08595 (BsBEST3125_16310)	hslU	1654523..1655926 (+)	1404	WP_014476801.1	HslU--HslV peptidase ATPase subunit	-
K6K02_RS08600 (BsBEST3125_16320)	codY	1655966..1656745 (+)	780	WP_003220850.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
K6K02_RS08605 (BsBEST3125_16330)	flgB	1657125..1657514 (+)	390	WP_003245656.1	flagellar basal body rod protein FlgB	-
K6K02_RS08610 (BsBEST3125_16340)	flgC	1657514..1657966 (+)	453	WP_003245521.1	flagellar basal body rod protein FlgC	-
K6K02_RS08615 (BsBEST3125_16350)	fliE	1657977..1658297 (+)	321	WP_003238544.1	flagellar hook-basal body complex protein FliE	-
K6K02_RS08620 (BsBEST3125_16360)	fliF	1658343..1659953 (+)	1611	WP_010886506.1	flagellar basal-body MS-ring/collar protein FliF	-
K6K02_RS08625 (BsBEST3125_16370)	fliG	1659966..1660982 (+)	1017	WP_003231981.1	flagellar motor switch protein FliG	-
K6K02_RS08630 (BsBEST3125_16380)	fliH	1660975..1661727 (+)	753	WP_003244804.1	flagellar assembly protein FliH	-

Sequence

Protein

• Length: 259 a.a.
• Molecular weight: 29013.22 Da
• Isoelectric Point: 4.6514

>NTDB_id=87200 K6K02_RS08600 WP_003220850.1 1655966..1656745(+) (codY) [Bacillus subtilis strain BEST3125]
MALLQKTRIINSMLQAAAGKPVNFKEMAETLRDVIDSNIFVVSRRGKLLGYSINQQIENDRMKKMLEDRQFPEEYTKNLF
NVPETSSNLDINSEYTAFPVENRDLFQAGLTTIVPIIGGGERLGTLILSRLQDQFNDDDLILAEYGATVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELDGNEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNNKFLIELENLKSH

Nucleotide

• Length: 780 bp

>NTDB_id=87200 K6K02_RS08600 WP_003220850.1 1655966..1656745(+) (codY) [Bacillus subtilis strain BEST3125]
ATGGCTTTATTACAAAAAACAAGAATTATTAACTCCATGCTGCAAGCTGCGGCAGGGAAACCGGTAAACTTCAAGGAAAT
GGCGGAGACGCTGCGGGATGTAATTGATTCCAATATTTTCGTTGTAAGCCGCAGAGGGAAACTCCTTGGGTATTCTATTA
ACCAGCAAATTGAAAATGATCGTATGAAAAAAATGCTTGAGGATCGTCAATTCCCTGAAGAATATACGAAAAATCTGTTT
AATGTCCCTGAAACATCTTCTAACTTGGATATTAATAGTGAATATACTGCTTTCCCTGTTGAGAACAGAGACCTGTTTCA
AGCTGGTTTAACAACAATTGTGCCGATCATCGGAGGCGGGGAAAGATTAGGAACACTTATTCTTTCGCGTTTACAAGATC
AATTCAATGACGATGACTTAATTCTAGCTGAATACGGCGCAACAGTTGTCGGAATGGAAATCCTAAGAGAAAAAGCAGAA
GAAATTGAAGAGGAAGCAAGAAGCAAAGCTGTCGTACAAATGGCTATCAGCTCGCTTTCTTACAGTGAGCTTGAAGCAAT
TGAGCACATTTTTGAGGAGCTTGACGGAAATGAAGGTCTTCTTGTTGCAAGTAAAATTGCTGACCGTGTCGGCATTACCC
GTTCTGTTATTGTGAACGCACTCAGAAAGCTGGAGAGCGCCGGTGTTATCGAGTCTAGATCATTAGGAATGAAAGGTACT
TATATCAAGGTACTAAACAACAAATTCCTAATTGAATTAGAAAATCTAAAATCTCATTAA

Domains

Predicted by InterproScan.

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

• CodY GAF-like domain (CodY) (3-178)

3D structure

• AlphaFold DB: G4NSM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	100	100	1
codY	Lactococcus lactis subsp. lactis strain DGCC12653	47.451	98.456	0.467