Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   VKP35_RS02050 Genome accession   NZ_CP142349
Coordinates   393976..394758 (+) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain 11RS100     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 388976..399758
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP35_RS02030 (VKP35_02030) - 389315..390280 (-) 966 WP_002983258.1 asparaginase -
  VKP35_RS02035 (VKP35_02035) - 390352..391740 (+) 1389 WP_002983261.1 Cof-type HAD-IIB family hydrolase -
  VKP35_RS02040 (VKP35_02040) - 391862..392314 (-) 453 WP_002983265.1 universal stress protein -
  VKP35_RS02045 (VKP35_02045) - 392545..393759 (+) 1215 WP_011528914.1 pyridoxal phosphate-dependent aminotransferase -
  VKP35_RS02050 (VKP35_02050) codY 393976..394758 (+) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  VKP35_RS02055 (VKP35_02055) - 394905..395459 (+) 555 WP_002983281.1 cysteine hydrolase family protein -
  VKP35_RS02060 (VKP35_02060) - 395973..396221 (+) 249 WP_027968852.1 putative PEP-binding protein -
  VKP35_RS02065 (VKP35_02065) gatC 396453..396755 (+) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  VKP35_RS02070 (VKP35_02070) gatA 396755..398221 (+) 1467 WP_002983290.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  VKP35_RS02075 (VKP35_02075) gatB 398221..399660 (+) 1440 WP_111713344.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=840018 VKP35_RS02050 WP_002983278.1 393976..394758(+) (codY) [Streptococcus pyogenes strain 11RS100]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=840018 VKP35_RS02050 WP_002983278.1 393976..394758(+) (codY) [Streptococcus pyogenes strain 11RS100]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAATTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTAACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504