Detailed information NTG0839889

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: VRA41_RS07575
• Genome accession: NZ_CP142105
• Coordinates: 1448883..1449668 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain SCB0351
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1443883..1454668

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VRA41_RS07540 (VRA41_07540)	gatC	1443949..1444251 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
VRA41_RS07545 (VRA41_07545)	-	1444391..1444645 (-)	255	WP_011226449.1	glycosyl transferase	-
VRA41_RS07550 (VRA41_07550)	-	1444658..1444855 (-)	198	WP_231108739.1	glycosyltransferase	-
VRA41_RS07555 (VRA41_07555)	-	1445183..1446624 (-)	1442	Protein_1445	6-phospho-beta-glucosidase	-
VRA41_RS07560 (VRA41_07560)	msrA	1446777..1447286 (-)	510	WP_041827089.1	peptide-methionine (S)-S-oxide reductase MsrA	-
VRA41_RS07565 (VRA41_07565)	-	1447298..1448146 (-)	849	WP_065429507.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
VRA41_RS07570 (VRA41_07570)	-	1448269..1448820 (-)	552	WP_002946999.1	cysteine hydrolase family protein	-
VRA41_RS07575 (VRA41_07575)	codY	1448883..1449668 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
VRA41_RS07580 (VRA41_07580)	-	1449928..1451142 (-)	1215	WP_011226456.1	pyridoxal phosphate-dependent aminotransferase	-
VRA41_RS07585 (VRA41_07585)	-	1451497..1451949 (+)	453	WP_002946987.1	universal stress protein	-
VRA41_RS07590 (VRA41_07590)	-	1452129..1452700 (+)	572	Protein_1452	IS30 family transposase	-
VRA41_RS07595 (VRA41_07595)	-	1452916..1453386 (-)	471	WP_011227497.1	membrane protein	-
VRA41_RS07600 (VRA41_07600)	pflA	1453592..1454392 (-)	801	WP_002946980.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=839889 VRA41_RS07575 WP_002951720.1 1448883..1449668(-) (codY) [Streptococcus thermophilus strain SCB0351]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=839889 VRA41_RS07575 WP_002951720.1 1448883..1449668(-) (codY) [Streptococcus thermophilus strain SCB0351]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTAGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTATCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGTACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502