Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   VKP40_RS01965 Genome accession   NZ_CP142355
Coordinates   382436..383218 (+) Length   260 a.a.
NCBI ID   WP_002992569.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain A946     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 377436..388218
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP40_RS01945 (VKP40_01945) - 377774..378739 (-) 966 WP_002983258.1 asparaginase -
  VKP40_RS01950 (VKP40_01950) - 378811..380199 (+) 1389 WP_023610533.1 Cof-type HAD-IIB family hydrolase -
  VKP40_RS01955 (VKP40_01955) - 380322..380774 (-) 453 WP_002992571.1 universal stress protein -
  VKP40_RS01960 (VKP40_01960) - 381005..382219 (+) 1215 WP_010922605.1 pyridoxal phosphate-dependent aminotransferase -
  VKP40_RS01965 (VKP40_01965) codY 382436..383218 (+) 783 WP_002992569.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  VKP40_RS01970 (VKP40_01970) - 383365..383919 (+) 555 WP_002988559.1 cysteine hydrolase family protein -
  VKP40_RS01975 (VKP40_01975) - 384457..384681 (+) 225 WP_014635660.1 putative PEP-binding protein -
  VKP40_RS01980 (VKP40_01980) gatC 384913..385215 (+) 303 WP_012560907.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  VKP40_RS01985 (VKP40_01985) gatA 385215..386681 (+) 1467 WP_136293763.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  VKP40_RS01990 (VKP40_01990) gatB 386681..388120 (+) 1440 WP_002983292.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28634.75 Da        Isoelectric Point: 4.5065

>NTDB_id=840591 VKP40_RS01965 WP_002992569.1 382436..383218(+) (codY) [Streptococcus pyogenes strain A946]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDDEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=840591 VKP40_RS01965 WP_002992569.1 382436..383218(+) (codY) [Streptococcus pyogenes strain A946]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACGATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(3-182)

CodY helix-turn-helix domain (HTH_CodY)

(202-260)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.765

98.077

0.508