Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   U0449_RS03305 Genome accession   NZ_CP139862
Coordinates   652428..654764 (-) Length   778 a.a.
NCBI ID   WP_322397969.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 05H0020-2     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 647428..659764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0449_RS03285 serS 647689..648963 (+) 1275 WP_000884252.1 serine--tRNA ligase -
  U0449_RS03290 - 648988..649887 (-) 900 WP_000735969.1 TDT family transporter -
  U0449_RS03295 - 649997..650545 (-) 549 WP_000206761.1 carboxymuconolactone decarboxylase family protein -
  U0449_RS03300 - 650763..652085 (-) 1323 WP_322397967.1 sodium:alanine symporter family protein -
  U0449_RS03305 mutS/mutS2 652428..654764 (-) 2337 WP_322397969.1 endonuclease MutS2 Machinery gene
  U0449_RS03310 - 654868..655416 (-) 549 WP_000622944.1 CvpA family protein -
  U0449_RS03315 zapA 655413..655715 (-) 303 WP_000002019.1 cell division protein ZapA -
  U0449_RS03320 rnhC 655802..656683 (+) 882 WP_000146855.1 ribonuclease HIII -
  U0449_RS03325 lepB 656687..657301 (+) 615 WP_001083986.1 signal peptidase I -
  U0449_RS03330 - 657381..657503 (+) 123 WP_001815645.1 hypothetical protein -

Sequence

Protein


Download         Length: 778 a.a.        Molecular weight: 87625.63 Da        Isoelectric Point: 6.8352

>NTDB_id=832291 U0449_RS03305 WP_322397969.1 652428..654764(-) (mutS/mutS2) [Streptococcus pneumoniae strain 05H0020-2]
MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIKQAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEM
GADLNIEEFLLLKRVLLASRELQSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTVYIEPREVVKLSEEIASLRADER
YEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRAKVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQD
LTAIVITGPNTGGKTIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNIVDILGKVN
QHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYGIETAFVQNASMEFDTATLRPTYRFMQGVPG
RSNAFEIAKRLGLSEVIVGDASQQIDQDNDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRVLKKLYNELNREKETE
LNKAREQAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAKKKRAPKVGDDIVVLSY
GQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKLVKKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFI
DQALLNNMAQVDIIHGIGTGVIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG

