Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   QZN16_RS00410 Genome accession   NZ_CP129876
Coordinates   64256..65158 (+) Length   300 a.a.
NCBI ID   WP_000912098.1    Uniprot ID   A0AAD2WWZ7
Organism   Streptococcus agalactiae strain NEM316     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 59256..70158
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QZN16_RS00385 purE 59431..59922 (+) 492 WP_001875905.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  QZN16_RS00390 purK 59909..60982 (+) 1074 WP_001048172.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  QZN16_RS00395 - 60992..61249 (+) 258 WP_000590468.1 hypothetical protein -
  QZN16_RS00400 - 61615..62718 (+) 1104 WP_001867169.1 DUF6287 domain-containing protein -
  QZN16_RS00405 purB 62804..64102 (+) 1299 WP_000893937.1 adenylosuccinate lyase -
  QZN16_RS00410 comR 64256..65158 (+) 903 WP_000912098.1 helix-turn-helix domain-containing protein Regulator
  QZN16_RS00415 ruvB 65447..66445 (+) 999 WP_000196633.1 Holliday junction branch migration DNA helicase RuvB -
  QZN16_RS00420 - 66597..67034 (+) 438 WP_000754817.1 low molecular weight protein-tyrosine-phosphatase -
  QZN16_RS00425 - 67041..67421 (+) 381 WP_000787702.1 membrane protein -
  QZN16_RS00430 - 67418..69196 (+) 1779 WP_001220911.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 300 a.a.        Molecular weight: 35606.08 Da        Isoelectric Point: 6.5030

>NTDB_id=856018 QZN16_RS00410 WP_000912098.1 64256..65158(+) (comR) [Streptococcus agalactiae strain NEM316]
MLKHFGSKVRNLRVTRNITREDFCGDETELSVRQLARIESGQSIPNLTKAHYIAKQLNVKLDILTGGESLELPKRYKELK
YKLLRTPTYGDANRLAVREAYFDEIYEVFYEELPEDERLIIDCMQSKLDVHFSVNDNFGITILHDYFDQIKKKKEYTTND
FVMIDLYLLCFSINYGMKSLYSLENYHFIMSKLLEQDNLLPEDNFQLNNVLLNHVELAFQFKQKKYVQQIIHRSNAIMTE
IHDFQKRPILSLIEWKYLLIIEKDRTKAETCFKQSILFAELIGDLYLKGKLIEEWNKDLT

Nucleotide


Download         Length: 903 bp        

>NTDB_id=856018 QZN16_RS00410 WP_000912098.1 64256..65158(+) (comR) [Streptococcus agalactiae strain NEM316]
ATGTTAAAACATTTTGGTAGTAAAGTAAGAAATTTGAGAGTAACTAGAAATATTACTCGCGAAGATTTTTGTGGTGATGA
AACTGAGTTATCTGTAAGACAATTAGCTAGGATTGAAAGTGGACAGTCAATTCCAAACTTGACTAAAGCTCACTACATAG
CTAAACAATTGAATGTAAAATTGGATATTTTAACAGGAGGAGAGAGCTTAGAATTACCTAAACGGTATAAAGAGTTGAAG
TACAAATTGTTGCGTACCCCGACTTACGGAGATGCTAATAGACTTGCAGTTAGAGAAGCATATTTTGATGAAATCTATGA
AGTATTTTATGAGGAGCTCCCAGAAGATGAAAGACTAATTATTGATTGTATGCAATCAAAATTAGATGTTCATTTTTCTG
TTAATGATAATTTTGGAATCACTATTTTACATGACTACTTTGATCAAATTAAGAAAAAAAAGGAATATACCACAAATGAT
TTTGTTATGATAGATTTATATTTACTTTGCTTTTCTATTAACTATGGAATGAAGAGCTTGTATTCTTTAGAGAACTATCA
TTTTATTATGTCAAAATTGTTAGAGCAAGATAATTTACTTCCTGAGGATAATTTTCAATTGAACAACGTTTTATTAAATC
ATGTCGAATTAGCTTTTCAATTTAAGCAGAAAAAATATGTACAGCAAATTATTCATAGAAGTAATGCTATTATGACAGAA
ATCCATGATTTTCAAAAAAGACCAATACTAAGCTTAATAGAGTGGAAATATTTATTAATTATTGAAAAAGATAGAACAAA
AGCAGAAACATGTTTTAAACAATCAATTCTATTTGCAGAGTTAATAGGTGATCTATATTTAAAAGGAAAATTAATAGAGG
AGTGGAATAAAGATTTAACATGA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-295)

Helix-turn-helix (HTH_3)

(10-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

59.375

96

0.57
  comR Streptococcus mutans UA159

52.174

99.667

0.52
  comR Streptococcus pyogenes MGAS8232

50.166

100

0.503
  comR Streptococcus pyogenes MGAS315

47.667

100

0.477
  comR Streptococcus suis P1/7

40.067

99

0.397
  comR Streptococcus suis 05ZYH33

40.067

99

0.397
  comR Streptococcus suis D9

36.184

100

0.367