Detailed information NTG0870549

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: RA106_RS05445
• Genome accession: NZ_CP132900
• Coordinates: 1043642..1044523 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CICC 20372
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1038642..1049523

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RA106_RS05420 (RA106_05440)	vicR	1039346..1040053 (-)	708	WP_011681206.1	response regulator YycF	Regulator
RA106_RS05425 (RA106_05445)	-	1040580..1041347 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
RA106_RS05430 (RA106_05450)	-	1041359..1042192 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
RA106_RS05435 (RA106_05455)	-	1042210..1042908 (+)	699	WP_011681209.1	amino acid ABC transporter permease	-
RA106_RS05440 (RA106_05460)	-	1042920..1043570 (+)	651	WP_024704148.1	amino acid ABC transporter permease	-
RA106_RS05445 (RA106_05465)	endA	1043642..1044523 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
RA106_RS05450 (RA106_05470)	-	1044585..1044773 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
RA106_RS05455 (RA106_05475)	murA	1044775..1046046 (-)	1272	WP_024704149.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
RA106_RS05460 (RA106_05480)	-	1046116..1046352 (-)	237	WP_002946959.1	DUF1146 family protein	-
RA106_RS05465 (RA106_05485)	galE	1046541..1047554 (-)	1014	WP_014621668.1	UDP-glucose 4-epimerase GalE	-
RA106_RS05470 (RA106_05490)	-	1047569..1048003 (-)	435	WP_231107205.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=870549 RA106_RS05445 WP_011681210.1 1043642..1044523(-) (endA) [Streptococcus thermophilus strain CICC 20372]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=870549 RA106_RS05445 WP_011681210.1 1043642..1044523(-) (endA) [Streptococcus thermophilus strain CICC 20372]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594