Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   V4942_RS06545 Genome accession   NZ_CP144687
Coordinates   1236736..1238970 (-) Length   744 a.a.
NCBI ID   WP_011173682.1    Uniprot ID   Q72I50
Organism   Thermus thermophilus strain TTHB27_delta_cmr4     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1231736..1243970
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V4942_RS06525 (V4942_06525) - 1232848..1233930 (+) 1083 WP_011173678.1 GGDEF domain-containing protein -
  V4942_RS06530 (V4942_06530) metK 1234032..1235210 (-) 1179 WP_038038694.1 methionine adenosyltransferase -
  V4942_RS06535 (V4942_06535) murI 1235305..1236078 (+) 774 WP_011173680.1 glutamate racemase -
  V4942_RS06540 (V4942_06540) - 1236108..1236761 (+) 654 WP_011173681.1 TIGR00730 family Rossman fold protein -
  V4942_RS06545 (V4942_06545) mutS/mutS2 1236736..1238970 (-) 2235 WP_011173682.1 endonuclease MutS2 Machinery gene
  V4942_RS06550 (V4942_06550) - 1239062..1240774 (-) 1713 WP_011173683.1 glycoside hydrolase family 13 protein -
  V4942_RS06555 (V4942_06555) - 1240771..1241106 (-) 336 WP_011173684.1 DUF86 domain-containing protein -
  V4942_RS06560 (V4942_06560) - 1241103..1241390 (-) 288 WP_011173685.1 nucleotidyltransferase family protein -
  V4942_RS06565 (V4942_06565) - 1241395..1242714 (-) 1320 WP_011173686.1 sugar ABC transporter permease -

Sequence

Protein


Download         Length: 744 a.a.        Molecular weight: 82501.50 Da        Isoelectric Point: 6.9483

>NTDB_id=847400 V4942_RS06545 WP_011173682.1 1236736..1238970(-) (mutS/mutS2) [Thermus thermophilus strain TTHB27_delta_cmr4]
MRDVLEVLEFPRVRALLAERAKTPLGRELALALAPLPREEAEKRHELTGEALSYPYALPEAGALREAYGRALAGARLSGP
ELLKAAKALEEAMALKEELLPLKNALSQVAEGIGDHTPFLERVRKALDEEGAVKDEASPRLAQIRRELRPLRQQILDRLY
ALMDRHREAFQDRFVTLRRERYCVPVRAGMAQKVPGILLDESESGATLFIEPFSVVKLNNRLQALRLKEEEEVNRILRDL
SERLAKDEGVPKTLEALGLLDLVQAQAALARDLGLSRPAFGERYELYRAFHPLIPDAVRNSFALDEKNRILLISGPNMGG
KTALLKTLGLAVLMAQSGLFVAAEKALLAWPDRVYADIGDEQSLQENLSTFAGHLRRLKEMLEEATPTSLVLIDELGSGT
DPEEGAALSQAILEALLERGVKGMVTTHLSPLKAFAQGREGIQNASMRFDLEALRPTYELVLGVPGRSYALAIARRLALP
EEVLKRAEALLPEGGRLEALLERLEAERLALEAERERLRRELSQVERLRKALAEREARFEEERAERLKALEEEVRAELLK
VEAELKALKEKARNEGKRDALRELMALRERYAKKAPPPPPPPGLAPGVLVEVPSLGKRGRVVELRGEEVLVQVGPLRMSL
RPQEVKPLPEAEPGKPLLAKPRREVKEVDLRGLTVAEALLEVDQALEEARALGLSTLRLLHGKGTGALRQAIREALRRDK
RVESFADAPPGEGGHGVTVVALRP

