Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   H7680_RS03845 Genome accession   NZ_AP023394
Coordinates   745851..746717 (+) Length   288 a.a.
NCBI ID   WP_003057428.1    Uniprot ID   A0AAE6NAQ1
Organism   Streptococcus dysgalactiae subsp. equisimilis strain 159     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 740851..751717
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7680_RS03820 (SDSE159_07160) atpD 741887..743293 (+) 1407 WP_003057452.1 F0F1 ATP synthase subunit beta -
  H7680_RS03825 (SDSE159_07170) - 743306..743722 (+) 417 WP_003050138.1 F0F1 ATP synthase subunit epsilon -
  H7680_RS03830 (SDSE159_07180) - 744051..744287 (+) 237 WP_274047614.1 DUF1146 family protein -
  H7680_RS03835 (SDSE159_07190) murA 744352..745623 (+) 1272 WP_015016870.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  H7680_RS03840 (SDSE159_07200) - 745627..745815 (+) 189 WP_003057490.1 DNA-directed RNA polymerase subunit beta -
  H7680_RS03845 (SDSE159_07210) endA 745851..746717 (+) 867 WP_003057428.1 DNA/RNA non-specific endonuclease Machinery gene
  H7680_RS03850 (SDSE159_07220) pheS 747000..748043 (+) 1044 WP_003057440.1 phenylalanine--tRNA ligase subunit alpha -
  H7680_RS03855 (SDSE159_07230) pheT 748253..750658 (+) 2406 WP_003057457.1 phenylalanine--tRNA ligase subunit beta -
  H7680_RS03860 (SDSE159_07240) - 750768..751145 (+) 378 WP_003057473.1 OsmC family protein -
  H7680_RS03865 (SDSE159_07250) - 751138..751524 (+) 387 WP_139818739.1 DUF1722 domain-containing protein -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 31917.94 Da        Isoelectric Point: 10.0750

>NTDB_id=83062 H7680_RS03845 WP_003057428.1 745851..746717(+) (endA) [Streptococcus dysgalactiae subsp. equisimilis strain 159]
MLTRKKRKRVLNSFLLILLVLGSSYLAKSDFIASNHPIKQIYRTVLGDKGESSSESKEVYSEVPTEALSASVLTKSIKEQ
LGSDIEWNGAGAYIINRNKTDLNASVASLPYANNETKWVQGQKVPTRANALLTKSTRQYRNRYQTDNAYRTFKPAGWHQL
HHLKGNYDHAVDRGHLLGYALVGGLKGFDASTSNPDNIATQLSWANQADKPYSTGQNYYEGLVRRALDKGKRVRYRVTLL
YDGDNLLASGSQLEAKSADGSLAFNVFVPNVQAGLTVDYRTGQIAINP

Nucleotide


Download         Length: 867 bp        

>NTDB_id=83062 H7680_RS03845 WP_003057428.1 745851..746717(+) (endA) [Streptococcus dysgalactiae subsp. equisimilis strain 159]
ATGTTAACAAGGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAGTTACCTTGC
TAAGAGTGATTTCATAGCTAGCAATCACCCTATTAAGCAAATTTATCGTACCGTTTTGGGAGATAAGGGTGAATCATCAT
CAGAATCAAAAGAAGTCTATAGTGAGGTTCCCACAGAAGCCCTATCCGCTTCTGTCTTGACCAAATCCATTAAGGAACAA
TTAGGTTCCGATATTGAATGGAATGGAGCAGGCGCCTATATTATCAACAGGAACAAAACAGATTTAAACGCAAGCGTAGC
CAGTCTGCCCTATGCCAATAATGAAACCAAATGGGTCCAAGGACAAAAGGTTCCTACTAGAGCTAATGCCTTACTTACTA
AGTCGACACGACAGTATCGAAATCGCTATCAAACGGACAATGCTTATCGTACCTTCAAGCCTGCTGGTTGGCACCAATTA
CATCACTTAAAAGGAAATTATGACCACGCAGTTGATAGAGGACATTTGCTAGGTTATGCTTTAGTCGGTGGACTGAAAGG
TTTTGATGCATCTACCAGTAATCCTGATAACATTGCTACTCAACTAAGTTGGGCCAATCAAGCAGATAAACCCTATTCGA
CAGGTCAAAATTACTATGAAGGCTTAGTACGTCGTGCATTGGATAAGGGCAAAAGGGTCCGTTATCGTGTTACCTTGCTT
TATGATGGTGATAATCTGTTAGCCAGTGGCAGCCAGTTAGAGGCCAAATCTGCCGATGGGAGTTTAGCATTTAACGTGTT
TGTTCCAAATGTTCAAGCAGGGTTGACGGTTGATTATCGAACAGGACAGATTGCCATCAATCCCTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(121-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

62.338

80.208

0.5
  endA Streptococcus pneumoniae D39

62.338

80.208

0.5
  endA Streptococcus pneumoniae R6

62.338

80.208

0.5
  endA Streptococcus pneumoniae TIGR4

62.338

80.208

0.5

Multiple sequence alignment