Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   VF946_RS01195 Genome accession   NZ_CP141824
Coordinates   228688..231021 (+) Length   777 a.a.
NCBI ID   WP_024405878.1    Uniprot ID   -
Organism   Streptococcus suis strain HB18     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 223688..236021
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VF946_RS01175 treP 224339..226333 (-) 1995 WP_074389394.1 PTS system trehalose-specific EIIBC component -
  VF946_RS01180 treR 226566..227279 (+) 714 WP_024393394.1 trehalose operon repressor Regulator
  VF946_RS01185 - 227337..227648 (+) 312 WP_002935948.1 hypothetical protein -
  VF946_RS01190 - 227645..228193 (+) 549 WP_002935945.1 CvpA family protein -
  VF946_RS01195 mutS/mutS2 228688..231021 (+) 2334 WP_024405878.1 endonuclease MutS2 Machinery gene
  VF946_RS01200 - 231045..231757 (+) 713 Protein_203 GNAT family N-acetyltransferase -
  VF946_RS01205 trxA 232122..232436 (+) 315 WP_024386049.1 thioredoxin -
  VF946_RS11660 - 232536..232586 (-) 51 WP_353735889.1 hypothetical protein -
  VF946_RS01210 - 232576..234105 (+) 1530 WP_074389711.1 AMP-binding protein -
  VF946_RS01215 msrB 234145..235083 (+) 939 WP_074389391.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 777 a.a.        Molecular weight: 87597.32 Da        Isoelectric Point: 6.5651

>NTDB_id=838159 VF946_RS01195 WP_024405878.1 228688..231021(+) (mutS/mutS2) [Streptococcus suis strain HB18]
MNNKIIETLEFHKVRQKIEPYLLTEQGFEELRQLEPMVEVHRIQQAFDELTDIAQIFVENPYFSLAATSDIGPAMRRLEL
DTDLNIAELLAVKKVLEVSKSLLDFYGNLENVSLSQLDKLFEKIELFPHLQGSLQSINDAGFVEDFASEKLARIRRKIRE
AEDQVRQVMQDILKTKGDMLSDSILASRNGRNVLPVKNTYRNKIAGVVHDISASGSTVYIEPRAVVTLNEEISHLRAEER
HELNRILQELSDMLRPHSGVIRNNAWLIGHIDFVRAKHLFARDHQAVVPKLSEKQDIALLNVRHPLIAKPVPNDLYFGSQ
LTAIVITGPNTGGKTIMLKTLGLTHLMAQSGLPILADEGSRVAIFKEIFADIGDEQSIEQSLSTFSSHMTHTVEILRAAD
QDSLILFDELGAGTDPQEGASLAMAILDDLRLRGIKTMATTHYPELKAYGIETSGIENASMEFDSNSLRPTYKFMQGVPG
RSNAFEIARRLGLSDIIIQSAQSWTDTDSDVNRIIEKLESQTVESRQRLDKIRDVEQENYKMNRALRKLYDELNRERENE
LNKARLEAKEIVDMALAESEDILKNLHAAASLKPHQIIEAKAELKKLAPEVVDLSKNKVLKKAKIQREAKVGDDIIVTAY
GQRGTLTNQLKDGRWEAQVGLIKMTLAKDEFELVKAEKAEQPKKRQVHTVKRANVRGPKARLDLRGKRYEEAMMELDEFI
DQALLNNLAQVDIVHGIGTGVIREGVTKYLRRNKQVKEFGYAPQNAGGSGCTIVMFK

