Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   V6U66_RS02710 Genome accession   NZ_CP145864
Coordinates   508508..510451 (+) Length   647 a.a.
NCBI ID   WP_410534562.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS7     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 503508..515451
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U66_RS02675 (V6U66_02675) prx 504150..504335 (+) 186 WP_045772500.1 Paratox Regulator
  V6U66_RS02680 (V6U66_02680) - 504810..505250 (+) 441 WP_410534558.1 helix-turn-helix domain-containing protein -
  V6U66_RS02685 (V6U66_02690) - 505784..506281 (-) 498 WP_045772502.1 GNAT family N-acetyltransferase -
  V6U66_RS02690 (V6U66_02695) - 506312..506455 (-) 144 WP_158084825.1 hypothetical protein -
  V6U66_RS02695 (V6U66_02700) - 506582..507664 (+) 1083 WP_410534559.1 hypothetical protein -
  V6U66_RS02700 (V6U66_02705) - 507696..508094 (+) 399 WP_410534560.1 hypothetical protein -
  V6U66_RS02705 (V6U66_02710) - 508106..508507 (+) 402 WP_410534561.1 hypothetical protein -
  V6U66_RS02710 (V6U66_02715) clpE 508508..510451 (+) 1944 WP_410534562.1 AAA family ATPase Regulator
  V6U66_RS02715 (V6U66_02720) - 510525..510872 (+) 348 WP_073689792.1 hypothetical protein -
  V6U66_RS02720 (V6U66_02725) - 510893..511225 (+) 333 WP_410534563.1 hypothetical protein -
  V6U66_RS02725 (V6U66_02730) tnpA 511322..511795 (-) 474 WP_002891962.1 IS200/IS605 family transposase -
  V6U66_RS02730 (V6U66_02735) - 511920..512843 (+) 924 WP_410534564.1 hypothetical protein -
  V6U66_RS02735 (V6U66_02740) - 512847..515090 (+) 2244 WP_410534565.1 hypothetical protein -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 73577.57 Da        Isoelectric Point: 8.0807

>NTDB_id=853589 V6U66_RS02710 WP_410534562.1 508508..510451(+) (clpE) [Streptococcus salivarius strain KSS7]
MKERTNHNLSKTPYIDKYTTDLTEKIRPKRQDFVAWGRQDEIRQVFISLNRLEKNSPVLIGEAGVGKTAIVEGICADILN
KKAHVPTRFQGKQVKQLELSAIQGKEFDHTGKEVNIIAKMDGLIKEFMAHKDEFILFIDEVHTIMGTGVEGSALDVANSL
KPALSRGEIYLISATTADEFMIIERDPAMERRLQPVYVDELDKEASILVLKKRRPKYKRELDIEITADAIKAAVGLSIRY
ITDKMLPDKAIDIIDEASATANIDGKSEITLKDIASVIHRKKGIPMESLLRTSSTPVDFAEGMRVVVKGQDHVIRTIARL
MYKGIQGGQNKRRPLGTLLLLGTTGTGKTELAKQAAKQLFGSEEAMIRLDMSEYMTDNAVVRLIGNDERKGDLTEKIKKN
PYSLVLLDELEKAHPDVWALYLQMLDDGHLTDGRGRKINFKNTFIIATSNVGHKRIKDKYITSGQTFTEMNKTDYKEFMK
DMRDELIKIFKRPEFINRWKIEVTNILTKQTIDKIVYSKMAVHEGSWFKEHHILINYEDVMDGDQTIDGKKYFYEYLSSV
GVSPEDGARPLERTIDEVLTDEIFEQLYFLGRKPQDYFMVDVSLSGHAPGTFAYGNSGRKTVQDRRQTHISVKRIPPEEY
GNYLLTS