Nucleotide


Download         Length: 2235 bp        

>NTDB_id=847400 V4942_RS06545 WP_011173682.1 1236736..1238970(-) (mutS/mutS2) [Thermus thermophilus strain TTHB27_delta_cmr4]
GTGCGGGACGTCCTCGAGGTCCTGGAGTTCCCCCGGGTCCGGGCCCTGCTGGCGGAGAGGGCCAAGACCCCCCTGGGCCG
GGAGCTTGCCCTGGCCCTCGCGCCCCTTCCCCGGGAAGAGGCGGAGAAGCGGCACGAGCTCACGGGGGAGGCCCTAAGCT
ACCCCTACGCCCTCCCCGAGGCGGGGGCCTTAAGGGAGGCCTACGGGAGGGCCCTCGCGGGGGCGAGGCTTTCCGGCCCC
GAGCTCCTAAAGGCGGCCAAGGCCCTGGAGGAGGCCATGGCCCTGAAGGAGGAGCTCCTTCCCCTGAAAAACGCCTTAAG
CCAGGTGGCGGAGGGCATCGGGGACCACACCCCCTTCCTGGAGCGGGTGAGGAAGGCCCTGGACGAGGAGGGGGCGGTGA
AGGACGAGGCGAGCCCGAGGCTTGCCCAGATCCGAAGGGAGCTTAGGCCCCTCCGCCAGCAGATCCTGGACCGCCTCTAC
GCCCTCATGGACCGCCACAGGGAGGCCTTCCAGGACCGCTTCGTCACCTTAAGGCGGGAGCGCTACTGCGTCCCCGTGAG
GGCGGGGATGGCCCAGAAGGTGCCGGGGATCCTCCTGGACGAGTCCGAGTCGGGGGCGACCCTCTTCATAGAGCCCTTCT
CCGTGGTCAAGCTCAACAACCGCCTCCAGGCCCTGAGGCTAAAGGAGGAGGAGGAGGTGAACCGCATCCTCCGGGACCTC
TCCGAGAGGCTCGCCAAGGACGAGGGGGTGCCGAAGACCCTGGAGGCCCTGGGCCTTTTGGACCTCGTCCAGGCCCAGGC
CGCCTTGGCCCGGGACCTGGGGCTTTCCCGCCCCGCTTTCGGGGAGCGGTACGAGCTCTACCGGGCCTTTCACCCCCTGA
TCCCGGACGCCGTGCGGAACTCCTTCGCCCTGGACGAGAAAAACCGCATCCTCCTCATCTCCGGTCCCAACATGGGGGGA
AAGACCGCCCTCCTCAAGACCCTGGGCCTCGCCGTCCTCATGGCCCAGTCCGGCCTCTTCGTGGCGGCGGAGAAGGCCCT
TTTGGCCTGGCCCGACCGGGTCTATGCCGACATCGGGGACGAGCAGTCCCTTCAGGAGAACCTCTCCACCTTCGCCGGGC
ACTTAAGGCGCCTCAAGGAGATGCTGGAGGAGGCCACTCCCACGAGCCTCGTCCTCATTGACGAGCTCGGAAGCGGCACC
GACCCCGAGGAGGGGGCGGCCCTTTCCCAGGCCATCCTGGAGGCCCTCCTGGAGAGGGGGGTCAAGGGGATGGTCACCAC
CCACCTCTCCCCCCTGAAGGCCTTCGCCCAGGGAAGGGAGGGGATCCAGAACGCCTCCATGCGCTTTGACCTCGAGGCCC
TCCGTCCCACCTACGAGCTCGTCCTCGGGGTGCCGGGGCGGAGTTACGCCTTGGCCATCGCGAGGAGGCTCGCCCTCCCT
GAGGAGGTCCTCAAGCGGGCCGAGGCCCTTCTGCCCGAGGGGGGGCGGCTGGAGGCCCTTCTGGAGAGGCTCGAGGCCGA
GCGCCTGGCCCTGGAGGCGGAGCGGGAGCGCCTGAGGCGGGAGCTTTCCCAGGTGGAGAGGCTGCGCAAGGCCTTGGCCG
AGCGGGAGGCCCGCTTTGAGGAGGAGCGGGCGGAAAGGCTCAAGGCCCTCGAGGAGGAGGTGCGGGCCGAGCTCCTCAAG
GTGGAGGCCGAGCTCAAGGCCCTCAAGGAGAAGGCCAGGAACGAGGGCAAGCGGGACGCCCTCCGGGAACTCATGGCCCT
CCGGGAGCGCTACGCCAAGAAGGCCCCGCCGCCCCCGCCTCCGCCGGGCCTCGCCCCCGGGGTCTTGGTGGAGGTGCCGT
CCTTGGGCAAACGGGGCCGGGTGGTGGAGCTCAGGGGGGAGGAGGTCCTGGTCCAGGTGGGCCCCCTGAGGATGAGCCTC
AGGCCCCAGGAGGTGAAGCCCCTTCCCGAGGCCGAACCGGGCAAGCCCCTCCTCGCCAAGCCCCGGCGGGAGGTGAAGGA
GGTGGACCTCCGGGGCCTCACGGTGGCCGAGGCCCTTCTGGAGGTGGACCAGGCCCTGGAGGAGGCGCGGGCCCTGGGCC
TTTCCACCCTCCGCCTCCTCCACGGCAAGGGGACGGGGGCCTTAAGGCAGGCCATCCGGGAGGCCCTTCGCCGGGACAAG
CGGGTGGAAAGCTTCGCCGACGCCCCGCCCGGCGAGGGGGGGCATGGGGTTACCGTGGTGGCGCTTCGGCCTTGA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(312-490)

Smr domain (Smr)

(668-743)

MutS2 and Smr-associated SH3 domain (MSSS)

(606-640)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q72I50

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

34.919

100

0.375