Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   VKP53_RS01885 Genome accession   NZ_CP142354
Coordinates   350715..353054 (+) Length   779 a.a.
NCBI ID   WP_136277505.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 6745-99     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 345715..358054
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP53_RS01865 (VKP53_01865) lepB 348047..348640 (-) 594 WP_002983074.1 signal peptidase I -
  VKP53_RS01870 (VKP53_01870) rnhC 348651..349553 (-) 903 WP_136019450.1 ribonuclease HIII -
  VKP53_RS01875 (VKP53_01875) - 349710..350018 (+) 309 WP_002993251.1 hypothetical protein -
  VKP53_RS01880 (VKP53_01880) - 350021..350566 (+) 546 WP_002983087.1 CvpA family protein -
  VKP53_RS01885 (VKP53_01885) mutS/mutS2 350715..353054 (+) 2340 WP_136277505.1 endonuclease MutS2 Machinery gene
  VKP53_RS01890 (VKP53_01890) - 353058..353558 (+) 501 WP_162292734.1 phosphatase PAP2 family protein -
  VKP53_RS01895 (VKP53_01895) trxA 353621..353953 (+) 333 WP_001932060.1 thioredoxin -
  VKP53_RS01900 (VKP53_01900) - 353999..354592 (-) 594 WP_326674929.1 helix-turn-helix transcriptional regulator -
  VKP53_RS01905 (VKP53_01905) mutY 354769..355923 (-) 1155 WP_168389419.1 A/G-specific adenine glycosylase -
  VKP53_RS01910 (VKP53_01910) - 356091..356384 (+) 294 WP_002983113.1 hypothetical protein -
  VKP53_RS01915 (VKP53_01915) rpsF 356557..356847 (+) 291 WP_002983117.1 30S ribosomal protein S6 -
  VKP53_RS01920 (VKP53_01920) ssb 356869..357360 (+) 492 WP_002983122.1 single-stranded DNA-binding protein Machinery gene
  VKP53_RS01925 (VKP53_01925) rpsR 357525..357764 (+) 240 WP_002983142.1 30S ribosomal protein S18 -

Sequence

Protein


Download         Length: 779 a.a.        Molecular weight: 87919.21 Da        Isoelectric Point: 6.5183

>NTDB_id=840489 VKP53_RS01885 WP_136277505.1 350715..353054(+) (mutS/mutS2) [Streptococcus pyogenes strain 6745-99]
MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLEL
SADLNIQELLAIKKVLQSSSDMIHFYSDLDNVSFQSLDRLFENLEQFLNLQGSFQAINDGGFLEHFASPELERIRRQLTN
SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTVYIEPRAVVTLNEEITQLRADER
HEEGRILHTFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISDDSTLALINVRHPLLSNPVANDLHFDHD
LTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEAD
RNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPG
RSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKE
LEKIYQEAKEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVT
SYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQKVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDY
FIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRHKHVKHFAYAPQNAGGSGATIVTLG