Nucleotide


Download         Length: 2337 bp        

>NTDB_id=832291 U0449_RS03305 WP_322397969.1 652428..654764(-) (mutS/mutS2) [Streptococcus pneumoniae strain 05H0020-2]
ATGAATAAGAAAATATTAGAAACATTAGAGTTCGATAAGGTCAAGGCCTTGTTTGAGCCTCATTTGTTGACCGAGCAGGG
CTTGGAGCAATTGAGACAACTGGCTCCGACTGCCAAAGCAGATAAAATCAAACAGGCTTTTGCTGAGATGAAGGAAATGC
AGGCTCTTTTCGTCGAGCAACCGCATTTTACTATTCTCTCAACTAAGGAAATTGCAGGAGTCTGCAAGAGGTTGGAGATG
GGAGCGGATCTCAATATCGAGGAGTTCCTACTCTTGAAACGCGTGCTTCTTGCCAGCCGAGAACTTCAAAGTTTTTACGC
CAATCTGGAAAATGTCAGCTTGGAAGAATTAGCCCTTTGGTTTGAGAAATTACATGATTTTCCGCAATTACAAGGAAATC
TTCAGGCCTTTAATGATGCGGGTTTCATTGAAAATTTTGCCAGTGAAGAATTGGCGCGAATCCGTCGAAAAATACATGAT
AGCGAGAGTCAGGTACGCGATGTTTTACAAGACTTGCTCAAGCAAAAAGCGCAGATGTTGACGGAAGGAATTGTTGCTAG
CAGAAATGGCCGTCAGGTTTTACCAGTCAAAAACACCTACCGCAATAAGATTGCAGGTGTCGTTCATGATATTTCTGCTA
GTGGAAACACCGTCTATATCGAACCACGTGAGGTAGTCAAACTGAGCGAAGAAATTGCTAGTCTGCGAGCAGATGAGCGC
TATGAAATGCTTCGCATTCTCCAAGAAATTTCTGAGCGTGTCCGCCCTCATGCGGCTGAGATTGCTAATGACGCTTGGAT
TATCGGTCATCTGGACTTGATTCGTGCCAAGGTTCGATTTATTCAAGAAAGACAAGCAGTCGTGCCTCAGCTGTCAGAAA
ATCAAGAGATTCAACTGCTCCATGTCTGCCATCCTTTGGTCAAAAATGCCGTCGCAAATGATGTCTATTTTGGTCAAGAT
TTAACAGCTATTGTCATTACAGGTCCCAATACAGGTGGGAAGACCATCATGCTCAAAACTCTGGGCTTGACACAGGTCAT
GGCCCAGTCAGGATTGCCGATTTTAGCAGACAAGGGAAGTCGTGTTGGTATTTTTGAAGAAATTTTTGCTGATATTGGAG
ATGAGCAGTCTATTGAGCAGAGCTTGTCTACCTTCTCTAGCCATATGACCAATATCGTGGATATTCTTGGCAAGGTCAAC
CAACATTCACTCTTACTTTTGGATGAGTTGGGGGCTGGTACTGATCCCCAAGAGGGAGCAGCCCTTGCCATGGCTATTCT
GGAGGACCTTCGCCTGCGTCAAATCAAGACCATGGCGACGACCCACTATCCAGAACTCAAGGCCTACGGTATTGAGACAG
CCTTTGTGCAAAATGCCAGTATGGAGTTTGATACTGCAACTCTTCGCCCGACCTATCGCTTTATGCAGGGTGTTCCTGGC
CGAAGTAATGCCTTTGAAATTGCCAAACGTCTAGGCCTATCTGAAGTTATCGTAGGAGATGCCAGTCAGCAGATCGATCA
GGACAATGACGTCAATCGTATCATTGAGCAACTAGAAGAGCAGACGCTGGAAAGCCGCAAACGCTTGGACAATATCCGTG
AGGTGGAGCAAGAAAATCTCAAGATGAACCGTGTGCTAAAAAAACTCTACAACGAGCTTAATCGTGAAAAGGAAACCGAG
CTTAACAAGGCGCGTGAACAGGCTGCTGAGATTGTGGATATGGCCCTAAGTGAAAGTGACCAGATTCTCAAAAATCTCCA
CAGTAAATCCCAACTCAAGCCCCACGAAATCATTGAAGCCAAAGCCAAGTTGAAAAAATTGGCTCCTGAAAAAGTGGACT
TGTCTAAAAACAAGGTCCTTCAAAAGGCCAAGAAAAAACGAGCTCCAAAGGTGGGAGATGATATCGTGGTTCTCAGTTAT
GGTCAGCGTGGTACCTTGACCAGTCAACTCAAGGACGGCCGCTGGGAAGCCCAAGTTGGCTTGATTAAGATGACCTTGGA
AGAGAAAGAGTTTGATCTTGTTCAAGCCCAGCAAGAAAAACTAGTCAAGAAGAAACAGGTCAATGTTGTGAAACGAACTT
CTGGGCGAGGACCTCAAGCTAGACTGGATCTTCGAGGCAAGCGCTATGAAGAAGCCATGAATGAGCTAGATACCTTCATC
GACCAAGCCTTGCTTAACAATATGGCTCAAGTTGATATCATCCATGGTATCGGAACAGGAGTCATCCGTGAAGGAGTTAC
CAAATACTTGCAAAGAAACAAACATGTCAAGAGTTTCGGCTATGCCCCACAAAATGCTGGAGGCAGTGGTGCGACTATTG
TCACTTTTAAAGGATAG

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-506)

MutS2 and Smr-associated SH3 domain (MSSS)

(631-670)

Smr domain (Smr)

(702-777)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

40.582

100

0.413