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=853589 V6U66_RS02710 WP_410534562.1 508508..510451(+) (clpE) [Streptococcus salivarius strain KSS7]
ATGAAGGAGAGGACTAACCATAATCTTAGTAAGACTCCTTATATTGACAAATACACAACAGACCTTACTGAGAAAATCAG
ACCCAAGCGTCAAGATTTTGTGGCTTGGGGTAGACAAGATGAAATCAGACAAGTCTTTATCTCACTGAATCGATTAGAAA
AAAACTCTCCTGTACTAATTGGTGAAGCTGGTGTAGGTAAAACAGCTATTGTAGAAGGAATTTGTGCGGATATTCTTAAC
AAGAAAGCCCACGTCCCAACACGTTTCCAAGGTAAGCAGGTTAAGCAACTAGAATTATCTGCTATCCAAGGGAAAGAATT
TGACCATACAGGTAAAGAGGTGAACATCATTGCCAAAATGGACGGATTGATTAAAGAGTTCATGGCTCATAAAGATGAGT
TTATCCTCTTTATTGATGAAGTGCATACCATTATGGGAACTGGGGTTGAGGGAAGTGCTCTTGACGTCGCTAATAGCTTG
AAACCAGCCTTATCTCGTGGGGAAATCTATCTTATTTCAGCCACCACAGCTGATGAGTTTATGATTATTGAACGAGATCC
TGCAATGGAACGACGTCTGCAACCAGTTTACGTTGATGAACTGGACAAAGAGGCGTCTATTTTGGTCTTGAAAAAACGTC
GACCAAAGTACAAACGAGAACTTGACATTGAGATTACAGCTGATGCCATTAAGGCAGCAGTAGGATTATCCATTCGTTAT
ATTACGGACAAAATGCTTCCAGATAAAGCTATTGATATTATTGATGAAGCTTCAGCGACTGCAAATATCGATGGGAAATC
AGAGATTACCTTAAAAGATATTGCGAGTGTCATTCACCGTAAAAAAGGTATTCCTATGGAAAGTCTACTACGCACGTCTT
CAACTCCAGTGGATTTTGCGGAAGGGATGCGTGTGGTTGTTAAGGGGCAAGACCATGTGATTCGAACTATAGCACGCCTT
ATGTATAAGGGAATCCAGGGAGGACAGAACAAACGAAGGCCTCTTGGAACTCTTCTTCTGCTTGGAACAACAGGTACAGG
TAAAACTGAATTGGCGAAACAAGCAGCAAAACAACTGTTTGGTAGTGAAGAAGCGATGATTCGGCTGGATATGTCAGAAT
ACATGACTGATAATGCTGTTGTTCGTCTTATAGGAAATGACGAGCGAAAAGGTGACTTAACGGAAAAAATTAAGAAGAAT
CCCTACTCGTTAGTACTATTGGACGAGTTAGAAAAGGCTCATCCAGATGTATGGGCTTTATATTTGCAAATGCTTGATGA
TGGGCATTTAACTGACGGACGTGGACGAAAAATCAATTTTAAGAATACGTTTATCATTGCAACATCAAACGTGGGGCATA
AGCGAATCAAAGATAAATATATCACCTCTGGTCAGACCTTTACAGAAATGAACAAGACTGACTATAAAGAGTTCATGAAG
GACATGAGAGACGAGTTAATCAAGATCTTTAAACGTCCTGAATTTATCAACCGTTGGAAAATTGAAGTGACTAATATCTT
GACGAAACAAACCATTGATAAGATTGTCTATTCAAAAATGGCTGTACATGAGGGCAGTTGGTTTAAAGAGCATCATATCC
TTATTAATTATGAGGATGTTATGGATGGTGACCAAACTATCGATGGCAAAAAATACTTCTATGAATATCTCAGTAGTGTC
GGTGTTAGCCCAGAAGATGGAGCAAGGCCTTTAGAGAGAACTATTGATGAAGTATTAACTGATGAAATCTTTGAGCAATT
GTATTTCCTTGGGCGAAAGCCACAAGATTACTTTATGGTTGATGTGTCTTTATCTGGACATGCACCAGGAACGTTTGCGT
ATGGTAACTCAGGTAGAAAGACAGTTCAAGATAGGCGTCAGACGCATATTAGTGTCAAACGGATACCTCCAGAGGAGTAT
GGTAACTATTTGCTTACGTCTTAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(203-282)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(550-588)

ATPase family associated with various cellular activities (AAA) (AAA)

(58-183)

AAA domain (Cdc48 subfamily) (AAA_2)

(333-500)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

37.931

98.609

0.374
  clpE Streptococcus pneumoniae TIGR4

37.559

98.764

0.371
  clpE Streptococcus pneumoniae Rx1

37.559

98.764

0.371
  clpE Streptococcus pneumoniae D39

37.559

98.764

0.371
  clpE Streptococcus pneumoniae R6

37.559

98.764

0.371
  clpC Lactococcus lactis subsp. cremoris KW2

37.224

97.991

0.365