Nucleotide


Download         Length: 2340 bp        

>NTDB_id=840489 VKP53_RS01885 WP_136277505.1 350715..353054(+) (mutS/mutS2) [Streptococcus pyogenes strain 6745-99]
ATGAATAACAAGATTTTAGAGCAGTTAGAATTTAACAAAGTTAAGGAATTGCTATTACCTTATCTCAAGACAGAACAATC
CCAAGAAGAATTATTAGAGCTGGAGCCGATGACGGAGGCTCCTAAAATAGAAAAAAGTTTTAATGAAATTTCTGACATGG
AACAGATTTTTGTTGAACATCACTCATTTGGCATAGTCAGCCTAAGTTCAATCTCTGAGAGTTTAAAACGCTTAGAGCTT
TCAGCTGATCTTAATATTCAAGAACTTTTGGCTATCAAAAAAGTTTTACAGAGTTCTTCGGATATGATTCACTTTTATTC
TGATTTGGATAATGTTTCTTTCCAATCTTTGGATCGTTTGTTTGAAAATTTGGAACAATTCCTTAATCTGCAAGGGTCTT
TTCAAGCTATCAATGATGGTGGTTTTTTAGAACATTTTGCGAGTCCAGAATTAGAGCGTATCCGTCGTCAATTAACAAAT
AGTGAACGACGGGTTCGTCAGATTTTACAGGATATGCTTAAGGAAAAAGCAGAGCTTTTATCAGAGAATCTAATCGCTAG
TCGTAGTGGACGAAGTGTCCTACCAGTAAAAAATACTTATCGGAATCGTATTTCTGGTGTGGTTCATGACATCTCTTCTT
CAGGAAGTACTGTTTATATTGAGCCTCGTGCTGTAGTTACACTAAACGAAGAGATAACGCAGCTTAGAGCTGACGAACGC
CACGAAGAAGGTCGTATTTTACACACATTTTCAGACTTGTTAAGACCTCATGTCGCCACTATTAGAAATAATGCATGGAT
TCTTGGGCATCTTGATTTTGTAAGGGCTAAATATCTTTTTATGTCTGATAATAAGGCGACGATACCTAAGATCTCTGATG
ACAGCACGTTAGCATTAATCAATGTTCGTCATCCTCTGTTAAGTAATCCTGTGGCTAATGACTTACATTTTGATCACGAT
TTAACTGCAATTGTCATCACTGGTCCCAATACTGGTGGTAAGACGATTATGCTAAAAACACTCGGTTTAGCACAATTAAT
GGGACAGTCTGGCTTGCCAGTATTAGCGGATAAAGGTAGTAAAATTGCAGTATTTAACAATATCTTTGCAGATATTGGCG
ATGAGCAATCTATTGAACAAAGTCTATCAACTTTTTCTAGTCATATGACGCACATAGTCAGTATTTTAAACGAGGCTGAC
CGCAATAGTTTAGTTCTCTTTGATGAACTAGGAGCAGGAACGGATCCTCAAGAAGGTGCTAGTTTGGCTATGGCTATTTT
AGAACACCTTAGGTTAAGTCATATCAAAACGATGGCGACCACGCACTATCCAGAATTAAAAGCTTATGGGATTGAGACAA
ATTTTGTAGAGAATGCGAGCATGGAATTTGATGCCGAAACGCTTAGCCCCACGTATCGCTTTATGCAAGGAGTTCCTGGA
CGATCAAATGCATTTGAAATTGCTTCTCGCCTTGGTTTAGCTCCATTTATTGTTAAACAAGCTAAGCAGATGACAGATTC
TGACTCAGATGTTAACCGTATTATTGAACAGTTAGAGGCACAGACACTTGAGACACGTAGAAGACTGGATCATATTAAAG
AAGTTGAACAAGAAAATCTCAAATTCAATCGTGCGGTTAAGAAACTCTATAATGAATTTTCACATGAACGCGATAAAGAG
TTAGAAAAAATCTATCAAGAAGCTAAAGAAATTGTAGATATGGCTTTGAATGAGAGTGATACTATCTTAAAAAAACTCAA
TGATAAGAGCCAATTAAAACCTCACGAAATTATAGATGCTAAGGCACAAATAAAAAAATTAGCACCTCAAGTTGATTTAT
CAAAAAATAAAGTCTTAAATAAGGCTAAAAAAATCAAAGCAGCTCGTGCCCCTAGAATTGGTGATGATATTATAGTGACC
AGTTATGGACAGCGAGGTACCTTAACTAGTCAATTAAAAGATGGCCGTTGGGAAGCACAAGTGGGAATTATCAAAATGAC
ATTAACACAAGATGAATTTAGCCTCGTTAGAGTCCAAGAAGAACAGAAAGTCAAAAATAAACAGATTAATGTGGTTAAAA
AGGCTGATAGTTCTGGACCAAGAGCTCGACTTGACCTTAGAGGTAAAAGATACGAAGAAGCTATGCAAGAGTTAGATTAT
TTTATTGATCAAGCATTGCTTAACAATATGGGACAAGTTGATATCATTCATGGGATTGGTACAGGCGTTATTCGTGAGGG
AGTGACAAAATATCTTCGTCGTCATAAGCATGTTAAGCATTTTGCTTATGCCCCACAAAATGCAGGGGGATCTGGTGCCA
CAATTGTAACGTTAGGGTAA

Domains

Predicted by InterProScan.

Smr domain (Smr)

(704-778)

MutS domain V (MutS_V)

(324-505)

MutS2 and Smr-associated SH3 domain (MSSS)

(633-669)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

40.759

100

0.413