Nucleotide


Download         Length: 2334 bp        

>NTDB_id=838159 VF946_RS01195 WP_024405878.1 228688..231021(+) (mutS/mutS2) [Streptococcus suis strain HB18]
ATGAATAATAAAATTATTGAAACCCTTGAATTTCACAAGGTAAGACAAAAAATTGAGCCCTATCTCTTGACGGAACAGGG
CTTTGAAGAATTACGACAGTTGGAGCCCATGGTGGAAGTCCATCGTATCCAACAGGCCTTCGACGAGTTGACAGACATAG
CGCAGATTTTTGTGGAAAATCCCTATTTCAGTCTGGCTGCTACTAGTGACATCGGTCCAGCCATGCGTCGTTTGGAATTG
GATACAGACCTCAATATCGCTGAATTATTAGCTGTTAAAAAGGTCTTGGAAGTTTCTAAATCTCTCTTGGATTTTTATGG
AAATCTGGAAAATGTCAGTCTTAGCCAGTTGGATAAACTCTTTGAGAAGATTGAGCTTTTTCCACATTTACAGGGCTCCC
TCCAGTCCATCAATGATGCTGGTTTTGTAGAGGATTTTGCCTCAGAAAAGCTGGCTCGTATTCGAAGAAAAATCCGTGAA
GCTGAAGATCAAGTTCGTCAGGTCATGCAGGATATTTTGAAGACCAAGGGCGACATGCTGTCCGATAGCATTTTGGCAAG
CCGTAATGGACGCAATGTCCTTCCTGTTAAAAATACCTATCGCAATAAGATTGCAGGGGTTGTCCATGACATTTCAGCTT
CGGGTTCGACCGTTTATATTGAGCCGCGGGCAGTGGTGACCTTGAACGAAGAAATCAGTCACCTACGTGCAGAAGAACGC
CATGAGCTCAACCGTATCTTGCAGGAATTGTCGGATATGCTCCGTCCGCATAGTGGCGTGATTCGTAACAATGCCTGGCT
TATCGGACATATTGATTTCGTCCGTGCTAAGCATCTCTTTGCGCGTGATCATCAAGCAGTTGTACCCAAACTATCTGAGA
AGCAGGATATTGCCCTTCTCAACGTTCGGCATCCGCTCATTGCTAAGCCTGTACCAAATGACCTTTATTTCGGTAGTCAG
TTGACGGCTATCGTGATAACAGGTCCCAACACAGGTGGTAAGACCATCATGCTTAAGACCTTGGGATTGACCCATCTGAT
GGCCCAGTCTGGTTTGCCTATCTTGGCTGATGAGGGCAGTCGGGTAGCTATCTTCAAAGAAATTTTTGCGGATATTGGGG
ATGAACAGTCGATTGAGCAGAGTTTATCAACCTTCTCCAGTCACATGACCCACACGGTGGAAATTTTAAGAGCAGCTGAT
CAAGATTCTCTCATTCTATTTGACGAGTTGGGAGCTGGGACAGATCCGCAGGAGGGTGCGTCGCTGGCAATGGCTATTTT
GGATGACCTTCGTCTGCGGGGGATCAAGACCATGGCGACCACCCACTACCCTGAGCTTAAGGCCTACGGGATAGAAACCT
CTGGTATTGAAAATGCCAGCATGGAGTTTGATAGCAATAGCCTGCGTCCGACCTATAAGTTTATGCAGGGTGTTCCTGGT
CGCTCCAATGCCTTTGAAATTGCCCGCCGTCTGGGTCTATCTGACATCATTATCCAGTCGGCTCAGTCTTGGACCGATAC
AGATAGCGATGTGAACCGCATTATCGAGAAATTGGAAAGTCAGACGGTTGAAAGTCGTCAGCGTCTGGATAAGATTCGTG
ATGTAGAGCAAGAAAATTACAAGATGAACCGAGCCCTCCGCAAGCTCTATGACGAGCTCAATCGTGAGAGAGAAAATGAG
CTCAACAAGGCACGCTTGGAGGCCAAGGAAATTGTAGATATGGCATTGGCAGAAAGCGAGGATATTCTCAAAAATCTCCA
TGCTGCAGCTAGTCTTAAGCCCCACCAGATTATTGAAGCCAAGGCAGAGCTGAAAAAGTTGGCGCCTGAAGTGGTGGATC
TGTCTAAAAACAAGGTTCTGAAGAAAGCTAAAATTCAGAGGGAAGCCAAGGTGGGTGATGACATTATCGTTACAGCTTAT
GGACAACGTGGGACCTTGACCAATCAGCTCAAGGACGGGCGTTGGGAAGCTCAGGTTGGCTTGATTAAGATGACCTTGGC
CAAAGATGAGTTTGAGTTAGTCAAGGCGGAAAAGGCAGAGCAGCCTAAGAAACGCCAGGTTCACACAGTCAAACGTGCCA
ATGTACGAGGACCAAAAGCCCGCTTAGATCTCCGTGGCAAACGCTACGAAGAGGCTATGATGGAACTGGATGAATTTATC
GACCAGGCCCTTCTCAATAACCTAGCACAAGTAGACATTGTCCACGGTATAGGTACAGGTGTCATCCGAGAAGGGGTGAC
CAAGTACCTACGCCGAAACAAGCAGGTCAAGGAGTTCGGCTATGCCCCACAAAATGCAGGTGGATCAGGCTGTACTATTG
TGATGTTTAAGTAG

Domains

Predicted by InterProScan.

MutS2 and Smr-associated SH3 domain (MSSS)

(631-670)

MutS domain V (MutS_V)

(324-504)

Smr domain (Smr)

(702-777)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.773

100

0.405